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Functional cargos of exosomes derived from Flk-1+ vascular progenitors enable neurulation and ameliorate embryonic anomalies in diabetic pregnancy
Various types of progenitors initiate individual organ formation and their crosstalk orchestrates morphogenesis for the entire embryo. Here we show...
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Hallmarks of primary neurulation are conserved in the zebrafish forebrain
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural plate. Incomplete neural...
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In Vivo Analysis of the Mesenchymal-to-Epithelial Transition During Chick Secondary Neurulation
The neural tube in amniotic embryos forms as a result of two consecutive events along the anteroposterior axis, referred to as primary and secondary...
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Wnt/planar cell polarity signaling controls morphogenetic movements of gastrulation and neural tube closure
Gastrulation and neurulation are successive morphogenetic processes that play key roles in sha** the basic embryonic body plan. Importantly, they...
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Embryonic exposure to decitabine induces multiple neural tube defects in develo** zebrafish
Neural tube defects are severe congenital disorders of the central nervous system that originate during embryonic development when the neural tube...
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Assays for Apical Constriction Using the Xenopus Model
Apical constriction refers to the active, actomyosin-driven process that reduces apical cell surface area in epithelial cells. Apical constriction is...
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Expression of polyamines and its association with GnRH-I in the hypothalamus during aging in rodent model
GnRH-I and GnIH are the key neuropeptides that regulate the hypothalamic–pituitary–gonadal axis in mammals during aging. Polyamines are important...
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The role of prickle proteins in vertebrate development and pathology
Prickle is an evolutionarily conserved family of proteins exclusively associated with planar cell polarity (PCP) signalling. This signalling pathway...
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Hybridization barriers between the congeneric antarctic notothenioid fish Notothenia coriiceps and Notothenia rossii
Hybridization between species and the establishment of hybridization barriers can influence the diversification of species. Antarctic notothenioid...
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Development Features on the Selection of Animal Models for Teratogenic Testing
Today, the use of animal models from different species continues to represent a fundamental step in teratogenic testing, despite the increase in...
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The Cambrian fossil Pikaia, and the origin of chordate somites
The Middle Cambrian fossil Pikaia has a regular series of vertical bands that, assuming chordate affinities, can be interpreted as septa positioned...
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Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness
Individual cell shape and integrity must precisely be orchestrated during morphogenesis. Here, we determine function of type II cadherins, Cdh6, Cdh8 ,...
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Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice
Backgroundp120 catenin (p120ctn) is an important component in the cadherin-catenin cell adhesion complex because it stabilizes cadherin-mediated...
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Ubiquitin ligases: guardians of mammalian development
Mammalian development demands precision. Millions of molecules must be properly located in temporal order, and their function regulated, to...
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Post-implantation Embryo Development in the South American Plains Vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)
The early embryo development after implantation varies among mammals. In muroid rodents, an egg cylinder is formed by folding during gastrulation;...
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Lamprey as Laboratory Model for Study of Molecular Bases of Ontogenesis and Evolutionary History of Vertebrata
AbstractThe basic knowledge about the development and formation of the body plan of vertebrates (Vertebrata) was obtained while working with...
