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Microarray-Based Detection and Identification of Bacterial and Viral Plant Pathogens
The development and application of diagnostic procedures are influenced by a variety of circumstances. Plant viruses, unlike cellular diseases, have...
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A Hybrid Protocol for Finding Novel Gene Targets for Various Diseases Using Microarray Expression Data Analysis and Text Mining
The advancement in technology for various scientific experiments and the amount of raw data produced from that is enormous, thus giving rise to...
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Microarray analysis of long non-coding RNA expression profiles in low high-density lipoprotein cholesterol disease
BackgroundLow high-density lipoprotein cholesterol (HDL-C) disease with unknown etiology has a high prevalence in the **njiang Kazak population. In...
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Relevance of Bioinformatics and Database in Omics Study
Bioinformatics is an interdisciplinary branch of biological sciences that assists biologists to interpret and extract the biological information from...
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Differential gene expression analysis of the resprouting process in Pinus canariensis provides new insights into a rare trait in conifers
Resprouting is crucial in population dynamics in response to wildfires or herbivory. This trait, common in angiosperms, is considered rare in...
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Identification and validation of key biomarkers and potential therapeutic targets for primary open-angle glaucoma
Primary open-angle glaucoma (POAG) is a prevalent cause of blindness worldwide, resulting in degeneration of retinal ganglion cells and permanent...
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Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy
Characterization of the diverse malignant and stromal cell states that make up soft tissue sarcomas and their correlation with patient outcomes has...
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Roles of Skeletal Muscle in Development: A Bioinformatics and Systems Biology Overview
The ability to assess various cellular events consequent to perturbations, such as genetic mutations, disease states and therapies, has been recently...
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Expression of human RECQL5 in Saccharomyces cerevisiae causes transcription defects and transcription-associated genome instability
RECQL5 is a member of the conserved RecQ family of DNA helicases involved in the maintenance of genome stability that is specifically found in higher...
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Bioinformatics and Computational Tools
Proteomics and bioinformatics are now considered as very important tools for the characterization and understanding of any food biomolecules. It has...
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Diagnosis and Detection of Soil-Borne Fungal Phytopathogens in Major Crops
Phytopathogenic soil-borne fungal species can inflict huge economic disturbances in the global agricultural sector. Soil-borne diseases, incited by...
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Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in human aortic dissection
BackgroundMany studies on long chain non-coding RNAs (lncRNAs) are published in recent years. But the roles of lncRNAs in aortic dissection (AD) are...
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Systems Biology: necessary developments and trends
At the end of this definition of Systems Biology through exampling, we discuss ambitions, goals, and challenges relating to this new discipline. We...
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Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics
Postnatal cell fate is postulated to be primarily determined by the local tissue microenvironment. Here, we find that Mediator 1 ( Med1 ) dependent...
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Diagnosis of Genetic Disorders by DNA Analysis
DNA diagnostic tools have revolutionized modern medicine. Rapid and cost-effective technologies have changed the way genetic diseases are being...
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Omics to Understand Drought Tolerance in Plants: An Update
Drought is a major threat to many plants and especially with rice. Rice is a staple food for more than 3.5 billion people worldwide. There is a need...
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Which data subset should be augmented for deep learning? a simulation study using urothelial cell carcinoma histopathology images
BackgroundApplying deep learning to digital histopathology is hindered by the scarcity of manually annotated datasets. While data augmentation can...
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NMR-based comparative metabolomics of quiescent muscle cells
Adult muscle tissue largely comprised of differentiated myofibers also harbors quiescent muscle-resident stem cells (MuSCs) that are responsible for...
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Cell-in-cell structure mediates in-cell killing suppressed by CD44
Penetration of immune cells into tumor cells was believed to be immune-suppressive via cell-in-cell (CIC) mediated death of the internalized immune...
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The genome of the filamentous fungus Ashbya gossypii: annotation and evolutionary implications
The 9.2 Mb genome of the filamentous fungus Ashbya gossypii consists of seven chromosomes carrying 4718 protein coding genes, 194 tRNA genes, at...