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Potential and limitation of biocontrol methods against vibriosis: a review
The shrimp industry has an urgent challenge of managing the outbreak of diseases majorly caused by bacteria and viruses. Vibriosis is one of the most...
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Recent advances in RNA structurome
RNA structures are essential to support RNA functions and regulation in various biological processes. Recently, a range of novel technologies have...
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Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome
BackgroundRoberts syndrome (RBS) is a human developmental disorder caused by mutations in the cohesin acetyltransferase ESCO2. We previously reported...
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The emerging roles for the chromatin structure regulators CTCF and cohesin in neurodevelopment and behavior
Recent genetic and technological advances have determined a role for chromatin structure in neurodevelopment. In particular, compounding evidence has...
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Zebrafish as a Model to Study Cohesin and Cohesinopathies
The cohesin protein complex regulates multiple cellular events including sister chromatid cohesion and gene expression. Several distinct human...
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Horizontal Gene Transfer in Bacteria, an Overview of the Mechanisms Involved
Bacterial transformation, transduction, and “conjugation” can be considered the first horizontal transfer mechanisms in living organisms; these...
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Condensin, master organizer of the genome
A fundamental requirement in nature is for a cell to correctly package and divide its replicated genome. Condensin is a mechanical multisubunit...
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Chromosome structure deficiencies in MCPH1 syndrome
Mutations in the MCPH1 gene result in primary microcephaly in combination with a unique cellular phenotype of defective chromosome condensation....
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Effects of delayed motherhood on hippocampal gene expression in offspring rats
While many studies have examined the pregnancy and health-related outcomes of delayed motherhood for women, less is known concerning the potential...
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Overexpression of a truncated CTF7 construct leads to pleiotropic defects in reproduction and vegetative growth in Arabidopsis
BackgroundEco1/Ctf7 is essential for the establishment of sister chromatid cohesion during S phase of the cell cycle. Inactivation of Ctf7/Eco1 leads...
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Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome
In 2010, a new recessive cohesinopathy disorder, designated Warsaw breakage syndrome (WABS), was described. The individual with WABS displayed...
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Analyzing Sister Chromatid Cohesion in Mammalian Cells
The metaphase chromosome spread technique and subsequent analysis of sister chromatid cohesion is used for (clinical) diagnosis of genetic...
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The Mouse Genome
In Chap. 4 we explained how mouse geneticists were able to develop high-density and high-resolution genetic maps...
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