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Investigation of the Effect of Tamoxifen on hERG1 Potassium Channel Gene Expression in MCF-7 Cell Line
AbstractObjective: Tamoxifen (TAM) is a nonstreroidal antiestrogenic pharmaceutical agent extensively employed in the therapeutic management of...
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Cytotoxic and Photosensitizing Properties of Lichen Extracts in Relation to the Human Tumor Cell Line (MCF-7)
AbstractThe ability of the thirty-five extracts from five common lichen species in Belarus to correct the viability of the MCF-7 human carcinoma line...
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Gaillardin inhibits autophagy and induces apoptosis in MCF-7 breast cancer cells by regulating JAK/STAT pathway
BackgroundGaillardin is a potent anti-cancer sesquiterpene lactone found in Inula oculus-christi .
AimThe present study examined the effects of...
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Quantitative analysis of biochemical characteristics and anti-cancer properties in MCF-7 breast cancer cell line: a comparative study between Ziziphus jujube honey and commercial honey
BackgroundThere is increasing evidence that honey has anti-inflammatory, antioxidant, and anti-cancer effects. This study aims to assess and contrast...
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Anticarcinogenic Effects of Gold Nanoparticles and Metformin Against MCF-7 and A549 Cells
Metformin is commonly prescribed to people with diabetes. Metformin has been shown in previous studies to be able to prevent the growth of cancer...
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Titanium-Dioxide Nanoparticles Suppress Entosis in MCF-7 Human Breast Adenocarcinoma Culture
AbstractTiO 2 nanoparticles are widely used in industry, pharmacology, and medicine. Recently, it has been proposed to use TiO 2 nanoparticles for...
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Cytotoxicity of bismuth(III) dithiocarbamate derivatives by promoting a mitochondrial-dependent apoptotic pathway and suppressing MCF-7 breast adenocarcinoma cell invasion
We previously reported that the bismuth(III) dithiocarbamate derivative, bismuth diethyldithiocarbamate ( 1 ) exhibited greater cytotoxicity while...
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Differential DNA methylation and CTCF binding between the ESR1 promoter a of MCF-7 and MDA-MB-231 breast cancer cells
BackgroundESR1 is expressed by 60–70% of breast tumours. it’s a good prognosis factor and the target of hormone therapy. Optimization of ESR1...
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Minocycline induced apoptosis and suppressed expression of matrix metalloproteinases 2 and 9 in the breast cancer MCF-7 cells
BackgroundIn women, breast cancer is the second most frequent type of cancer. Looking for new and effective cancer-specific therapies with little to...
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Effects of Juglone and Curcumin Administration on Expression of FABP5 and FABP9 in MCF-7 and MDA-MB-231 Breast Cancer Cell Lines
Abstract —Among natural chemopreventive agents, polyphenol curcumin and naphthoquinone juglone, which has broad-spectrum anticancer activity, are...
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Selective and oxidative stress-mediated cell death of MCF-7 cell line induced by terpinolene
In this study, we compared the effects of terpinolene against the anti-cancer agent cisplatin on proliferation, apoptotic activity and intracellular...
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Investigation of HER-3 gene expression under the influence of carbohydrate biopolymers extract of shiitake and reishi in MCF-7 cell line
IntroductionEdible-medicinal fungi are mainly used in Asian countries to prevent various diseases. These mushrooms are also used to treat lung...
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Fusaric acid inhibits proliferation and induces apoptosis through triggering endoplasmic reticulum stress in MCF-7 human breast cancer cells
Breast cancer has replaced lung cancer to be the leading cancer in the world. Currently, chemotherapy is still the major method for breast cancer...
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Apoptosis Induction by ZnFe2O4-Ag Biosynthesized by Chlorella vulgaris in MCF-7 Breast Cancer Cell Line
The incidence and mortality of breast cancer are growing which indicates the inefficiency of the current chemotherapy drugs. Due to the anticancer...
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The combined restoration of miR-424-5p and miR-142-3p effectively inhibits MCF-7 breast cancer cell line via modulating apoptosis, proliferation, colony formation, cell cycle and autophagy
BackgroundThe combined restoration of tumor-suppressive microRNAs (miRs) has been identified as a promising approach for inhibiting breast cancer...
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Does Boric Acid Inhibit Cell Proliferation on MCF-7 and MDA-MB-231 Cells in Monolayer and Spheroid Cultures by Using Apoptosis Pathways?
Most breast cancers originate in the lobules or ducts of the breast. Breast cancer as the second main cause of death among women in the world is the...
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Increasing the Radiosensitivity of MCF-7 Cancer Stem Cells Cultivated as Mammospheres to γ- and γ-Neutron Irradiation with Metformin
AbstractCancer stem cells (CSCs) are highly resistant to chemo- and radiotherapy. The aim of this work was to study the effect of metformin on the...
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Unveiling the therapeutic potential of thymol from Nigella sativa L. seed: selective anticancer action against human breast cancer cells (MCF-7) through down-regulation of Cyclin D1 and proliferative cell nuclear antigen (PCNA) expressions
BackgroundBreast adenocarcinoma cells (MCF-7) are characterized by the overexpression of apoptotic marker genes and proliferative cell nuclear...
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Design anticancer potential of Zn(II)isoleucinedithiocarbamate complex on MCF-7 cell lines: synthesis, characterization, molecular docking, molecular dynamic, ADMET, and in-vitro studies
Cisplatin is a cancer medication widely used today, but it still poses some problems due to its toxic properties in the body. To overcome this issue,...
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Enhanced Induction of Apoptosis and Cell Cycle Arrest in MCF-7 Breast Cancer and HT-29 Colon Cancer Cell Lines via Low-Dose Biosynthesis of Selenium Nanoparticles Utilizing Lactobacillus casei
As a leading global cause of mortality, cancer continues to pose a significant challenge. The shortcomings of prevalent cancer treatments, such as...
