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Skeletal and cardiac muscle have different protein turnover responses in a model of right heart failure
Right heart failure (RHF) is a common and deadly disease in aged populations. Extra-cardiac outcomes of RHF such as skeletal muscle atrophy...
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Possibilities of Studying Force and Energy Characteristics of the Cardiac Muscle in Microgravity Using Ballistocardiography
AbstractThe article is devoted to the assessment of force and energy characteristics of the heart muscle in microgravity using the method of spatial...
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Granulocyte-colony stimulating factor ameliorates di-ethylhexyl phthalate-induced cardiac muscle injury via stem cells recruitment, Desmin protein regulation, antifibrotic and antiapoptotic mechanisms
Phthalates are common plasticizers present in medical-grade plastics and other everyday products. Di-ethylhexyl phthalate (DEHP) has been noted as a...
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Cryo-electron tomography of intact cardiac muscle reveals myosin binding protein-C linking myosin and actin filaments
Myosin binding protein C (MyBP-C) is an accessory protein of the thick filament in vertebrate cardiac muscle arranged over 9 stripes of intervals of...
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Keratose Hydrogel Drives Differentiation of Cardiac Vascular Smooth Muscle Progenitor Cells: Implications in Ischemic Treatment
Peripheral artery disease (PAD) is a common vascular disorder in the extremity of limbs with limited clinical treatments. Stem cells hold great...
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Cardiac Progenitor Cells in Cardiac Tissue Repair
Since the discovery of Cardiac progenitor cells (CPCs) in the early 1990s, they have been studied extensively in different models and clinical trials...
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Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders
The contribution of the epicardium, the outermost layer of the heart, to cardiac regeneration has remained controversial due to a lack of suitable...
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Cardiac troponin T and autoimmunity in skeletal muscle aging
Age-related muscle mass and strength decline (sarcopenia) impairs the performance of daily living activities and can lead to mobility...
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Basic Structure of Skeletal Muscle
Building on the foundational understanding established in the first chapter, Chap. 2 explores the burgeoning...
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Skeletal Muscle Energy Metabolism & Contraction
Skeletal muscle contraction and energy metabolism are closely intertwined processes essential for maintaining physiological functions and supporting...
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Aging and short-term calorie restriction differently affect the cardiac and skeletal muscle expression of genes regulating energy substrate utilization in male rats
Aging affects the energy metabolism differently in the cardiac and skeletal muscles. The study aim was to assess the effects of short-term calorie...
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Mechanobiology of Cardiac Fibroblasts in Cardiac Remodeling
Although cardiomyocytes (CMs) function as the electrical and contractile units of the myocardium, the maintenance and turnover of the cardiac...
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The effect of gender and obesity in modulating cross-bridge function in cardiac muscle fibers
The effect of obesity on cross-bridge (CB) function was investigated in mice lacking functional Melanocortin-4 Receptor (MC4R −/− ), the loss of which...
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The role of cardiac microenvironment in cardiovascular diseases: implications for therapy
Due to aging populations and changes in lifestyle, cardiovascular diseases including cardiomyopathy, hypertension, and atherosclerosis, are the...
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Cationic amino acid transporters and their modulation by nitric oxide in cardiac muscle cells
Cationic amino acid transporters (CATs) play a central role in the supply of the substrate L-arginine to intracellular nitric oxide synthases (NOS),...
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Immunofluorescence Labeling of Skeletal Muscle in Development, Regeneration, and Disease
Skeletal muscle is composed of long multinucleated cells, termed myofibers, that are formed through the activation and differentiation of resident...
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Cardiac Microvascular Endothelial Cells and Pressure Overload-Induced Cardiac Fibrosis
Heart failure is one of the main causes of death worldwide. It is a consequence of ultimately maladaptive cardiac remodelling processes, i.e.,...
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The Effects of Exercise on Skeletal Muscle
This chapter investigates the profound effects of exercise on skeletal muscle. In its many forms, exercise plays an indisputable role in influencing...
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Stem Cells and Therapies in Cardiac Regeneration
Ischemic heart diseases (IHD) are a significant cause of death all over the world increasing the cardiovascular disease (CVD) burden. Blockade of...
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Stimulatory Effect of Low Concentrations of Eu3+ on Spontaneous Cardiac Contractions
AbstractNegative cumulative effects of lanthanides on the human body are well known; they are mainly related to the toxic effects of rare earth...
