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Dose-dependent effects of acetaminophen and ibuprofen on mitochondrial respiration of human platelets
Acetaminophen and ibuprofen are widely used over-the-counter medications to reduce fever, pain, and inflammation. Although both drugs are safe in...
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Response of hepatic biochemical parameters and neurotoxicity to carbamazepine and ibuprofen in Oreochromis mossambicus
Globally, the prevalence and pollution of pharmaceutical drugs in aquatic environments have been steadily increasing. This study sought to evaluate...
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Intermediate Levels of Predation and Nutrient Enrichment Enhance the Activity of Ibuprofen-Degrading Bacteria
Water is the most indispensable natural resource; yet, organic pollution of freshwater sources is widespread. In recent years, there has been...
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Biotransformation of Ibuprofen using Providencia rettgeri 2AJS and Streptomyces tendae AJ1
AbstractThe present research paper is devoted to bio-degradation of ibuprofen, one of the non-steroidal anti-inflammatory medicines that is most...
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Conjugates of ibuprofen inhibit CHIKV infection and inflammation
Chikungunya virus infection has become a global health concern because of its high rates of morbidity and mortality in patients with preexisting...
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Does ibuprofen affect the expression of alginate genes in pathogenic Pseudomonas aeruginosa strains?
Conversion to mucoid form is a crucial step in the pathogenesis of P. aeruginosa in burns and cystic fibrosis (CF) patients. Alginate is considered...
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Evaluation of the effect of ibuprofen in combination with ciprofloxacin on the virulence-associated traits, and efflux pump genes of Pseudomonas aeruginosa
Biofilm formation and antibiotic efflux are two determinant factors in the development of drug resistance phenotype by Pseudomonas aeruginosa. ...
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Ibuprofen involves with the reduced expression of pelD and pelF in pathogenic Pseudomonas aeruginosa strains
Biofilm formation is an important factor in disease development by Pseudomonas aeruginosa . Similar to many bacterial species, biofilm formation in P....
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Biotransformation activities of fungal strain apiotrichum sp. IB-1 to ibuprofen and naproxen
Ibuprofen (IBU) and naproxen (NPX), as widely prescribed non-steroidal anti-inflammatory drugs (NSAIDs), are largely produced and consumed globally,...
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Interactive multiple binding of oleic acid, warfarin and ibuprofen with human serum albumin revealed by thermal and fluorescence studies
Human serum albumin binds a wide variety of drugs with different structure and affinity to two main binding sites, drug site 1 (DS1) and drug site 2...
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A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ
Berberine (BBR) exerts specific therapeutic effects on various diseases such as diabetes, obesity, and other inflammation-associated diseases....
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Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
AbstractSome novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized...
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Evaluation of ibuprofen contamination in local urban rivers and its effects on immune parameters of juvenile grass carp
Ibuprofen as a non-steroidal anti-inflammatory drug can be detected in the aquatic environments all over the world. This study evaluated the effects...
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Microbial Degradation of Nonsteroidal Anti-inflammatory Drug Ibuprofen
Pharmaceutical consumption is gradually increasing because of improved health care systems in India and worldwide. The occurrence of pharmaceuticals...
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Characteristics and growth kinetics of biomass of Citrobacter freundii strains PYI-2 and Citrobacter portucalensis strain YPI-2 during the biodegradation of Ibuprofen
Ibuprofen (IBU) is the third most commonly used analgesic drug in the world. It enters the water system as a result of human excretion-based...
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Anti-Sporothrix activity of ibuprofen combined with antifungal
The in vitro activity of ibuprofen, a nonsteroidal anti-inflammatory drug, was evaluated against Sporothrix brasiliensis and S. schenckii , either...
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Effects of simultaneous intake of chamomile and ibuprofen on delayed-onset muscle soreness markers and some liver enzymes following eccentric exercise
Delayed-onset muscle soreness (DOMS) occurs after intense eccentric contractions or after performing unaccustomed exercise. Chamomile and ibuprofen...
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Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics
Antimicrobial resistance can arise in the natural environment via prolonged exposure to the effluent released by manufacturing facilities. In...
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Analyzing microbial communities and their biodegradation of multiple pharmaceuticals in membrane bioreactors
AbstractPharmaceuticals are of concern to our planet and health as they can accumulate in the environment. The impact of these biologically active...
