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Schizophyllan promotes osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells in vitro
BackgroundBioactive polysaccharides are a promising way for bone disease prevention with high efficiency. Schizophyllan (SPG) is a polysaccharide...
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Mesenchymal stem cells osteogenic differentiation by ZnO nanoparticles and polyurethane bimodal foam nanocomposites
Mesenchymal stem cells with tissue repair capacity involve in regenerative medicine. MSCs can promote bone repair when employed with nano...
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Passaging of gingival fibroblasts from periodontally healthy and diseased sites upregulates osteogenesis-related genes
To investigate biological processes of the periodontium, in vitro primary cell models have been established. To study the biology of the gingiva,...
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Impairment of 7F2 osteoblast function by simulated partial gravity in a Random Positioning Machine
The multifaceted adverse effects of reduced gravity pose a significant challenge to human spaceflight. Previous studies have shown that bone...
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Osteoporosis and cardiovascular disease: a review
BackgroundOsteoporosis and cardiovascular disease are common diseases encountered globally, especially with advancing age. Osteoporosis occurs when...
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Decellularized leaf-based biomaterial supports osteogenic differentiation of dental pulp mesenchymal stem cells
Decellularized tissues are an attractive scaffolds for 3D tissue engineering. Decellularized animal tissues have certain limitations such as the...
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Vimentin, osteocalcin and osteonectin expression in canine primary bone tumors: diagnostic and prognostic implications
Canine primary bone tumors have a plastic radiographic image, demanding histopathological confirmation. Bone tumors are characterized by the type and...
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Supplementation of Calcium and Fluoride-Free Water Mitigates Skeletal Fluorosis in Fluoride-Intoxicated Rats
Fluorosis is a public health concern in 25 countries around the globe. The present study is about the mitigation of fluoride (F) toxicity by giving...
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Dentine
The dentine, which constitutes most of the tooth, has a resilient structure because it is less dense than enamel. Dentine is synthesized by... -
Evaluation of osteogenic induction potency of miR-27a-3p in adipose tissue-derived human mesenchymal stem cells (AD-hMSCs)
BackgroundBone tissue as a dynamic tissue is able to repair its minor injuries, however, sometimes the repair cannot be completed by itself due to...
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Mesenchymal stem cells encapsulation in chitosan and carboxymethyl chitosan hydrogels to enhance osteo-differentiation
BackgroundRecently biomaterials utilized for designing scaffolds in tissue engineering are not cost-effective and eco-friendly. As a result, we...
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Towards standardization of human adipose-derived stromal cells secretomes
The secretome of adipose-derived stromal cells (ASC) is a heterogeneous mixture of components with a beneficial influence on cellular...
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Pulp
Pulp is a connective tissue surrounded by a dental hard tissue, dentine, and is unique in that it does not permit volume change. Unlike enamel,... -
Mesenchymal stem cells in PRP and PRF containing poly(3-caprolactone)/gelatin Scaffold: a comparative in-vitro study
Scaffold design is one of the three most essential parts of tissue engineering. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have been...
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Osteogenic differentiation of human induced pluripotent stem cell in the presence of testosterone and 17 β-estradiol in vitro
Recently, numerous scientific approaches have been explored to treat various diseases using stem cells. In 2006, induced pluripotent stem cell (iPSC)...
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Polycaprolactone/poly l-lactic acid nanofibrous scaffold improves osteogenic differentiation of the amniotic fluid-derived stem cells
Using stem cells is one of the most important determining factors in repairing lesions using regenerative medicine. Obtaining adult stem cells from...
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The Role of Non-collagenous Proteins and Other Matrix Molecules in Vertebrate Mineralization
The chapter examines the role of non-collagenous proteins, in particular SIBLINGs, evolved from a common gene ancestor, SPARC, in the mineralization... -
The effect of decellularized cartilage matrix scaffolds combined with endometrial stem cell–derived osteocytes on osteochondral tissue engineering in rats
Since decellularized tissues may offer the instructive niche for cell differentiation and function, their use as cell culture scaffolds is a...
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Oral Mucosa and Gingiva
The mucosa, which is composed of epithelium and connective tissue (Fig. 6.1), is a wet membrane covering the inner surface of the body cavity that is... -
G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation
BackgroundThe bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells;...