Search
Search Results
-
M1-derived extracellular vesicles polarize recipient macrophages into M2-like macrophages and alter skeletal muscle homeostasis in a hyper-glucose environment
BackgroundMacrophages release not only cytokines but also extracellular vesicles (EVs). which are small membrane-derived nanovesicles with virus-like...
-
Extracellular vesicles derived from “serum and glucose” deprived HUCMSCs promoted skin wound healing through enhanced angiogenesis
Extracellular vesicles (EVs) produced from MSCs were currently considered as a novel therapeutic agent for skin tissue regeneration and repair....
-
Short note: extracellular export and consumption of glucose in Antarctic sea ice
Extracellular carbohydrate production is widespread in sea ice microbial communities, being produced by both algae and bacteria. Under stressful...
-
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer
Nutrient-limiting conditions are common during cancer development. The coordination of cellular glucose levels and cell survival is a fundamental...
-
The ovine conceptus utilizes extracellular serine, glucose, and fructose to generate formate via the one carbon metabolism pathway
Highly proliferative cells rely on one carbon (1C) metabolism for production of formate required for synthesis of purines and thymidine for nucleic...
-
Anti-Inflammatory Properties of Metformin During Cultivation of Primary Rat Astrocytes in a Medium with High Glucose Concentration
AbstractInvestigation of the relationship between inflammation and energy metabolism is important for understanding biology of chronic...
-
Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth
Epidemiological studies demonstrate an association between breast cancer (BC) and systemic dysregulation of glucose metabolism. However, how BC...
-
TLR3-mediated Astrocyte Responses in High and Normal Glucose Adaptation Differently Regulated by Metformin
Toll-like receptors 3 (TLR3) are innate immune receptors expressed on a wide range of cell types, including glial cells. Inflammatory responses...
-
The glucose transporter 2 regulates CD8+ T cell function via environment sensing
T cell activation is associated with a profound and rapid metabolic response to meet increased energy demands for cell division, differentiation and...
-
Extracellular vesicles from the mycoparasitic fungus Trichoderma harzianum
Trichoderma harzianum is a filamentous fungus that can act as a mycoparasite, saprophyte, or a plant symbiotic. It is widely used as a biological...
-
Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter
Sodium–glucose cotransporter 2 (SGLT2) is imporant in glucose reabsorption. SGLT2 inhibitors suppress renal glucose reabsorption, therefore reducing...
-
Extracellular lipase production by Yarrowia lipolytica under magnetic fields
This study aimed at estimating cultivation conditions to enable Yarrowia lipolytica NNRL Y-1095 to produce extracellular lipase and at evaluating the...
-
Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization
The obesity epidemic continues to worsen worldwide, driving metabolic and chronic inflammatory diseases. Thiazolidinediones, such as rosiglitazone...
-
Liver-derived extracellular vesicles improve whole-body glycaemic control via inter-organ communication
Small extracellular vesicles (EVs) are signalling messengers that regulate inter-tissue communication through delivery of their molecular cargo....
-
Extracellular pH and high concentration of potassium regulate the primary necrosis in the yeast Saccharomyces cerevisiae
Extracellular pH and concentration of K + as well as their gradient across the plasma membrane have a significant impact on the physiology of the...
-
Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL
Metabolic crosstalk of the major nutrients glucose, amino acids and fatty acids (FAs) ensures systemic metabolic homeostasis. The coordination...
-
Extracellular Enzyme Activity and Stoichiometry Across Vegetated and Non-Vegetated Coastal Ecosystems
The conversion of organic matter by extracellular enzymes can reveal important insights into carbon and nutrient cycling. The activity and...
-
The effect of ionic redistributions on the microwave dielectric response of cytosol water upon glucose uptake
The sensitivity of cytosol water's microwave dielectric (MD) response to D-glucose uptake in Red Blood Cells (RBCs) allows the detailed study of...
-
Extracellular vesicles derived from Lactobacillus plantarum restore chemosensitivity through the PDK2-mediated glucose metabolic pathway in 5-FU-resistant colorectal cancer cells
Metabolic abnormalities are one of the main hallmarks of cancer and are associated with chemoresistance. Therefore, targeting the metabolic...
-
Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria
Glycogen serves as a metabolic sink in cyanobacteria. Glycogen deficiency causes the extracellular release of distinctive metabolites such as...
