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Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1
Limited understanding exists regarding how aging impacts the cellular and molecular aspects of the human ovary. This study combines single-cell RNA...
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Differences in spatiotemporal brain network dynamics of Montessori and traditionally schooled students
Across development, experience has a strong impact on the way we think and adapt. School experience affects academic and social-emotional outcomes,...
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Simultaneous spatiotemporal transcriptomics and microscopy of Bacillus subtilis swarm development reveal cooperation across generations
Development of microbial communities is a complex multiscale phenomenon with wide-ranging biomedical and ecological implications. How biological and...
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DBlink: dynamic localization microscopy in super spatiotemporal resolution via deep learning
Single-molecule localization microscopy (SMLM) has revolutionized biological imaging, improving the spatial resolution of traditional microscopes by...
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Contrasting responses of spatiotemporal patterns of cropland to climate change in Northeast China
Understanding the relationship between climate change and cropland spatiotemporal patterns is critical for develo** government policy and assisting...
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Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets
Efficient gene expression requires RNA polymerase II (RNAPII) to find chromatin targets precisely in space and time. How RNAPII manages this complex...
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Distinct spatiotemporal patterns of cortical thinning in Alzheimer’s disease-type cognitive impairment and subcortical vascular cognitive impairment
Previous studies on Alzheimer’s disease-type cognitive impairment (ADCI) and subcortical vascular cognitive impairment (SVCI) has rarely explored...
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Spatiotemporal control of RNA metabolism and CRISPR–Cas functions using engineered photoswitchable RNA-binding proteins
RNA molecules perform various crucial roles in diverse cellular processes, from translating genetic information to decoding the genome, regulating...
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A spatiotemporal proteomic map of human adipogenesis
White adipocytes function as major energy reservoirs in humans by storing substantial amounts of triglycerides, and their dysfunction is associated...
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Small GTPases and Spatiotemporal Regulation of Pollen Tube Growth
During in vivo growth, pollen tubes make a long journey toward the ovule, responding to long- and short-distance guidance cues and elongating...
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Decoding the spatiotemporal regulation of transcription factors during human spinal cord development
The spinal cord is a crucial component of the central nervous system that facilitates sensory processing and motor performance. Despite its...
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Radiopharmaceutical transport in solid tumors via a 3-dimensional image-based spatiotemporal model
Lutetium-177 prostate-specific membrane antigen ( 177 Lu-PSMA)-targeted radiopharmaceutical therapy is a clinically approved treatment for patients...
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Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition
Autopsy studies indicated that the locus coeruleus (LC) accumulates hyperphosphorylated tau before allocortical regions in Alzheimer’s disease. By...
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Spatiotemporal distribution of invertebrate fauna in a mesovoid shallow substratum in iron formations
Iron Formations (IF) are among the most threatened environments due to the extensive mining activities. Mesovoid Shallow Substratum (MSS) in IF...
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A zero-inflated model for spatiotemporal count data with extra zeros: application to 1950–2015 tornado data in Kansas
In many tornado climate studies, the number of tornado touchdowns is often the primary outcome of interest. These outcome measures are usually...
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Evolutionary radiation strategy revealed in the Scarabaeidae with evidence of continuous spatiotemporal morphology and phylogenesis
Evolutionary biology faces the important challenge of determining how to interpret the relationship between selection pressures and evolutionary...
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Spatiotemporal evolution of urbanization and its implications to urban planning of the megacity, Shanghai, China
ContextUrbanization has profoundly changed urban landscape patterns and morphologies. Understanding the spatiotemporal evolution of these changes and...
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Spatiotemporal distribution of PTEN before directed cell migration in monolayers
The intracellular distribution of phosphatase and tensin homolog (PTEN) is closely related to directed cell migration. In single cells, PTEN...
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Changes in spatiotemporal drought characteristics from 1961 to 2017 in northeastern maize-growing regions, China
A drought is a disaster that poses great threats to maize production. Thus, it is vital to study the spatiotemporal evolution of the standardized...
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Effects of Cascade Reservoirs on Spatiotemporal Dynamics of the Sedimentary Bacterial Community: Co-occurrence Patterns, Assembly Mechanisms, and Potential Functions
AbstractDam construction as an important anthropogenic activity significantly influences ecological processes in altered freshwater bodies. However,...
