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The Effect of Peroxynitrite and tert-Butyl Hydroperoxide on Thiol Ligands of Dinitrosyl Iron Complexes
Low-molecular-weight dinitrosyl iron complexes (DNICs) with thiol-containing ligands are a physiological form for deposit and transport of nitric...
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Analysis of Anti-Inflammatory Properties of Plant Oxylipins Produced in the Hydroperoxide Lyase Branch
AbstractShort-chain and medium-chain aldehydes and their derivatives, yielded by the enzymes hydroperoxide lyases from fatty acids, are present in...
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The beneficial effects of the tobacco hydroperoxide lyase pathway in whitefly host adaptation
Plants respond to herbivore attack by emitting complex mixtures of volatile compounds to repel herbivores or attract predators and parasitoids. In...
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Biosynthesis of natural aroma compounds using recombinant whole-cell tomato hydroperoxide lyase biocatalyst
Green leaf volatiles impart characteristic aroma and flavour to a variety of natural foods due to their inherent grassy note contributed by...
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Cholesterol Hydroperoxide Co-trafficking in Testosterone-generating Leydig Cells: GPx4 Inhibition of Cytotoxic and Anti-steroidogenic Effects
Trafficking of intracellular cholesterol (Ch) to and into mitochondria of steroidogenic cells is required for steroid hormone biosynthesis. This...
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Characterization of oxidative stress-induced cgahp, a gene coding for alkyl hydroperoxide reductase, from industrial importance Corynebacterium glutamicum
Alkyl hydroperoxide reductase (Ahp), comprised of four different subunits AhpC, AhpD, AhpE, and AhpF, is a thiol-based antioxidative enzyme with the...
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Hydroperoxide-Reducing Enzymes in the Regulation of Free-Radical Processes
AbstractThe review presents current concepts of the molecular mechanisms of oxidative stress development and describes main stages of the...
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Peroxidase Activity of Leghemoglobin of Bean (Vicia faba L.) Nodules in Relation to Tert-Butyl Hydroperoxide
AbstractLike many other hemoglobins, leghemoglobin (Lb), the hemoglobin of legume nodules, demonstrates peroxidase activity and can oxidize various...
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Maternal zinc alleviates tert-butyl hydroperoxide-induced mitochondrial oxidative stress on embryonic development involving the activation of Nrf2/PGC-1α pathway
BackgroundMitochondrial dysfunction induced by excessive mitochondrial reactive oxygen species (ROS) damages embryonic development and leads to...
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Inactivation of Ras1 in Fission Yeast Aggravates the Oxidative Stress Response Induced by Tert Butyl Hydroperoxide (tBHP)
AbstractRas proteins are small GTPases and function as molecular switches to regulate cellular homeostasis. Ras-dependent signalling pathways...
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Preparation, validation and use of a vasoactive tryptophan-derived hydroperoxide and relevant control compounds
The l -tryptophan–derived tricyclic hydroperoxide cis -WOOH was recently identified as a novel and biologically important factor for regulating...
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A small molecule interacts with pMAC-derived hydroperoxide reductase and enhances the activity of aminoglycosides
The threat of antimicrobial resistance calls for more efforts in basic science, drug discovery, and clinical development, particularly gram-negative...
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Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes
Molecular hydrogen (H 2 ) is recognized as a gaseous antioxidant, and it is expected to ameliorate various disorders related to oxidative stress and...
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Molecular Cloning and the Expression Pattern of a Phospholipid Hydroperoxide Glutathione Peroxidase in Kalidium foliatum under NaCl Treatment
AbstractThe halophyte Kalidium foliatum (Pall.) Moq. exhibits strong tolerance to salinity. Salt stress leads to reactive oxygen species (ROS)...
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A comparative proteomic analysis of Candida species in response to the oxidizing agent cumene hydroperoxide
Candida genus comprises several species that can be found in the oral cavity and the gastrointestinal and genitourinary tracts of healthy...
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Activation of HSP70 impedes tert-butyl hydroperoxide (t-BHP)-induced apoptosis and senescence of human nucleus pulposus stem cells via inhibiting the JNK/c-Jun pathway
The endogenous repair failure of degenerated intervertebral disk (IVD) is highly related to the exhaustion of nucleus pulposus stem cells (NPSCs)....
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Versatile ferrous oxidation–xylenol orange assay for high-throughput screening of lipoxygenase activity
AbstractLipoxygenases (LOXs) catalyze dioxygenation of polyunsaturated fatty acids (PUFAs) into fatty acid hydroperoxides (FAHPs), which can be...
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Functional properties and the oligomeric state of alkyl hydroperoxide reductase subunit F (AhpF) in Pseudomonas aeruginosa
Alkyl hydroperoxide reductase subunit F (AhpF) is a well-known flavoprotein that transfers electrons from pyridine nucleotides to the peroxidase...
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Synthesis of 12-aminododecenoic acid by coupling transaminase to oxylipin pathway enzymes
AbstractBiobased polymers derived from plant oils are sustainable alternatives to petro based polymers. In recent years, multienzyme cascades have...
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Molecular detection and whole genome sequencing of Pectobacterium and Dickeya, the casual agents of soft rot disease in lettuce
Lettuce plants displaying vein discoloration, wilting, soft rot at the base and emitting foul odour were observed at several major lettuce growing...