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Emergence and maintenance of stable coexistence during a long-term multicellular evolution experiment
The evolution of multicellular life spurred evolutionary radiations, fundamentally changing many of Earth’s ecosystems. Yet little is known about how...
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Within-host genomic evolution of methicillin-resistant Staphylococcus aureus in long-term carriers
AbstractAssessing the genomic evolution of Staphylococcus aureus can help us understand how the bacteria adapt to its environment. In this study, we...
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Evolution of Red Soil Fertility and Response of Rice Yield Under Long-Term Fertilization
[ Purpose ] In order to evaluate the evolutionary trends of integrated fertility in red soil rice fields under different long-term fertilization...
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Revisiting the Design of the Long-Term Evolution Experiment with Escherichia coli
The long-term evolution experiment (LTEE) with Escherichia coli began in 1988 and it continues to this day, with its 12 populations having recently...
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High-density cortical µECoG arrays concurrently track spreading depolarizations and long-term evolution of stroke in awake rats
Spreading depolarizations (SDs) are widely recognized as a major contributor to the progression of tissue damage from ischemic stroke even if blood...
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Long-term evolution of quantitative traits in the Drosophila melanogaster species subgroup
Quantitative genetics aims at untangling the genetic and environmental effects on phenotypic variation. Trait heritability, which summarizes the...
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Long-Term Fluorescence Recovery After Photobleaching (FRAP)
Numerous models have been developed for the analysis of fluorescence recovery after photobleaching (FRAP), by which intracellular diffusion and... -
Long-Term Culturing of Placozoans (Trichoplax and Hoilungia)
The phylum Placozoa remains one of the least explored among early-branching metazoan lineages. For over 130 years, this phylum had been represented... -
Long-term expansion of cereal crops promotes regional population increase of polyphagous Helicoverpa armigera
Changes in land use is an important driver of insect pest population dynamics, but the long-term effects of land use may be contingent on changes in...
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Differential tempol effects in prostatic cancer: angiogenesis and short- and long-term treatments
Prostate cancer (PCa) is the second cause of cancer death among men worldwide. Several processes are involved in the development and progression of...
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Short-term evolution pattern in salt marsh landscapes: the importance of physical constraints
ContextSalt marsh landscapes at the land-sea interfaces exhibit contrasting spatiotemporal dynamics, resulting from varying physical constraints that...
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Best Practices in Microbial Experimental Evolution: Using Reporters and Long-Read Sequencing to Identify Copy Number Variation in Experimental Evolution
Copy number variants (CNVs), comprising gene amplifications and deletions, are a pervasive class of heritable variation. CNVs play a key role in...
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Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis
BackgroundMultiple sclerosis (MS) remains a highly unpredictable disease. Many hope that fluid biomarkers may contribute to better stratification of...
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Long-term Fertilizer Application Induces Changes in Carbon Storage and Distribution, and the Consequent Color of Black soil
This study investigated the impact of different fertilizer treatments on soil color and humic substances (HSs) in a maize crop** system over a...
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Long-term adjustment of phytoplankton structure to environmental traits at timescales during lifetime development and over generations
Long-term ecological research of deep Lake Mondsee covers over more than six decades of phytoplankton observation. According to our study,...
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Evolutionary honing in and mutational replacement: how long-term directed mutational responses to specific environmental pressures are possible
Recent results have shown that the human malaria-resistant hemoglobin S mutation originates de novo more frequently in the gene and in the population...
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Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms
Prolactin (PRL) is elevated in B-cell-mediated lymphoproliferative diseases and promotes B-cell survival. Whether PRL or PRL receptors drive the...
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Higher surface folding of the human premotor cortex is associated with better long-term learning capability
The capacity to learn enabled the human species to adapt to various challenging environmental conditions and pass important achievements on to the...
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The evolution of short- and long-range weapons for bacterial competition
Bacteria possess a diverse range of mechanisms for inhibiting competitors, including bacteriocins, tailocins, type VI secretion systems and...