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Intravenous Bacille Calmette–Guérin vaccination protects simian immunodeficiency virus-infected macaques from tuberculosis
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the most common cause of death in people living with human immunodeficiency virus (HIV)....
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Virus as Teratogenic Agents
Viral infectious diseases are important causes of reproductive disorders, as abortion, fetal mummification, embryonic mortality, stillbirth, and...
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Role of sialylated glycans on bovine lactoferrin against influenza virus
Influenza is a worldwide plague caused by the influenza virus (IAV) infection, which is initiated by specific recognition with sialic acids on host...
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Antibodies from dengue patients with prior exposure to Japanese encephalitis virus are broadly neutralizing against Zika virus
Exposure to multiple mosquito-borne flaviviruses within a lifetime is not uncommon; however, how sequential exposures to different flaviviruses shape...
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Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and In Silico insights
BackgroundThe emergence of different viral infections calls for the development of new, effective, and safe antiviral drugs. Glycyrrhiza glabra is a...
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Mpox virus infection and drug treatment modelled in human skin organoids
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models that recapitulate skin infection by MPXV are lacking. Here...
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Analysis of Antimicrobial Activity of Monocytic Myeloid-Derived Suppressor Cells in Infection with Mycobacterium tuberculosis and Human Immunodeficiency Virus
Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. Since...
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Differential gene expression and immune cell infiltration in maedi-visna virus-infected lung tissues
BackgroundMaedi-visna virus (MVV) is a lentivirus that infects monocyte/macrophage lineage cells in sheep, goats, and wild ruminants and causes...
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Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo
Chikungunya virus (CHIKV) has recently emerged to cause millions of human infections worldwide. Infection can induce the formation of long...
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Disruption of type I interferon pathway and reduced production of IFN-α by parabens in virus-infected dendritic cells
BackgroundParabens are widely used preservatives commonly found in foods, cosmetics, and industrial products. Several studies have examined the...
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A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection
BackgroundVaricella zoster virus (VZV), which is a human restricted alpha-herpesvirus, causes varicella (chickenpox) and zoster (shingles). The...
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Bluetongue Virus Detection Using Microspheres Conjugated with Monoclonal Antibodies against Group-Specific Protein Vp7 by Flow Virometry
Abstract—Bluetongue is a reemerging transmissive infectious disease that threatens all countries with intensive livestock production. In cattle,...
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Repurposing of approved antivirals against dengue virus serotypes: an in silico and in vitro mechanistic study
Dengue is an emerging, mosquito-borne viral disease of international public health concern. Dengue is endemic in more than 100 countries across the...
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Varicella-Zoster Virus ORF39 Transmembrane Protein Suppresses Interferon-Beta Promoter Activation by Interacting with STING
Varicella-Zoster virus (VZV) causes varicella in primary infection of children and zoster during reactivation in adults. Type I interferon (IFN)...
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Rapid, visual, label-based biosensor platform for identification of hepatitis C virus in clinical applications
ObjectivesIn the current study, for the first time, we reported a novel HCV molecular diagnostic approach termed reverse transcription loop-mediated...
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TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation
BackgroundRecognition of viral invasion by innate antiviral immune system triggers activation of the type I interferon (IFN-I) and proinflammatory...
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Clinical research review: usefulness of bovine lactoferrin in child health
Lactoferrin (LF) is abundant in human milk and plays an important role in the health of children. Bovine LF (bLF) has high homology with human LF and...
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Functional and structural basis of human parainfluenza virus type 3 neutralization with human monoclonal antibodies
Human parainfluenza virus type 3 (hPIV3) is a respiratory pathogen that can cause severe disease in older people and infants. Currently, vaccines...
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A chemiluminescent magnetic microparticle immunoassay for the detection of antibody against African swine fever virus
AbstractThe p30 protein is abundantly expressed in the early stage of African swine fever virus (ASFV) infection. Thus, it is an ideal antigen...
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Andrographolide exerts anti-respiratory syncytial virus activity by up-regulating heme oxygenase-1 independent of interferon responses in human airway epithelial cells
BackgroundRespiratory syncytial virus (RSV) is the leading cause of mortality and morbidity in children under the age of five. Despite this, there is...
