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Universal Spectrum Identifier for mass spectra
Mass spectra provide the ultimate evidence to support the findings of mass spectrometry proteomics studies in publications, and it is therefore...
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WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing Klebsiella pneumoniae strain: a novel molecular target of selective flavonoids
The research aimed to establish a multidrug-resistant Klebsiella pneumoniae -induced genetic model for mastitis considering the alternative mechanisms...
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PhyloSophos: a high-throughput scientific name map** algorithm augmented with explicit consideration of taxonomic science, and its application on natural product (NP) occurrence database processing
BackgroundThe standardization of biological data using unique identifiers is vital for seamless data integration, comprehensive interpretation, and...
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Social spatial cognition: social distance dynamics as an identifier of social interactions
We suggest that socio-spatial behavior, which is an interaction between social and spatial cognition, can be viewed as a set of excursions that...
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Changes in Histone Code Regulation during the Initiation of Paraptosis-Like Death of HEp-2 Tumor Cells by Oxidized Disulfiram Derivatives
Abstract —Disulfiram (DSF) and its oxidized derivatives (DSFoxy) are currently being investigated as potential anticancer agents. We previously found...
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Reconciling Inconsistent Molecular Structures from Biochemical Databases
Information on the structure of molecules, retrieved via biochemical databases, plays a pivotal role in various disciplines, such as metabolomics,...
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Proteomic profile of tepary bean seed storage proteins in germination with low water potential
BackgroundTepary bean ( Phaseolus acutifolius A. Gray) is one of the five species domesticated from the genus Phaseolus with genetic resistance to...
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Tidyproteomics: an open-source R package and data object for quantitative proteomics post analysis and visualization
BackgroundThe analysis of mass spectrometry-based quantitative proteomics data can be challenging given the variety of established analysis...
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Proteomic analysis of common bean (Phaseolus vulgaris L.) leaves showed a more stable metabolism in a variety responsive to biological nitrogen fixation
The common bean ( Phaseolus vulgaris L.) can supply part of its N demand through biological nitrogen fixation (BNF) in symbiosis with rhizobia....
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EZCancerTarget: an open-access drug repurposing and data-collection tool to enhance target validation and optimize international research efforts against highly progressive cancers
The expanding body of potential therapeutic targets requires easily accessible, structured, and transparent real-time interpretation of molecular...
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Identification and characterization of abiotic stress-tolerant genes in rice (Oryza sativa L.): a computational approach
Rice serves as the main food source in many regions of the world. However, rice production is impacted by abiotic stress including drought, salt,...
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Network pharmacology combined with molecular docking and dynamics to assess the synergism of esculetin and phloretin against acute kidney injury-diabetes comorbidity
Acute kidney injury (AKI) is a global health concern with high incidence and mortality, where diabetes further worsens the condition. The available...
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Comparative proteomic investigation unravels the pathobiology of Mycobacterium fortuitum biofilm
AbstractBiofilm formation by Mycobacterium fortuitum causes serious threats to human health due to its increased contribution to nosocomial...
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SALON ontology for the formal description of sequence alignments
BackgroundInformation provided by high-throughput sequencing platforms allows the collection of content-rich data about biological sequences and...
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Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0
Genome-scale metabolic models (GEMs) are computational representations that enable mathematical exploration of metabolic behaviors within cellular...
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iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
BackgroundPatientswith immunodeficiency virus-1 (HIV-1) infection are challenging to be cured completely due to the existence of HIV-1 latency...
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Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics
BackgroundDCM is a common cardiomyopathy worldwide, which is characterized by ventricular dilatation and systolic dysfunction. DCM is one of the most...
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Comparative proteomic analysis of the ovarian fluid and eggs of Siberian sturgeon
BackgroundSturgeon species are living fossils that exhibit unique reproductive characteristics, and elucidation of the molecular processes governing...
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Pan-genome de Bruijn graph using the bidirectional FM-index
BackgroundPan-genome graphs are gaining importance in the field of bioinformatics as data structures to represent and jointly analyze multiple...
