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Skeletal Muscle Receptors
This amazing chapter takes a deep dive into the realm of skeletal muscle receptors, particularly emphasizing the Vitamin D receptor (VDR) and the...
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Basic Structure of Skeletal Muscle
Building on the foundational understanding established in the first chapter, Chap. 2 explores the burgeoning...
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Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure
In striated muscle, the sarcomeric protein myosin-binding protein-C (MyBP-C) is bound to the myosin thick filament and is predicted to stabilize...
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Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging
Skeletal muscle aging is characterized by the loss of muscle mass, strength and function, mainly attributed to the atrophy of glycolytic fibers....
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Human skeletal muscle aging atlas
Skeletal muscle aging is a key contributor to age-related frailty and sarcopenia with substantial implications for global health. Here we profiled...
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Skeletal Muscle Energy Metabolism & Contraction
Skeletal muscle contraction and energy metabolism are closely intertwined processes essential for maintaining physiological functions and supporting...
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Adipocyte Rnf20 ablation increases the fast-twitch fibers of skeletal muscle via lysophosphatidylcholine 16:0
Both adipose tissue and skeletal muscle are highly dynamic tissues and interact at the metabolic and hormonal levels in response to internal and...
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The Effects of Exercise on Skeletal Muscle
This chapter investigates the profound effects of exercise on skeletal muscle. In its many forms, exercise plays an indisputable role in influencing...
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Epigenetic control of skeletal muscle atrophy
Skeletal muscular atrophy is a complex disease involving a large number of gene expression regulatory networks and various biological processes....
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Skeletal Muscle Regeneration in Zebrafish
Muscle regeneration models have revealed mechanisms of inflammation, wound clearance, and stem cell–directed repair of damage, thereby informing...
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Exercise metabolism and adaptation in skeletal muscle
Viewing metabolism through the lens of exercise biology has proven an accessible and practical strategy to gain new insights into local and systemic...
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Lunar gravity prevents skeletal muscle atrophy but not myofiber type shift in mice
Skeletal muscle is sensitive to gravitational alterations. We recently developed a multiple artificial-gravity research system (MARS), which can...
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Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis
Skeletal muscle is dynamically controlled by the balance of protein synthesis and degradation. Here we discover an unexpected function for the...
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Transcriptomic and metabolomic dissection of skeletal muscle of crossbred Chongming white goats with different meat production performance
BackgroundThe transcriptome and metabolome dissection of the skeletal muscle of high- and low- growing individuals from a crossbred population of the...
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Tropomyosin 3 (TPM3) function in skeletal muscle and in myopathy
The tropomyosin genes ( TPM1-4 ) contribute to the functional diversity of skeletal muscle fibers. Since its discovery in 1988, the TPM3 gene has been...
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MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury
Skeletal muscle is a highly specialized tissue composed of myofibres that performs crucial functions in movement and metabolism. In response to...
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Fast and slow skeletal myosin binding protein-C and aging
Aging is associated with skeletal muscle strength decline and cardiac diastolic dysfunction. The structural arrangements of the sarcomeric proteins,...
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Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues
While the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and...
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Spaceflight on the ISS changed the skeletal muscle proteome of two astronauts
Skeletal muscle undergoes atrophy and loss of force during long space missions, when astronauts are persistently exposed to altered gravity and...
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Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice
Sarcopenia, a progressive and prevalent neuromuscular disorder, is characterized by age-related muscle wasting and weakening. Despite its widespread...
