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Assay of Monoacylglycerol Lipase Activity
Monoacylglycerol lipase (MGL/MAGL/MGLL) is a serine hydrolase involved in the biological deactivation of the endocannabinoid... -
Acylated Flavonoids from Cucumis sativus Inhibit the Activity of Human Pancreatic Lipase
Lipid metabolism disorders are a large group of diseases for the treatment of which various strategies are used, including the use of pancreatic...
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Macromolecular Interactions of Lipoprotein Lipase (LPL)
Lipoprotein lipase (LPL) is a critical enzyme in humans that provides fuel to peripheral tissues. LPL hydrolyzes triglycerides from the cores of... -
Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity
As an important hydrolytic enzyme that yields 2-AG and free fatty acids, diacylglycerol lipase alpha (DAGLA) is involved in exacerbating malignant...
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Purification and biochemical characterization of extracellular thermostable lipase from Bacillus sp. strain L2
In the current study, an extracellular thermostable lipase from Bacillus sp. strain L2 was produced and purified through two-steps purifications,...
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Activity and stability of lipase from Candida Antarctica after treatment in pressurized fluids
Lipase B from Candida antarctica (CalB) is one of the biocatalysts most used in organic synthesis due to its ability to act in several medium, wide...
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Construction of Pseudomonas aeruginosa SDK-6 with synthetic lipase gene cassette and optimization of different parameters using response surface methodology for over-expression of recombinant lipase
Lipases are industrially important enzymes having vast applications in various fields. Cloning and expression of lipase enzyme-encoding genes in...
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Utilization of Fusarium Solani lipase for enrichment of polyunsaturated Omega-3 fatty acids
Omega-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), offer numerous health benefits. Enriching these fatty acids...
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Extracellular lipase production by Yarrowia lipolytica under magnetic fields
This study aimed at estimating cultivation conditions to enable Yarrowia lipolytica NNRL Y-1095 to produce extracellular lipase and at evaluating the...
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Alkaliphilic and thermostable lipase production by leaf litter fungus Leptosphaerulina trifolii A SMR-2011
Fungi that inhabit fire-prone forests have to be adapted to harsh conditions and fungi affiliated to Ascomycota recovered from foliar litter samples...
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Sequencing analysis and efficient biodiesel production by lipase from Pseudomonas aeruginosa
BackgroundRecently, lipase processing for biodiesel production has shown a global increase as it is considered a potential alternative clean-fuel...
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Synthesis of Some Benzimidazole-Thiophene Hybrids as Potential Urease and Lipase Inhibitors
AbstractIn this study, some benzimidazole-thiophene hybrid compounds containing isatin and salicyl moieties were synthesized and investigated for...
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Optimization of lipase production by response surface methodology from Serratia marcescens VT 1 isolated from oil contaminated soil
The current manuscript focuses on the isolation of a potent lipase-producing mesophilic bacteria and explores the optimization of culture parameters...
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Intracellular-to-extracellular localization switch of acidic lipase in Enterobacter cloacae through multi-objective medium optimization: aqueous two-phase purification and activity kinetics
As physiological impairments that require replacement therapy continue to increase, so also does the need for improved production of acidic lipase...
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Screening, identification, and characterization of lipase-producing halotolerant Bacillus altitudinis Ant19 from Antarctic soil
Potent lipase-producing and halotolerant Bacillus altitudinis Ant19 strain was screened and isolated from Antarctic soil. The isolate showed...
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Production, purification, and characterization of cold-active lipase from the psychrotroph Pseudomonas sp. A6
Cold-active lipases are presently employed extensively in the detergent, chemical intermediate, fine chemical, food, and pharmaceutical industries....
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Umbelopsis (Mucoromycota) from Patagonia, Argentina: identification, phylogenetic analysis, and expression profiling of lipase activity and lipid accumulation in selected isolates
Umbelopsis Amos & H.L. Barnett ( Umbelopsidales , Mucoromycota ) is a fungal genus reported as a producer of lipases and lipids. In the Southern Cone of...
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A lipase from Lacticaseibacillus rhamnosus IDCC 3201 with thermostability and pH resistance for use as a detergent additive
AbstractLipases are important biocatalysts and ubiquitous in plants, animals, and microorganisms. The high growth rates of microorganisms with low...
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Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
Triple-negative breast cancer (TNBC) has a poor clinical outcome, due to a lack of actionable therapeutic targets. Herein we define lysosomal acid...
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Potential of Antarctic lipase from Acinetobacter johnsonii Ant12 for treatment of lipid-rich wastewater: screening, production, properties and applications
The present study aimed to screen and optimize lipase production by the Antarctic strain Acinetobacter johnsonii Ant12 for lipid-rich wastewater...