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Determining Macromolecular Structures Using Cryo-Electron Microscopy
Structural insights into macromolecular and protein complexes provide key clues about the molecular basis of the function. Cryogenic electron...
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X-Ray Crystallography for Macromolecular Complexes
X-ray crystallography has for most of the last century been the standard technique to determine the high-resolution structure of biological...
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Evaluating β-cryptoxanthin antioxidant properties against ROS-induced macromolecular damages and determining its photo-stability and in-vitro SPF
Natural antioxidants have become vital to minimize macromolecular damage caused by Reactive Oxygen Species (ROS). This study investigated the...
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Macromolecular crowding facilitates rapid fabrication of intact, robust cell sheets
ObjectivesTo develop a rapid and simple method to fabricate intact, robust cell sheets from common cell culture dishes by combination of a...
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A comprehensive approach to phytochemical analysis of macromolecular composites that protect tubers: case studies in suberized potato periderm tissues
Terrestrial plants rely on protection conferred by their outer coverings to defend against desiccation, bruising, and microbial invasion. For food...
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Ocean warming and acidification affect the transitional C:N:P ratio and macromolecular accumulation in the harmful raphidophyte Heterosigma akashiwo
Despite an increase in ocean warming and acidification that is expected to increase the number of harmful algal species worldwide, the population of...
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Features of Synthesis and Antimicrobial Properties of Guanidine-Containing Carboxymethylcellulose Derivatives
AbstractThe article presents data on the synthesis and antimicrobial properties of guanidine-containing carboxymethylcellulose derivatives with...
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1 Phospholipid synthesis in mammalian cells
Phospholipids are the main components of biological membranes and as such act as the major permeability barrier between cells and the extracellular...
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GmHXK2 promotes the salt tolerance of soybean seedlings by mediating AsA synthesis, and auxin synthesis and distribution
BackgroundSalt is an important factor that affects crop productivity. Plant hexokinases (HXKs) are key enzymes in the glycolytic pathway and sugar...
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Adipose-derived stromal cells increase the formation of collagens through paracrine and juxtacrine mechanisms in a fibroblast co-culture model utilizing macromolecular crowding
BackgroundAdipose-derived stromal cells (ASCs) possess a multitude of regenerative capabilities, which include immunomodulation, angiogenesis, and...
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Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP/PKA signaling pathway
Estrogen excess in females has been linked to a diverse array of chronic and acute diseases. Emerging research shows that exposure to estrogen-like...
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Assessment of intestinal macromolecular absorption in young piglets to pave the way to oral vaccination: preliminary results
The small intestine of the piglet has evolved to be permeable immediately after birth to facilitate the uptake of colostrum-derived immunoglobulins...
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Characterization of Complexes and Supramolecular Structures by Electron Microscopy
Recent advancements in cryo-electron microscopy (cryo-TEM) have enabled the determination of structures of macromolecular complexes at near-atomic...
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Genome-wide identification of polyamine metabolism and ethylene synthesis genes in Chenopodium quinoa Willd. and their responses to low-temperature stress
BackgroundQuinoa ( Chenopodium quinoa Willd.) is valued for its nutritional richness. However, pre-harvest sprouting poses a significant threat to...
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Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae
BackgroundIn fast-growing bacteria, the genomic location of ribosomal protein (RP) genes is biased towards the replication origin ( oriC ). This trait...
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Synthesis and Anti-Mycobacterium Activity of Some New N-Rich Heterocyclic Derivatives and Their Molecular Docking, and DFT Studies
AbstractObjective: Synthesis of N -rich heterocyclic derivatives; anti-TB activity, molecular docking, ADME-T, and computational studies. Methods: ...
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Optimizing the synthesis of dimeric peptides: influence of the reaction medium and effects that modulate kinetics and reaction yield
Peptides are remarkably interesting alternatives to several applications. In particular, antimicrobial sequences have raised major interest of the...
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Regulation of T3SS synthesis, assembly and secretion in Pseudomonas aeruginosa
T3SS is an important virulence factor of Pseudomonas aeruginosa and has a central role in the infection process. However, the functional regulation...
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Advancement in Nanomaterial Synthesis and its Biomedical Applications
Infections have been the greatest challenge to the advancement of human race. With the advent of antibiotic therapy, successful treatment strategy...
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Multi-omic analysis reveals the effects of interspecific hybridization on the synthesis of seed reserve polymers in a Triticum turgidum ssp. durum × Aegilops sharonensis amphidiploid
BackgroundWheat grain endosperm is mainly composed of proteins and starch. The contents and the overall composition of seed storage proteins (SSP)...
