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Current advances in the biotechnological synthesis of betulinic acid: new findings and practical applications
Betulinic acid (BA), a penta-cyclic triterpenoid found as a ubiquitous secondary metabolite throughout the plant kingdom, has aroused tremendous...
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Accelerating the menaquinone-7 production in Bacillus amyloliquefaciens by optimization of the biosynthetic pathway and medium components
Menaquinone-7 (MK-7) has an important role in preventing diseases such as cardiovascular disease and osteoporosis. In this study, a combination...
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Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli
The biotechnological production of isoprene and isopentenol has recently been studied. Isoprene, which is currently made mainly from petroleum, is an...
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Recent advances in lycopene and germacrene a biosynthesis and their role as antineoplastic drugs
Sesquiterpenes and tetraterpenes are classes of plant-derived natural products with antineoplastic effects. While plant extraction of the...
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Defensive Specialized Metabolites from the Latex of Euphorbia jolkinii
Plant latex is sequestered in laticiferous structures and exuded immediately from damaged plant tissues. The primary function of plant latex is...
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Citrus medica var. Sarcodactylus (Siebold ex Hoola van Nooten) Swingle: an insight into its botany, traditional uses, phytochemistry, and pharmacological properties
Citrus medica var. sarcodactylus (Siebold ex Hoola van Nooten) Swingle is not only a delicious fruit with rich nutrients, but also a traditional...
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Strategies for the efficient biosynthesis of β-carotene through microbial fermentation
β-Carotene is an orange fat-soluble compound, which has been widely used in fields such as food, medicine and cosmetics owing to its anticancer,...
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GlPS1 overexpression accumulates coumarin secondary metabolites in transgenic Arabidopsis
The dried root of Glehnia littoralis is a traditional Chinese herbal medicine mainly used to treat lung diseases and plays an important role in...
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Synthetic biology for sustainable food ingredients production: recent trends
Problems with food security result from increased population, global warming, and decrease in cultivable land. With the advancements in synthetic...
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Metabolic Engineering: New Approaches in Pharmaceutical Production
Natural products, natural products-derived, and natural products-inspired compounds represent a major sector of drugs and drug leads. Nature has the...
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Microbial Production of Lycopene
Lycopene is a terpenoid composed of 40 carbons characterized by its linear structure compared to other carotenoids. It has been attributed to...
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Recent Progress in CRISPR-Based Technology Applications for Biofuels Production
Biofuels due to their high energy production capacity, cost-effectiveness, and high energy density have been shown to be good candidates as suitable...
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Genome Editing Tool CRISPR-Cas: Legal and Ethical Considerations for Life Science
CRISPR-Cas has wide applications in preclinical and clinical research, biomedicine, and agriculture. The use of genome editing tool CRISPR-Cas, which...
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Microbial Production of Limonene
Limonene is a valuable natural product with diverse applications in food, pharmaceutical, paints and coatings, chemicals, etc. Commercial production...
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Recent Advances in Metabolic Engineering and Synthetic Biology for Microbial Production of Isoprenoid-Based Biofuels: An Overview
Isoprenoids have been reported to be the diverse and most abundant natural products with various applications. Microbial approaches have recently...
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Microbial Production of Pharmaceutically Important Plant Natural Products
Plant natural products have assumed pivotal roles within the food, cosmetic, and pharmaceutical sectors, serving as invaluable sources of fragrances,...
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Fine-tuning gene expression of regulator AdmX for improved biosynthesis of andrimid in Erwinia persicina BST187
AbstractAndrimid is a potent antibiotic that inhibits acetyl-CoA carboxylase. However, its low biological yield and complex chemical synthesis have...
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Recent advances in construction and regulation of yeast cell factories
The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast...
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Machine learning: an advancement in biochemical engineering
One of the most remarkable techniques recently introduced into the field of bioprocess engineering is machine learning. Bioprocess engineering has...
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Biotechnological production of lycopene by microorganisms
AbstractLycopene is a dark red carotenoid belonging to C40 terpenoids and is widely found in a variety of plants, especially ripe red fruits and...
