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Mass Spectrometry Approaches for Detection and Determination of Prostaglandins from Biological Samples
Accurate determination of prostaglandins (PGs) from biological samples is critical for understanding their biological functions and interactions...
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Simulation of the Level of Prostaglandins in Open Systems under the Action of Nonsteroidal Anti-Inflammatory Drugs
AbstractModeling the flow and level of prostaglandins in open systems under the action of prostaglandin H synthase (PGHS) inhibitors (nonsteroidal...
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Spatial Metabolomics Reveals the Multifaceted Nature of Lamprey Buccal Gland and Its Diverse Mechanisms for Blood-Feeding
Lampreys are blood-sucking vampires in marine environments. From a survival perspective, it is expected that the lamprey buccal gland exhibits a...
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Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile
Oxylipins are derived from enzymatic and non-enzymatic oxidation of n -3 and n -6 long-chain polyunsaturated fatty acids. They are known to be involved...
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Metabolomics evaluation of the photochemical impact of violet-blue light (405 nm) on ex vivo platelet concentrates
IntroductionMicrobicidal violet-blue light in the visible spectrum (405 nm) has been under evaluation for pathogen inactivation in ex vivo human...
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Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values
BackgroundAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and restricted and...
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In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases
Prostaglandins are important lipids involved in mediating many physiological processes, such as allergic responses, inflammation, and pregnancy....
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A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation
The ketogenic diet (KD) has demonstrated benefits in numerous clinical studies and animal models of disease in modulating the immune response and...
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Contractile Function of the Capsule of the Bovine Mesenteric Lymph Nodes at the Early Stage of Inflammation
AbstractInflammation is detected not only in infections or injuries, but also in many other pathological processes associated with...
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The anti-inflamatory effect of Andira anthelmia lectin in rats involves inhibition of the prostanoid pathway, TNF-α and lectin domain
ObjectiveTo investigate the effect and mechanisms of Andira anthelmia lectin in rat models of acute inflammation.
MaterialAAL anti-inflammatory...
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Lipid mediators in marine diatoms
Diatoms are eukaryotic microalgae representing one of the major groups in the marine phytoplankton, accounting for up to 40% of annual productivity...
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Role of functional fatty acids in modulation of reproductive potential in livestock
Fatty acids are not only widely known as energy sources, but also play important roles in many metabolic pathways. The significance of fatty acids in...
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Prostaglandin E2 receptor Ptger4b regulates female-specific peptidergic neurons and female sexual receptivity in medaka
In vertebrates, female receptivity to male courtship is highly dependent on ovarian secretion of estrogens and prostaglandins. We recently identified...
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Identification and analysis of lipid metabolism-related genes in allergic rhinitis
BackgroundStudies have shown that the lipid metabolism mediator leukotriene and prostaglandins are associated with the pathogenesis of allergic...
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Approaches of estrous synchronization in sheep: developments during the last two decades: a review
The objective of the current review was to summarize the protocols used for estrous synchronization in ewes during the last two decades. Progesterone...
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Resolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice
Severe aplastic anemia (SAA) is a rare, fatal disease characterized by severe cytopenias and loss of hematopoietic stem cells (HSCs). Immune-mediated...
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Development of transgenic mice overexpressing mouse carbonyl reductase 1
BackgroundCarbonyl reductase 1 (CBR1) is a nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reductase with broad substrate specificity....
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Anti-Inflammatory Properties of Metformin During Cultivation of Primary Rat Astrocytes in a Medium with High Glucose Concentration
AbstractInvestigation of the relationship between inflammation and energy metabolism is important for understanding biology of chronic...
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Effects of lead stress on rice (Oryza sativa L.) growth and metabolism in the rhizosphere microenvironment: the role of eicosanoid compounds
As agricultural environments deteriorate, proper management of crop growth and regulation requires an understanding of tolerance strategies to heavy...
