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Antioxidant, Antimicrobial, and Antiproliferative Activities of Some Edible Wild Mushrooms
AbstractEdible mushrooms are dietary products that are widely consumed in many societies. It is known that mushrooms, which stand out with their...
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Synthesis of bis-thiohydantoin derivatives as an antiproliferative agents targeting EGFR inhibitory pathway
( R )/( S )-the two enantiomers of...
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Enhanced antiproliferative activity of phycoerythrin through microencapsulation
Phycoerythrin, a phycobiliprotein recognized for its brilliant crimson hue and essential role in light harvesting during photosynthesis, was...
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The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells
(1R,2R-diaminocyclohexane)(dihydropyrophosphato) platinum(II), also abbreviated as RRD2, belongs to a class of potent antitumor platinum cytostatics...
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Mechanisms of Antiproliferative Effect of Streptococcal Arginine Deiminase on Jurkat Lymphoblastic Leukemia Cells
AbstractArginine deprivation strategy is considered as a promising trend in cancer therapy. The aim of the study was to investigate the influence of...
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Antiproliferative, anti-inflammatory, and antioxidant activity of aqueous extracts from Origanum compactum benth aerial part
Origanum compactum Benth (Lamiaceae), is an endemic plant of northern Morocco. rich in phenolic compounds that is commonly used in traditional...
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New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization
New 3-substituted oxindole derivatives were designed and synthesized as antiproliferative agents. The antiproliferative activity of compounds 6a–j ...
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Green synthesis, characterization of melatonin-like drug bioconjugated CoS quantum dots and its antiproliferative effect on different cancer cells
BackgroundQuantum dots are usually particles smaller than 100 nm and have a low toxic effect. This study aimed to bioconjugate the anticancer...
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Synthesis and In vitro Antiproliferative Activity of 5-Halogen-6-nitrobenzo[c][1,2,5]selenadiazoles on A549 Cells
AbstractSelenadiazoles are of a broad spectrum of promising anticancer agents. However, excessive synthetic steps, larger molecular size and erratic...
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In Vitro Antiproliferative Effect of Angiopteris evecta (G. Forst.) Hoffm. Extracts against Cultured HT-29 Colon Cancer Cells
Angiopteris evecta (G. Forst.) Hoffm. belongs to the family Angiopteridaceae. It is commonly called giant or king fern. The plant is used as a...
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An efficient one-pot synthesis and docking studies of bioactive new antiproliferative dispiro[oxindole/acenaphthylenone‒benzofuranone] pyrrolidine scaffolds
A new and efficient method has been developed to synthesize dispiro[oxindole/acenaphthylenone-benzofuranone]pyrrolidine compounds. This is done by...
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Chemical Composition and In Vitro Antimicrobial, Antioxidant, and Antiproliferative Studies of the Lamium galeobdolon L. (L.) Essential Oil
AbstractThe current study aimed to evaluate the chemical composition and bioactive properties of Lamium galeobdolon (L.) L. After obtaining an...
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Cryptochrome 2 acetylation attenuates its antiproliferative effect in breast cancer
Breast cancer is the most commonly diagnosed cancer, and its global impact is increasing. Its onset and progression are influenced by multiple cues,...
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Chemotherapeutic and Antiproliferative Effect of Purified Protein from Marine Catfish Tachysurus Dussumieri on Human Colon Cancer Cell Line
The present study aimed to investigate the purified protein from the epidermal mucus of marine catfish Tachysurus dussumieri on the human colon...
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In Vitro Cytotoxic Activity and In Vivo Antiproliferative Activity of Ethyl Acetate Fraction of Bunium bulbocastanum Seed Against Prostatic Neoplasia
Several in vitro investigations of the therapeutic characteristics of B. bulbocastanum have shown that it has cytotoxic, antifungal, and...
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Design, Synthesis, Molecular Docking Anticancer, Antiproliferative and Antioxidant Studies of Novel Chalcones Derivatives
AbstractA series of chalcones were synthesized and characterized by different spectroscopic techniques. The antioxidant properties of the compounds...
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Antimicrobial, antiproliferative activities and molecular docking of metabolites from Alternaria alternata
Endophytic fungi allied to plants have sparked substantial promise in discovering new bioactive compounds. In this study, propagation of the...
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Citrus Essential Oils: A Rational View on its Chemical Profiles, Mode of Action of Anticancer Effects/Antiproliferative Activity on Various Human Cancer Cell Lines
Cancer is a complex genetic disorder due to uncontrolled growth of abnormal cells in the body, causes damage to the immune system, and may lead to...
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Synthesis, antiproliferative activity, and molecular modeling of novel 4-methylcoumarin derivatives and/or nitric oxide donor hybrids
AbstractTwo new 4-methylcoumarin derivatives ( 3a–f and 4a–f ) were designed, synthesized, and evaluated for their cytotoxic activity. Different...
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UPLC–ESI–QTOF–MS profiling, antioxidant, antidiabetic, antibacterial, anti-inflammatory, antiproliferative activities and in silico molecular docking analysis of Barleria strigosa
BackgroundThis study investigated the in vitro antidiabetic, antioxidant, antibacterial, anti-inflammatory and antiproliferative effects of B....
