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  1. Emergence and maintenance of stable coexistence during a long-term multicellular evolution experiment

    The evolution of multicellular life spurred evolutionary radiations, fundamentally changing many of Earth’s ecosystems. Yet little is known about how...

    Rozenn M. Pineau, Eric Libby, ... William C. Ratcliff in Nature Ecology & Evolution
    Article 14 March 2024
  2. Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids

    Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with respect to more traditional 2D culturing. Microwell culturing...

    Ottavia Tartagni, Alexandra Borók, ... Giampaolo Zuccheri in Cellular and Molecular Life Sciences
    Article Open access 16 March 2023
  3. Distinct types of multicellular aggregates in Pseudomonas aeruginosa liquid cultures

    Pseudomonas aeruginosa forms suspended multicellular aggregates when cultured in liquid media. These aggregates may be important in disease, and/or...

    Gavin Melaugh, Vincent A. Martinez, ... Rosalind J. Allen in npj Biofilms and Microbiomes
    Article Open access 28 July 2023
  4. Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems

    Background

    The Biology System Description Language (BiSDL) is an accessible, easy-to-use computational language for multicellular synthetic biology....

    Leonardo Giannantoni, Roberta Bardini, ... Stefano Di Carlo in BMC Bioinformatics
    Article Open access 25 April 2024
  5. Open-top multisample dual-view light-sheet microscope for live imaging of large multicellular systems

    Multicellular systems grow over the course of weeks from single cells to tissues or even full organisms, making live imaging challenging. To bridge...

    Franziska Moos, Simon Sup**er, ... Prisca Liberali in Nature Methods
    Article Open access 20 March 2024
  6. Looking outside the box: a comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life

    Many cell biological facts that can be found in dedicated scientific textbooks are based on findings originally made in humans and/or other mammals,...

    Ralph Panstruga, Wolfram Antonin, Alexander Lichius in Cellular and Molecular Life Sciences
    Article Open access 07 July 2023
  7. Aging is a Side Effect of the Ontogenesis Program of Multicellular Organisms

    Abstract

    The review presents a brief outline of the current state of the main theoretical approaches to the aging problem. The works of authors,...

    Lev Salnikov in Biochemistry (Moscow)
    Article Open access 01 December 2022
  8. Multicellular Morphogenesis

    Multicellular morphogenesis is responsible for generating most living forms in the world around us and lays the structural basis for these forms’...
    Chapter 2021
  9. Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular origins

    Background

    Metazoans inherited genes from unicellular ancestors that perform essential biological processes such as cell division, metabolism, and...

    Anna S. Trigos, Felicia Bongiovanni, ... David L. Goode in Genome Biology
    Article Open access 29 April 2024
  10. Multicellular Organisms and Their Development

    We will start here by considering some features of the cellular structure of tissues and the connections between the cells there. All different cells...
    Alexander Vologodskii in The Basics of Molecular Biology
    Chapter 2023
  11. Cryopreservation of two species of the multicellular volvocine green algal genus Astrephomene

    Background

    Astrephomene is an interesting green algal genus that, together with Volvox , shows convergent evolution of spheroidal multicellular bodies...

    Hisayoshi Nozaki, Fumi Mori, ... Masanobu Kawachi in BMC Microbiology
    Article Open access 18 January 2023
  12. Why have aggregative multicellular organisms stayed simple?

    Multicellularity has evolved numerous times across the tree of life. One of the most fundamental distinctions among multicellular organisms is their...

    Pedro Márquez-Zacarías, Peter L. Conlin, ... William C. Ratcliff in Current Genetics
    Article 10 June 2021
  13. Translation stalling proline motifs are enriched in slow-growing, thermophilic, and multicellular bacteria

    Rapid bacterial growth depends on the speed at which ribosomes can translate mRNA into proteins. mRNAs that encode successive stretches of proline...

    Tess E. Brewer, Andreas Wagner in The ISME Journal
    Article 25 November 2021
  14. Tonian carbonaceous compressions indicate that Horodyskia is one of the oldest multicellular and coenocytic macro-organisms

    Macrofossils with unambiguous biogenic origin and predating the one-billion-year-old multicellular fossils Bangiomorpha and Proterocladus interpreted...

    Guang** Li, Lei Chen, ... Shuhai **ao in Communications Biology
    Article Open access 12 April 2023
  15. Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity

    Biofilms are organised heterogeneous assemblages of microbial cells that are encased within a self-produced matrix. Current estimates suggest that up...

    Anahit Penesyan, Ian T. Paulsen, ... Michael R. Gillings in npj Biofilms and Microbiomes
    Article Open access 10 November 2021
  16. A 3D Multicellular Simulation Layer for the Synthetic Biology CAD Infobiotics Workbench Suite

    Although computational solutions are commonplace in Synthetic Biology laboratories that use software, proprietary or otherwise, the use of...
    Richard Oliver Matzko, Laurentiu Mierla, Savas Konur in Bioinformatics and Biomedical Engineering
    Conference paper 2022
  17. Studying the Organization of the Actin Cytoskeleton in the Multicellular Trichomes of Tomato

    Trichomes are unique polarized cells of the plant epidermis that provide an excellent model system for studying the plant cytoskeleton. Unlike...
    Zhi**g Xu, **aolu Qu, ... Pengwei Wang in The Plant Cytoskeleton
    Protocol 2023
  18. Cryopreservation of vegetative cells and zygotes of the multicellular volvocine green alga Gonium pectorale

    Background

    Colonial and multicellular volvocine green algae have been extensively studied recently in various fields of the biological sciences....

    Hisayoshi Nozaki, Fumi Mori, ... Masanobu Kawachi in BMC Microbiology
    Article Open access 14 April 2022
  19. Hidden paths to endless forms most wonderful: ecology latently shapes evolution of multicellular development in predatory bacteria

    Ecological causes of developmental evolution, for example from predation, remain much investigated, but the potential importance of latent phenotypes...

    Marco La Fortezza, Olaya Rendueles, ... Gregory J. Velicer in Communications Biology
    Article Open access 16 September 2022
  20. Extracellular lipopeptide bacillomycin L regulates serial expression of genes for modulating multicellular behavior in Bacillus velezensis Bs916

    In wild strains of Bacillus , a handful of extracellular natural products act as signals that can regulate multicellular behavior, but relatively...

    Chu** Luo, Jiachen Liu, ... Bin Li in Applied Microbiology and Biotechnology
    Article 03 September 2021
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