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Spatially activated conserved auxin-transcription factor regulatory module controls de novo root organogenesis in rice
Main conclusionThis study reveals that the process of crown root development and auxin-induced de novo root organogenesis during in vitro plantlet...
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Jasmonic acid improves barley photosynthetic efficiency through a possible regulatory module, MYC2-RcaA, under combined drought and salinity stress
The combined stress of drought and salinity is prevalent in various regions of the world, affects several physiological and biochemical processes in...
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A self-regulatory cell-wall-sensing module at cell edges controls plant growth
Morphogenesis of multicellular organs requires coordination of cellular growth. In plants, cell growth is determined by turgor pressure and the...
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A regulatory GhBPE-GhPRGL module maintains ray petal length in Gerbera hybrida
The molecular mechanism regulating petal length in flowers is not well understood. Here we used transient transformation assays to confirm that GhPRGL ...
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Regulatory mechanism of the miR172e–LbrAP2 module during the vegetative growth phase transition in Lilium
Main conclusionIt was proved for the first time that the miR172e– LbrAP2 module regulated the vegetative growth phase transition in Lilium , which...
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Unraveling the evolutionary origin of the complex Nuclear Receptor Element (cNRE), a cis-regulatory module required for preferential expression in the atrial chamber
Cardiac function requires appropriate proteins in each chamber. Atria requires slow myosin to act as reservoirs, while ventricles demand fast myosin...
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The ABA–AtNAP–SAG113 PP2C module regulates leaf senescence by dephoshorylating SAG114 SnRK3.25 in Arabidopsis
We previously reported that ABA inhibits stomatal closure through AtNAP-SAG113 PP2C regulatory module during leaf senescence. The mechanism by which...
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A methane–cGMP module positively influences adventitious rooting
Key messageEndogenous cGMP operates downstream of CH 4 control of adventitious rooting, following by the regulation in the expression of cell cycle...
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Identification of a Regulatory Module (PsMYB12L/PsDFR) with Potential Involved in Double-Color Formation in Paeonia suffruticosa “Shima Nishiki”
AbstractPaeonia suffruticosa “Shima Nishiki” is a extremely precious double-color cultivar in the world because of its unique and attractive flower...
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Two florigens and a florigen-like protein form a triple regulatory module at the shoot apical meristem to promote reproductive transitions in rice
Many plant species monitor and respond to changes in day length (photoperiod) for aligning reproduction with a favourable season. Day length is...
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A multi-omics integrative analysis based on CRISPR screens re-defines the pluripotency regulatory network in ESCs
A comprehensive and precise definition of the pluripotency gene regulatory network (PGRN) is crucial for clarifying the regulatory mechanisms in...
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Regulatory Networks
This chapter elaborates on the overview presented in Chapter 3. Gene regulatory networks are complex systems that control the expression of genes in...
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The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
PIWI-clade proteins harness piRNAs of 24–33 nt in length. Of great puzzles are how PIWI-clade proteins incorporate piRNAs of different sizes and...
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Structure and assembly of the NOT10:11 module of the CCR4-NOT complex
NOT1, NOT10, and NOT11 form a conserved module in the CCR4-NOT complex, critical for post-transcriptional regulation in eukaryotes, but how this...
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Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer
SRC is the first identified oncogene, and its aberrant activation has been implicated as a driving event in tumor initiation and progression....
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A LlMYB305-LlC3H18-LlWRKY33 module regulates thermotolerance in lily
The CCCH proteins play important roles in plant growth and development, hormone response, pathogen defense and abiotic stress tolerance. However, the...
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UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4
UBR4 is a 574 kDa E3 ligase (E3) of the N-degron pathway with roles in neurodevelopment, age-associated muscular atrophy and cancer. The catalytic...
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Canadian Regulatory Framework and Regulatory Requirements for Cell and Gene Therapy Products
Health Canada regulates gene therapy products and many cell therapy products as biological drugs under the Canadian Food and Drugs Act and its...