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The MTT Assay: A Method for Error Minimization and Interpretation in Measuring Cytotoxicity and Estimating Cell Viability
The MTT assay is extensively used, most often to infer a measure of cytotoxicity of treatments to cells. As with any assay though, there are a number...
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Screening for Antiviral Activity: MTT Assay
To evaluate the efficiency of the actinobacterial extract, a precise and reliable method was developed against dengue virus, based on the...
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In Vitro Cytotoxicity Analysis: MTT/XTT, Trypan Blue Exclusion
In vitro cytotoxicity analyses have played a major role in the current drug discovery processes. These analyses enable the measurement of target cell...
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Screening for Anticancer Activity: 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium (MTT) Assay
A potential barrier to clinical treatment is the discovery of anticancer drugs that destroy or disable tumor cells in the presence of normal cells...
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Calcium hypochlorite on mouse embryonic fibroblast cells (NIH3T3) in vitro cytotoxicity and genotoxicity: MTT and comet assay
Antimicrobial irrigation solutions are widely used under clinical settings. Their effect on dental tissue is a subject of recent research, which aims...
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Cytotoxicity Assay
Cytotoxicity test is defined as the screening test and biological evaluation of tissue cells in vitro to detect the growth, the reproduction, and...
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Phenotypical Method
To better apply bacteriocins in the field of biotechnology, it is particularly important to study their phenotypic characteristics. This chapter...
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Design, Drug-Likeness, Synthesis, Characterization, Antimicrobial Activity, Molecular Docking, and MTT Assessment of 1,3-Thiazolidin-4-one Bearing Piperonal and Pyrimidine Moieties
Abstract —The recent study reported the designing of substituted...
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In Vitro Assay for Determining Cyanotoxin Using Cell Line Method: Hepatotoxicity (Cell Lines—HepG2, Caco-2, and V79)
Harmful cyanobacterial blooms are increasing and becoming a worldwide concern as many bloom-forming cyanobacterial species can produce toxic...
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The effects of Quercetin on wound healing in the human umbilical vein endothelial cells
An injury that affects the integrity of the skin, either inside or externally, is called a wound. Damaged tissue is repaired by a set of cellular and...
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Screening of Actinobacterial Probiotics by Anti-Pathogenic Activity Test
Actinomycetes, which can produce various metabolites and exert antibacterial effects, have been used as probiotics in aquaculture, poultry, and...
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Isolation and Characterization of Extracellular Vesicles of Chick Embryo Blood
Exosomes from plants or animals are a cheap, available, and promising option in medicine, which can be used for the detection or treatment of various...
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Assessment of the Toxic Effect of 2-(Chlorodinitromethyl)-4-Methoxy-6-(4-Methylpiperazine-1-yl)-1,3,5-Triazine by Respiratory Activity of Lymphocytes
Abstract —A method for evaluation of metabolic characteristics of intact cells based on electrochemical registration of their respiratory activity was...
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Inhibition of Liver Cancer Cell Viability by Triazole through Up-regulation of p38 Phosphorylation and Targeting the Activation of p-ERK1/2 and Akt Protein Expression
AbstractThe present study was aimed to explore the effect of triazole on growth and viability of liver cancer cells. Cell growth was examined using...
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Assessment of viability in coral oocytes: a biochemical approach to achieve reliable assays
Given the current threatening scenario faced by coral reefs, reproductive biotechnologies can be a hel** hand in the fight against extinction....
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Inhibition of PI3K/AKT signaling using BKM120 reduced the proliferation and migration potentials of colorectal cancer cells and enhanced cisplatin-induced cytotoxicity
BackgroundAlthoughextensive efforts have been made to improve the treatment of colorectal cancer (CRC) patients, the prognosis for these patients...
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Separate and Mutual Effects of BIRB796 and Bortezomib on pHsp27 and Viability of U87MG Glioma Cells
AbstractHsp27 phosphorylation is associated with many pathways in glioma, such as tumor cell proliferation and apoptosis inhibition. The aim of this...
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The impact of exosomes derived from B-cell acute lymphoblastic leukemia as a growth factor on bone marrow mesenchymal stromal cells
Background The incidence of various types of cancers, including leukemia, is on the rise and many challenges in both drug resistance and...
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Determination of anti-cancer effects of Nigella sativa seed oil on MCF7 breast and AGS gastric cancer cells
BackgroundThis study aimed to investigate the cytotoxic, apoptotic, invasion, metastasis, and heat shock proteins (HSPs) effects of N. sativa oil on...
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The potential therapeutic effect of melatonin in oxaliplatin combination therapy against chemoresistant colorectal cancer cells
BackgroundOxaliplatin is one of the main therapeutics in colorectal cancer (CRC) chemotherapy. However, in light of multidrug resistance (MDR)...
