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A revised nomenclature for the lemur family of protein kinases
The lemur family of protein kinases has gained much interest in recent years as they are involved in a variety of cellular processes including...
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Fungal taxonomy and sequence-based nomenclature
The identification and proper naming of microfungi, in particular plant, animal and human pathogens, remains challenging. Molecular identification is...
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Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A2 receptors
The adenosine subfamily G protein-coupled receptors A 2A R and A 2B R have been identified as promising cancer immunotherapy candidates. One of the A 2A R/A
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Cuticle supplementation and nitrogen recycling by a dual bacterial symbiosis in a family of xylophagous beetles
Many insects engage in stable nutritional symbioses with bacteria that supplement limiting essential nutrients to their host. While several plant...
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Computational discovery of dual potential inhibitors of SARS‐CoV‐2 spike/ACE2 and Mpro: 3D-pharmacophore, docking-based virtual screening, quantum mechanics and molecular dynamics
To find drugs against COVID-19, caused by the SARS-CoV-2, promising targets include the fusion of the viral spike with the human...
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Dual function of a highly conserved bacteriophage tail completion protein essential for bacteriophage infectivity
Infection of bacteria by phages is a complex multi-step process that includes specific recognition of the host cell, creation of a temporary breach...
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Studies on European rust fungi, Pucciniales: molecular phylogeny, taxonomy, and nomenclature of miscellaneous genera and species in Pucciniastraceae and Coleosporiaceae
Using molecular phylogenetic analyses (ITS) and morphological data obtained from light and electron microscopy, some European and North American...
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Ryanodine receptor 1-related disorders: an historical perspective and proposal for a unified nomenclature
The RYR1 gene, which encodes the sarcoplasmic reticulum calcium release channel or type 1 ryanodine receptor (RyR1) of skeletal muscle, was sequenced...
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Morphological Diversity of Icosahedral Viruses
Abstract —The article is devoted to a morphological diversity of icosahedral viruses (individual capsids and the structure of the diversity in...
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Current Fungal Taxonomy and Developments in the Identification System
A functional identification system is the core and basis of fungal taxonomy, which provides sufficient diagnostic characteristics for species...
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Advances in management of metabolic dysfunction-associated steatotic liver disease: from mechanisms to therapeutics
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of chronic liver disease that affects over 30% of the world’s...
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Molecularly tagged genes and quantitative trait loci in cucumber with recommendations for QTL nomenclature
Cucumber, Cucumis sativus L. (2 n = 2 x = 14), is an important vegetable crop worldwide. It was the first specialty crop with a publicly available...
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Whole mitochondrial genome sequencing provides new insights into the phylogeography of loggerhead turtles (Caretta caretta) in the Mediterranean Sea
Population structure and phylogeography of the loggerhead sea turtle ( Caretta caretta ) have so far been assessed mainly by mitochondrial DNA (mtDNA)...
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A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases
Cross-kingdom herbal miRNA was first reported in 2012. Using a modified herbal extraction protocol, we obtained 73,677,287 sequences by RNA-seq from...
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Structural Insights into the Mechanism of DUOX1-DUOXA1 Complex
Dual oxidases (DUOX), dedicated enzymes for regulated hydrogen peroxide production, play essential roles in many biological processes. Recent advance... -
Forecasting the number of species of asexually reproducing fungi (Ascomycota and Basidiomycota)
Asexually reproducing fungi play a significant role in essential processes in managed and wild ecosystems such as nutrients cycling and multitrophic...
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Mitogen-Activated Protein Kinase: A Potent Signaling Protein that Combats Biotic and Abiotic Stress in Plants
Serine kinases, also identified as mitogen-activated protein kinases (MAPKs), are involved in the transmission of cellular signals that carry out...
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Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term ‘lncRNAs’ encompasses RNA...
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A beginner’s guide on the use of brain organoids for neuroscientists: a systematic review
BackgroundThe first human brain organoid protocol was presented in the beginning of the previous decade, and since then, the field witnessed the...
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From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy
Severe cardiac remodeling leading to heart failure in individuals harboring pathogenic LMNA variants, known as cardiolaminopathy, poses a significant...