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Extraction of Mucin from Rodent Feces and Determination of O-Linked Oligosaccharide Chain Equivalent Derived from Fecal Mucin
Since the core protein of mucin in the digesta of the stomach and small intestine, which is less affected by bacteria, remains intact, mucin content...
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Turning the spotlight on the oligosaccharide chain of GM1 ganglioside
It is well over a century that glycosphingolipids are matter of interest in different fields of research. The hydrophilic oligosaccharide and the...
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Topological and enzymatic analysis of human Alg2 mannosyltransferase reveals its role in lipid-linked oligosaccharide biosynthetic pathway
N-glycosylation starts with the biosynthesis of lipid-linked oligosaccharide (LLO) on the endoplasmic reticulum (ER). Alg2 mannosyltransferase adds...
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Novel β1,4 N-acetylglucosaminyltransferase in de novo enzymatic synthesis of hyaluronic acid oligosaccharides
AbstractThe efficiency of de novo synthesis of hyaluronic acid (HA) using Pasteurella multocida hyaluronate synthase (PmHAS) is limited by its low...
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GM1 structural requirements to mediate neuronal functions
Since the 1980s, it has been known that the administration of ganglioside GM1 to cultured cells induced or enhanced neuronal differentiation. GM1...
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Experimental and computational characterization of dynamic biomolecular interaction systems involving glycolipid glycans
On cell surfaces, carbohydrate chains that modify proteins and lipids mediate various biological functions, which are exerted not only through...
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Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor
Conotoxins are marine peptide toxins from marine cone snails. The α-conotoxin RegIIA can selectively act on human (h) α3β4 nicotinic acetylcholine...
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Aureolic Acid-Derived Antibiotics: Prospects for a Biologically Active Class
AbstractAureolic acid-derived antibiotics such as mithramycin, chromomycin A3, and olivomycin А, are aromatic glycosylated polyketides produced by...
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Glycosylation in Eukaryotes
In eukaryotes from lower molds to terminally evolved humans, distinct biological event is so called glycosylation. Therefore, cell-specific and...
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Cell Wall Galactofuranans and Galactomannan as Chemotaxonomic Characteristics of the Clavibacter Genus and its Species
AbstractTwo types of cell wall glycopolymers of different structure were found in the type strains of two species of phytopathogenic bacteria, Claviba...
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Priestia flexa KS1: A new bacterial strain isolated from human faeces implicated in mucin degradation
The human gut acts as a habitat for diverse microbial communities, including mucin utilizers that play a significant role in host health and...
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Acid hydrolysis of spent coffee grounds: effects on possible prebiotic activity of oligosaccharides
BackgroundSpent coffee grounds (SCG) are a promising source of natural by-products which can be used for different purposes. In this work, a possible...
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Ruminal bacteria lipopolysaccharides: an immunological and microbial outlook
Lipopolysaccharides (LPS) are outer membrane components of Gram-negative bacteria made of three regions: the O-antigen; the core oligosaccharide; and...
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Structures of the xyloglucans in the monocotyledon family Araceae (aroids)
Main conclusionThe xyloglucans of all aquatic Araceae species examined had unusual structures compared with those of other non-commelinid...
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Preparation of Mucin Glycopeptides by Organic Synthesis
Mucins are sugar-rich glycoproteins. Glycoprotein sugar moieties are structurally diverse, making it difficult to obtain naturally pure...
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Lipopolysaccharide O-antigen profiles of Helicobacter pylori strains from Southwest China
BackgroundHelicobacter pylori lipopolysaccharide (LPS) structures vary among strains of different geographic origin. The aim of this study was to...
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Structural and biochemical insight into a modular β-1,4-galactan synthase in plants
Rhamnogalacturonan I (RGI) is a structurally complex pectic polysaccharide with a backbone of alternating rhamnose and galacturonic acid residues...
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Synthesis of 2′-fucosyllactose from apple pomace–derived xyloglucan oligosaccharides by an α-L-fucosidase from Pedobacter sp. CAU209
Abstract2′-Fucosyllactose (2′-FL) is known for its ability to provide various health benefits to infants, such as gut maturation, pathogen...
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Enzymatic Sequencing of Heparin Oligosaccharides Using Exolyase
Heparin/heparan sulfate (HP/HS) is a class of acidic polysaccharides with many potential medical applications, especially HP, and its derivatives,...
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Structural characterization of water-soluble polysaccharides isolated from leaves of Hedera nepalensis
BackgroundHedera nepalensis is a traditional medicinal plants, and the dried leaves of it are generally used for the cure and treatment of many...
