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GNN-Dom: An Unsupervised Method for Protein Domain Partition via Protein Contact Map
Protein domains are the basic building blocks of protein structures, which fold and function independently. Protein domain partition could be used as...
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Maize-legume intercrop** achieves yield advantages by improving leaf functions and dry matter partition
Intercrop** can obtain yield advantages, but the mechanism of yield advantages of maize-legume intercrop** is still unclear. Then, we explored...
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Fruit-Stalk Supplementing Calcium and Partition Regulation of Fruit Calcium for Prevention of Bitter Pit of Bagged Apple
Conventional strategies for the calcium supplementation of apples, such as via direct spray application on the fruit or administering the supplement...
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Evaluating the role of the nuclear microenvironment in gene function by population-based modeling
The nuclear folding of chromosomes relative to nuclear bodies is an integral part of gene function. Here, we demonstrate that population-based...
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Simple separation of glycosphingolipids in the lower phase of a Folch’s partition from crude lipid fractions using zirconium dioxide
A simple method was developed for the separation of glycosphingolipids (GSLs) from lipid mixtures, including phospholipids and cholesterol, using...
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Topologically associating domain boundaries are required for normal genome function
Topologically associating domain (TAD) boundaries partition the genome into distinct regulatory territories. Anecdotal evidence suggests that their...
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ProbPFP: a multiple sequence alignment algorithm combining hidden Markov model optimized by particle swarm optimization with partition function
BackgroundDuring procedures for conducting multiple sequence alignment, that is so essential to use the substitution score of pairwise alignment. To...
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Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals
Concerted robust opening of cardiac ryanodine receptors’ (RyR2) Ca 2+ release 1oplasmic reticulum (SR) is fundamental for normal systolic cardiac...
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Transfer RNA Fragments, from Structure to Function
Transfer RNA molecules (tRNAs) are produced from numerous nuclear and mitochondrial genes and are primarily involved in bringing specific amino acid...
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AnnoPRO: a strategy for protein function annotation based on multi-scale protein representation and a hybrid deep learning of dual-path encoding
Protein function annotation has been one of the longstanding issues in biological sciences, and various computational methods have been developed....
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Complex marine microbial communities partition metabolism of scarce resources over the diel cycle
Complex assemblages of microbes in the surface ocean are responsible for approximately half of global carbon fixation. The persistence of high...
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Modelling von Bertalanffy growth function of fish with fractals
The von Bertalanffy growth function has been widely used by hydrobiologists to study the lifetime pattern of somatic growth in fishes. Recently, the...
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Antipsychotics possess anti-glioblastoma activity by disrupting lysosomal function and inhibiting oncogenic signaling by stabilizing PTEN
The repurposing of medications developed for central nervous system (CNS) disorders, possessing favorable safety profiles and blood-brain barrier...
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Investigating the associations between upper limb motor function and cognitive impairment: a sco** review
Upper limb motor function is a potential new biomarker of cognitive impairment and may aid discrimination from healthy ageing. However, it remains...
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Dual function of a highly conserved bacteriophage tail completion protein essential for bacteriophage infectivity
Infection of bacteria by phages is a complex multi-step process that includes specific recognition of the host cell, creation of a temporary breach...
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A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation
The Hippo pathway has important roles in organ development, tissue homeostasis and tumour growth. Its downstream effector TAZ is a transcriptional...
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Female Germline Cysts in Animals: Evolution and Function
Germline cysts are syncytia formed by incomplete cytokinesis of mitotic germline precursors (cystoblasts) in which the cystocytes are interconnected...
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Structure and function of glycosphingolipids on small extracellular vesicles
Extracellular vesicles (EVs) are membrane-delineated particles secreted by most types of cells under both normal and pathophysiological conditions....
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The Role of Liquid–Liquid Phase Separation in the Structure and Function of Nucleolus
Nucleolus is the largest intracellular membrane-less organelle comprising of proteins, ribosomal RNAs, and small nucleolar RNAs. It had been...