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Genomic survey of high-throughput RNA-Seq data implicates involvement of long intergenic non-coding RNAs (lincRNAs) in cytoplasmic male-sterility and fertility restoration in pigeon pea
BackgroundLong-intergenic non-coding RNAs (lincRNAs) originate from intergenic regions and have no coding potential. LincRNAs have emerged as key...
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Long Intergenic Noncoding RNA (lincRNA) Discovery from Non-Strand-Specific RNA-Seq Data
Long noncoding RNAs (lncRNAs) are transcripts over 200 base pairs in length without discernible protein coding potential. Long intergenic noncoding...
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Long non-coding RNA variability in porcine skeletal muscle
Recently, numerous studies including various tissues have been carried out on long non-coding RNAs (lncRNAs), but still, its variability has not yet...
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Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis
BackgroundLong intergenic non-coding RNA 326 (LINC00326) modulates hepatocarcinogenic lipid metabolism. However, the ability of LINC00326 to modulate...
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Role of Bioinformatics in Non-coding RNA Analysis
The transcriptome, comprising RNA molecules expressed in cells or tissues, is predominantly composed of non-coding RNAs (ncRNAs), which has most of...
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Long intergenic non-protein coding RNA 467 inhibition elevates microRNA-27b-3p to repress malignant behaviors of gastric cancer cells via reducing STAT3
Emerging evidence indicated that long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) exert critical effects on tumorigenesis of multiple...
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Long intergenic non-protein coding RNA 1436 accelerates cell proliferation, migration and adhesion properties of the MUM-2B cell line via microRNA-513a-5p/CUG Triplet repeat-binding protein 1 axis to activate the phosphatidylinositol 3-kinase/Akt signaling pathway
ObjectiveLong intergenic non-protein coding RNA 1436 (LINC01436) has been reported as a critical regulator of tumor occurrence, but the association...
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A long non-coding RNA functions as a competitive endogenous RNA to modulate TaNAC018 by acting as a decoy for tae-miR6206
Increasing evidence indicates a strong correlation between the deposition of cuticular waxes and drought tolerance. However, the precise regulatory...
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Landscape of internal N7-methylguanosine of long non-coding RNA modifications in resistant acute myeloid leukemia
BackgroundGrowing evidence indicates that RNA methylation plays a fundamental role in epigenetic regulation, which is associated with the...
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Transcriptome and methylome sequencing reveals altered long non-coding RNA genes expression and their aberrant DNA methylation in equine sarcoids
Recent publications confirmed that long non-coding RNAs (lncRNAs) perform an essential function in gene-specific transcription regulation....
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The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion
BackgroundLong non-coding RNAs (lncRNAs) regulate cellular processes by interacting with RNAs or proteins. Transforming growth factor β (TGFβ)...
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Role of long non-coding RNA in plant responses to abiotic stresses
As a kind of over 200 nt RNA, long non-coding RNA (lncRNA) has no protein-coding ability. It exists in a large number of organisms and has multiple...
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Interrelated grid of non-coding RNA: An important aspect in Rheumatoid Arthritis pathogenesis
Inflammation and autoimmunity are the root cause of rheumatoid arthritis, a destructive disease of joints. Multiple biomolecules are involved in the...
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Long non-coding RNA in coronary artery disease: the role of PDXDC1-AS1 and SFI1-AS1
This study investigates the interaction between long non-coding RNAs (lncRNAs) and metabolic risk factors that contribute to coronary artery disease...
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Genome-wide in silico analysis of long intergenic non-coding RNAs from rice peduncles at the heading stage
Long intergenic non-coding RNAs (lincRNAs) belong to the category of long non-coding RNAs (lncRNAs), originated from intergenic regions, which do not...
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Long Non-coding RNAs, Lnc(ing) RNA Metabolism to Cancer Biology
The eukaryotic genome is represented by a vast proportion of non-coding regions, which in recent years have been attributed to have important...
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Construction of a m5C-related long non-coding RNA signature for the prognosis of hepatocellular carcinoma
RNA modification serves as a kind of posttranscriptional modification. Besides N6-methyladenosine (m6A), 5-methylcytosine(m5C) is also an important...
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Long non-coding RNAs: definitions, functions, challenges and recommendations
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes of complex organisms. The term ‘lncRNAs’ encompasses RNA...
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Long Non-coding RNAs and CRISPR-Cas Edition in Tumorigenesis
Long non-coding RNAs (lncRNAs) are one of the most abundant and heterogeneous transcripts with key roles in chromatin remodeling and gene regulation...
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The landscape of the long non-coding RNAs in develo** mouse retinas
BackgroundThe long non-coding RNAs (lncRNAs) are critical regulators of diverse biological processes. Nevertheless, a global view of its expression...
