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Emergence and maintenance of stable coexistence during a long-term multicellular evolution experiment
The evolution of multicellular life spurred evolutionary radiations, fundamentally changing many of Earth’s ecosystems. Yet little is known about how...
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Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids
Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with respect to more traditional 2D culturing. Microwell culturing...
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Distinct types of multicellular aggregates in Pseudomonas aeruginosa liquid cultures
Pseudomonas aeruginosa forms suspended multicellular aggregates when cultured in liquid media. These aggregates may be important in disease, and/or...
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Biology System Description Language (BiSDL): a modeling language for the design of multicellular synthetic biological systems
BackgroundThe Biology System Description Language (BiSDL) is an accessible, easy-to-use computational language for multicellular synthetic biology....
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Open-top multisample dual-view light-sheet microscope for live imaging of large multicellular systems
Multicellular systems grow over the course of weeks from single cells to tissues or even full organisms, making live imaging challenging. To bridge...
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Looking outside the box: a comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life
Many cell biological facts that can be found in dedicated scientific textbooks are based on findings originally made in humans and/or other mammals,...
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Aging is a Side Effect of the Ontogenesis Program of Multicellular Organisms
AbstractThe review presents a brief outline of the current state of the main theoretical approaches to the aging problem. The works of authors,...
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Multicellular Morphogenesis
Multicellular morphogenesis is responsible for generating most living forms in the world around us and lays the structural basis for these forms’... -
Disruption of metazoan gene regulatory networks in cancer alters the balance of co-expression between genes of unicellular and multicellular origins
BackgroundMetazoans inherited genes from unicellular ancestors that perform essential biological processes such as cell division, metabolism, and...
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Multicellular Organisms and Their Development
We will start here by considering some features of the cellular structure of tissues and the connections between the cells there. All different cells... -
Cryopreservation of two species of the multicellular volvocine green algal genus Astrephomene
BackgroundAstrephomene is an interesting green algal genus that, together with Volvox , shows convergent evolution of spheroidal multicellular bodies...
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Why have aggregative multicellular organisms stayed simple?
Multicellularity has evolved numerous times across the tree of life. One of the most fundamental distinctions among multicellular organisms is their...
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Translation stalling proline motifs are enriched in slow-growing, thermophilic, and multicellular bacteria
Rapid bacterial growth depends on the speed at which ribosomes can translate mRNA into proteins. mRNAs that encode successive stretches of proline...
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Tonian carbonaceous compressions indicate that Horodyskia is one of the oldest multicellular and coenocytic macro-organisms
Macrofossils with unambiguous biogenic origin and predating the one-billion-year-old multicellular fossils Bangiomorpha and Proterocladus interpreted...
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Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity
Biofilms are organised heterogeneous assemblages of microbial cells that are encased within a self-produced matrix. Current estimates suggest that up...
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A 3D Multicellular Simulation Layer for the Synthetic Biology CAD Infobiotics Workbench Suite
Although computational solutions are commonplace in Synthetic Biology laboratories that use software, proprietary or otherwise, the use of... -
Studying the Organization of the Actin Cytoskeleton in the Multicellular Trichomes of Tomato
Trichomes are unique polarized cells of the plant epidermis that provide an excellent model system for studying the plant cytoskeleton. Unlike... -
Cryopreservation of vegetative cells and zygotes of the multicellular volvocine green alga Gonium pectorale
BackgroundColonial and multicellular volvocine green algae have been extensively studied recently in various fields of the biological sciences....
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Hidden paths to endless forms most wonderful: ecology latently shapes evolution of multicellular development in predatory bacteria
Ecological causes of developmental evolution, for example from predation, remain much investigated, but the potential importance of latent phenotypes...
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Extracellular lipopeptide bacillomycin L regulates serial expression of genes for modulating multicellular behavior in Bacillus velezensis Bs916
In wild strains of Bacillus , a handful of extracellular natural products act as signals that can regulate multicellular behavior, but relatively...