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Genes and Regulatory Mechanisms for Ginsenoside Biosynthesis
Panax ginseng is a medicinal plant belonging to the Araliaceae family. Ginseng is known as the king of oriental medicine, which has been practiced...
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Effects of growth years on ginsenoside biosynthesis of wild ginseng and cultivated ginseng
BackgroundGinsenoside, as the main active substance in ginseng, has the function of treating various diseases. However, the ginsenosides content of...
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Production of ginsenoside compound K by microbial cell factory using synthetic biology-based strategy: a review
Ginsenoside compound K (CK) is a major intestinal bacterial metabolite of the protopanaxadiol-type ginsenoside family that can be absorbed in the...
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Identification of two key UDP-glycosyltransferases responsible for the ocotillol-type ginsenoside majonside-R2 biosynthesis in Panax vietnamensis var. fuscidiscus
Main conclusionTwo UDP-glycosyltransferases from Panax vienamensis var. fuscidiscus involved in ocotillol-type ginsenoside MR2 (majonside-R2)...
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Sucrose Induced HMGR to Promote Ginsenoside Biosynthesis in the Growth of Wild Cultivated Ginseng (Panax ginseng)
Wild cultivated ginseng is considered to be of higher quality than field-cultivated ginseng. Many active constituents of wild cultivated ginseng,...
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Effective prediction of biosynthetic pathway genes involved in bioactive polyphyllins in Paris polyphylla
The genes in polyphyllins pathway mixed with other steroid biosynthetic genes form an extremely complex biosynthetic network in Paris polyphylla with...
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Combining Metabolomics and Metagenomics to Analyze the Biosynthetic Potential of Culturable Endophytic Fungi Isolated from Salvia miltiorrhiza
AbstractPlant endophytic fungi are reservoirs of novel bioactive natural products, which may be used directly or indirectly to treat numerous...
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Differential expression of ginsenoside biosynthesis-related genes at an early developmental stage of Panax vietnamensis
Panax vietnamensis Ha et Grushv., an important medicinal plant in Vietnam, consists of several valuable ginsenosides. Compared to other Panax ...
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Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae
Rg2 and Re are both rhamnose-containing ginsenosides isolated exclusively from Panax plants, which exhibit broad spectrum of pharmacological...
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Metabolic Dynamics and Ginsenoside Biosynthesis
Panax ginseng, a medicinally important perennial herb, has been widely used as the medicinal plant in South East Asian countries such as Korea,...
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Transcriptional responses for biosynthesis of ginsenoside in arbuscular mycorrhizal fungi-treated Panax quinquefolius L. seedlings using RNA-seq
Panax quinquefolius L. has been considered as an important traditional Chinese medicine with a history of more than 300 years in China. Ginsenoside...
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Ginsenoside Biosynthesis in Panax Ginseng with Red-Skin Disease Is Inhibited by Soil Characteristics
Red-skin disease (RSD) is a common soil-borne disease encountered during ginseng cultivation. We found that RSD was closely related to soil...
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Advances in the biosynthesis and metabolic engineering of rare ginsenosides
AbstractRare ginsenosides are the deglycosylated secondary metabolic derivatives of major ginsenosides, and they are more readily absorbed into the...
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Effects of arbuscular mycorrhizal fungi on photosynthesis and biosynthesis of ginsenoside in Panax quinquefolius L.
Panax quinquefolius L., a medicinal plant of Araliaceae family, is used in traditional Chinese medicine. Arbuscular mycorrhizal fungi (AMF) has been...
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Recent Trends in Elicitation and Secondary Metabolic Pathway Analysis in Medicinal Plants: An Integrated Transcriptomics and Proteomics Approach
The medicinal plants are nature’s treasured gift, which have immeasurable influence on human life and are the vital source of numerous structurally...
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Changes in the physiological characteristics of Panax ginseng embryogenic calli and molecular mechanism of ginsenoside biosynthesis under cold stress
Main conclusionShort-term cold stress can induce the increased expression of key enzyme-encoding genes involved in secondary metabolite synthesis,...
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Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major
Main conclusionTwo UDP-glycosyltransferases from Panax japonicus var. major were identified, and the biosynthetic pathways of three oleanane-type...
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Screening and identification of effective components from modified Taohong Siwu decoction for protecting H9c2 cells from damage
We found that modified Taohong Siwu decoction (MTHSWD) had cardioprotective effects after myocardial ischemia–reperfusion injury. This study was to...
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Elicitation with sodium nitroprusside and Trichoderma improves vincristine and vinblastine yield in Catharanthus roseus cell suspension culture by modulating terpenoid indole alkaloid pathway genes
Plant secondary metabolites production is increased in response to both biotic and abiotic elicitors. This study investigates the impact of sodium...
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Synthetic Biology of Ginsenosides
Ginsenosides, a group of triterpenoid saponins, are the signature compounds from plants in the genus Panax. Ginsenosides display a variety of...