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Omi inhibition ameliorates neuron apoptosis and neurological deficit after subarachnoid hemorrhage in rats
BackgroundSubarachnoid hemorrhage (SAH) is a severe neurological emergency, resulting in cognitive impairments and threatening human's health....
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Signal Transduction Associated with Mn-induced Neurological Dysfunction
Manganese (Mn) is a heavy metal that occurs widely in nature and has a vital physiological role in growth and development. However, excessive...
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Drosophila olfaction as a model system for studying human neurological disorders
The fruit fly, Drosophila melanogaster , has been one of the finest systems for decoding myriad puzzles across different domains of biology. Beyond...
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De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor
N-methyl- d -aspartate receptors (NMDARs) are members of the glutamate receptor family and participate in excitatory postsynaptic transmission...
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The role of Smo-Shh/Gli signaling activation in the prevention of neurological and ageing disorders
Sonic hedgehog (Shh) signaling is an essential central nervous system (CNS) pathway involved during embryonic development and later life stages....
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Iron Deficiency Anemia Is Associated with Proprioceptive Deficit in Adult Women: a Cross-Sectional Case–Control Study
Proprioception is essential to several conscious and unconscious sensations and automatic control of movement in daily life activities. Iron...
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Neurological Effects of Cannabis
Cannabis products and Cannabis use are inherently variable. Given the difficulty in standardizing Cannabis products and Cannabis use patterns,...
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A Mini Review on the Various Facets Effecting Brain Delivery of Magnesium and Its Role in Neurological Disorders
Magnesium is an essential cation present in the body that participates in the regulation of various vital body functions. Maintaining normal level of...
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Data-driven health deficit assessment improves a frailty index’s prediction of current cognitive status and future conversion to dementia: results from ADNI
Frailty is a dementia risk factor commonly measured by a frailty index (FI). The standard procedure for creating an FI requires manually selecting...
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Dexmedetomidine alleviates cerebral ischemia-reperfusion injury via inhibiting autophagy through PI3K/Akt/mTOR pathway
Dexmedetomidine has been shown to protect against cerebral ischemia-reperfusion injury (CIRI). Nevertheless, the precise mechanism is obscure. In...
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Bone marrow-derived mesenchymal stem cells improve post-ischemia neurological function in rats via the PI3K/AKT/GSK-3β/CRMP-2 pathway
Background: Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) is a potential therapy for cerebral ischemia. However, the...
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Intracerebroventricular Administration of hNSCs Improves Neurological Recovery after Cardiac Arrest in Rats
Irreversible brain injury and neurological dysfunction induced by cardiac arrest (CA) have long been a clinical challenge due to lack of effective...
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Critical Neurological Conditions: Severe Toxic Polyneuropathy with the Development of Respiratory Failure and Rhabdomyolysis
AbstractThe article describes the clinical case of severe toxic polyneuropathy due to a confirmed exogenous intoxication with amphetamine in a...
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A Brief Review on Erythropoietin and Mesenchymal Stem Cell Therapies for Paediatric Neurological Disorders
Purpose of ReviewPaediatric neurological disorders (PNDs) are neurological conditions in infants resulting from injury to the develo** nervous...
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Pre exposure to enriched environment alleviates brain injury after ischemia-reperfusion by inhibiting p38MAPK/STAT1 pathway
BackgroundStroke is one of the major diseases that endangers human health. It is widely reported that enriched environment (EE) can improve the...
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A preliminary study on the effects of **aoyao San on neurological function and 5-HT2A mRNA expression in mice with Tourette syndrome
BackgroundTourette syndrome (TS) is a chronic neuropsychiatric disorder, also known as multiple tic syndrome. TS is associated with the serotonin...
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Inhibition of perilipin 2 attenuates cerebral ischemia/reperfusion injury by blocking NLRP3 inflammasome activation both in vivo and in vitro
Cerebral ischemia/reperfusion (CI/R) usually causes neuroinflammation within the central nervous system, further prompting irreversible cerebral...
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Combined treatment of nerve growth factor and transcranical direct current stimulations to improve outcome in children with vegetative state after out-of-hospital cardiac arrest
BackgroundOut-of-hospital cardiac arrest (OHCA) is one of the most dramatic events in pediatric age and, despite advanced neurointensive care, the...
