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Editing the Genome of the Golden Hamster (Mesocricetus auratus)
The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent belonging to the Cricetidae family. Golden hamsters have several unique...
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Ultrasonographic and macroscopic study of pregnancy in golden hamster
BackgroundHamster is widely used as an experimental model in the study of reproductive system. However, pregnancy diagnosis and aging always have...
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Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters
Many animals have a conserved adaptive genome defence system known as the Piwi-interacting RNA (piRNA) pathway, which is essential for germ cell...
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Optimization and comparative analysis of LAMP and PCR techniques for the detection of leptospiral DNA in Golden Syrian hamsters
Leptospirosis is a zoonotic disease with significant public health and economic impact worldwide. Rapid and accurate diagnosis is essential for...
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SARS-CoV-2 infection induces persistent adipose tissue damage in aged golden Syrian hamsters
Coronavirus disease 2019 (COVID-19, caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)) is primarily a respiratory illness....
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Genetically Engineered Hamster Models of Dyslipidemia and Atherosclerosis
Animal models of human diseases play an extremely important role in biomedical research. Among them, mice are widely used animal models for...
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The piRNA pathway is essential for generating functional oocytes in golden hamsters
Piwi-interacting RNAs (piRNAs) are predominantly expressed in germ cells and function in gametogenesis in various species. However, Piwi -deficient...
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The Laboratory Hamster
Hamsters are one of the commonly used animal species in research related to virology and infectious agents. Hamsters are similar to human beings in...
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Formation of spermatogonia and fertile oocytes in golden hamsters requires piRNAs
PIWI-interacting RNAs (piRNAs) support the germline by suppressing retrotransposons. Studies of the pathway in mice have strongly shaped the view...
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Mucin-producing hamster cholangiocarcinoma cell line, Ham-2, possesses the aggressive cancer phenotypes with liver and lung metastases
Cholangiocarcinoma (CCA) is an aggressive bile duct cancer. Opisthorchis viverrini ( O. viverrini ) infection is a significant cause of CCA in the...
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Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
Nanobodies offer several potential advantages over mAbs for the control of SARS-CoV-2. Their ability to access cryptic epitopes conserved across...
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Housing conditions modify seasonal changes in basal metabolism and body mass of the Siberian hamster, Phodopus sungorus
Proper housing conditions are important aspects of animal welfare. Animals housed in enriched environments show less stereotypic behaviours than...
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Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol
Mammalian hibernators endure severe and prolonged hypothermia that is lethal to non-hibernators, including humans and mice. The mechanisms...
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Morphology of the pattern of branching of the aortic arch (Arcus aortae) in Syrian hamsters (Mesocricetus auratus)
The branching patterns of the aortic arches of 28 adult male and female Syrian hamsters (SH) were thoroughly examined under a stereomicroscope for...
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Standardization of chronic uterine infection of hamsters by Leptospira santarosai serovar Guaricura, from serogroup Sejroe
Leptospirosis is an important zoonosis that in cattle is characterized as a reproductive disease. It is well reported that the main agent of bovine...
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Expression analysis suggests that DNMT3L is required for oocyte de novo DNA methylation only in Muridae and Cricetidae rodents
BackgroundDuring early mammalian development, DNA methylation undergoes two waves of reprogramming, enabling transitions between somatic cells,...
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Modifying effects of nerolidol on cell surface glycoconjugates and suppressed inflammation during DMBA-induced oral carcinogenesis: An in vivo and in silico
Oral squamous cell carcinomas (OSCC) were created in the buccal pouches of golden Syrian hamsters by painting them three times a week with 0.5% DMBA...
