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Antibiotic-free production of sucrose isomerase in Bacillus subtilis by genome integration
Sucrose isomerase (SIase) catalyzes the hydrolysis and isomerization of sucrose to form isomaltulose, a valuable functional sugar widely used in the...
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Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice
Probiotic supplements are suggested to promote human health by preventing pathogen colonization. However, the mechanistic bases for their efficacy in...
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An overview of the two-component system GarR/GarS role on antibiotic production in Streptomyces coelicolor
AbstractThe Streptomyces genus comprises Gram-positive bacteria known to produce over two-thirds of the antibiotics used in medical practice. The...
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FtsZ phosphorylation pleiotropically affects Z-ladder formation, antibiotic production, and morphogenesis in Streptomyces coelicolor
The GTPase FtsZ forms the cell division scaffold in bacteria, which mediates the recruitment of the other components of the divisome. Streptomycetes...
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Examining antibiotic use in Kenya: farmers’ knowledge and practices in addressing antibiotic resistance
BackgroundAntibiotics hold the promise of mitigating the spread of livestock diseases while enhancing productivity. However, there is global concerns...
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A biostatistical approach for augmenting rare bianthraquinone antibiotic production by Streptomyces sp. RA-WS2 using Taguchi design
Consistent production of bioactives from microbial sources remains a big challenge for fermentation based bio-processes. Setomimycin, a rare...
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Efficient green silver nanoparticles-antibiotic combinations against antibiotic-resistant bacteria
Antibiotic-resistant bacterial strains and the consequent surge in infections caused by them have become major public health concerns. Silver...
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Biosensors for Inducers of Transient Antibiotic Resistance
The acquisition of an antibiotic resistance phenotype can be due to genetic modifications (heritable) or transient changes in bacterial physiology...
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A review of current antibiotic resistance and promising antibiotics with novel modes of action to combat antibiotic resistance
The emergence and transmission of antibiotic resistance is a global public health crisis with significant burden on healthcare systems, resulting in...
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Protistan predation selects for antibiotic resistance in soil bacterial communities
Understanding how antibiotic resistance emerges and evolves in natural habitats is critical for predicting and mitigating antibiotic resistance in...
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Impact of environment on transmission of antibiotic-resistant superbugs in humans and strategies to lower dissemination of antibiotic resistance
Antibiotics are the most efficient type of therapy developed in the twentieth century. From the early 1960s to the present, the rate of discovery of...
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Antibiotic Residues and Zinc Concentrations in the Livers and Kidneys of Portuguese Piglets—Relationship to Antibiotic and Zinc Resistance in Intestinal Escherichia coli
Metal ions such as zinc and copper have been used as alternatives to antibiotics, to improve animal health and growth rates in pig farming. This...
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Biosecurity and Disinfectant Resistance in a Post-antibiotic Era
Antibiotic resistance may lead humanity into a post-antibiotic era. The prevalence of multidrug-resistant microorganisms has prompted research into...
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Livestock Production
Livestock is a key component of sustainable agriculture and contributes to food security, nutrition, poverty reduction, and economic growth....
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The Pseudomonas aeruginosa Resistome: Permanent and Transient Antibiotic Resistance, an Overview
One of the most concerning characteristics of Pseudomonas aeruginosa is its low susceptibility to several antibiotics of common use in clinics, as...
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Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous infectious and autoimmune diseases of the gastrointestinal tract....
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Novel insights into the co-selection of metal-driven antibiotic resistance in bacteria: a study of arsenic and antibiotic co-exposure
The simultaneous development of antibiotic resistance in bacteria due to metal exposure poses a significant threat to the environment and human...
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Co-selection for antibiotic resistance by environmental contaminants
The environment is increasingly recognised as a hotspot for the selection and dissemination of antibiotic resistant bacteria and antibiotic...
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Antibiotic-Induced Biofilm Formations in Pseudomonas aeruginosa Strains KPW.1-S1 and HRW.1-S3 are Associated with Increased Production of eDNA and Exoproteins, Increased ROS Generation, and Increased Cell Surface Hydrophobicity
Pseudomonas aeruginosa is a medically important opportunistic pathogen due to its intrinsic ability to form biofilms on different surfaces as one of...
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PGPR in Biofilm Formation and Antibiotic Production
The dynamic habitat existing around the plant root, the rhizosphere, is mainly inhabited by the bacteria and is collectively termed as plant...