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Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments
Ligaments are collagenous connective tissues that connect bones. Injury of knee ligaments, namely anterior cruciate ligament (ACL) and medial...
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GeneXpert Ultra in Urine Samples for Diagnosis of Extra-Pulmonary Tuberculosis
Extra-pulmonary tuberculosis (EPTB) continues to be difficult to diagnose. Novel biomarkers in biological specimens offer promise. Detection of Mycobac...
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Exposure of Arsenic Associated with Cellular Turnover and Apoptosis Profile in the Bone Marrow of Mice Including Stem/Progenitor Population
Arsenic toxicity is a current global concern due to its devastating toxic effects on human health. Over several millions of people are exposed to...
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PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway
Acute lung injury (ALI) is a common clinical syndrome, which often results in pulmonary edema and respiratory distress. It has been recently reported...
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Oxygen toxicity: cellular mechanisms in normobaric hyperoxia
In clinical settings, oxygen therapy is administered to preterm neonates and to adults with acute and chronic conditions such as COVID-19, pulmonary...
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Uterine lumen fluid is metabolically semi-autonomous
Uterine lumen fluid (ULF) is central to successful pregnancy establishment and maintenance, and impacts offspring wellbeing into adulthood. The...
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High throughput 3D gel-based neural organotypic model for cellular assays using fluorescence biosensors
Three-dimensional (3D) organotypic models that capture native-like physiological features of tissues are being pursued as clinically predictive...
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The effects of real and simulated microgravity on cellular mitochondrial function
Astronauts returning from space shuttle missions or the International Space Station have been diagnosed with various health problems such as bone...
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Transmembrane potential, an indicator in situ reporting cellular senescence and stress response in plant tissues
BackgroundPlant cells usually sustain a stable membrane potential due to influx and/or efflux of charged ions across plasma membrane. With the growth...
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Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels
Leucine-rich repeat-containing protein 8 (LRRC8) family members form volume-regulated anion channels activated by hypoosmotic cell swelling. LRRC8...
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Influence of the Supercritical Fluid Extraction (SFE) on Food Bioactives
This chapter provides a view of the effects of supercritical fluid extraction on food bioactives. First, a review of essential concepts on...
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Cellular Memory
The identity of cells in an organism is largely defined by their specific transcriptional profile. During cell division, these profiles need to be...
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Thirst: neuroendocrine regulation in mammals
Animals can sense their changing internal needs and then generate specific physiological and behavioural responses in order to restore homeostasis....
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QuickPIV: Efficient 3D particle image velocimetry software applied to quantifying cellular migration during embryogenesis
BackgroundThe technical development of imaging techniques in life sciences has enabled the three-dimensional recording of living samples at...
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Reconstruction of ovine axonal cytoarchitecture enables more accurate models of brain biomechanics
There is an increased need and focus to understand how local brain microstructure affects the transport of drug molecules directly administered to...
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Transcription Dynamics: Cellular Automaton Model of Polymerase Dynamics for Eukaryotes
This chapter introduces the cellular automata models for expressing RNA polymerase II dynamics in transcription. Cellular automata can represent...
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Evaluation of Cardiotonic Steroid Modulation of Cellular Cholesterol and Phospholipid
We have previously shown that 21-benzylidene digoxin (21-BD) increases the total cholesterol and phospholipid content on the membrane of HeLa cells....
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Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions
Exposure to microgravity and ionizing radiation during spaceflight missions causes excessive reactive oxygen species (ROS) production that...
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Ruta graveolens, Peganum harmala, and Citrullus colocynthis methanolic extracts have in vitro protoscolocidal effects and act against bacteria isolated from echinococcal hydatid cyst fluid
Echinococcosis is a common and endemic disease that affects both humans and animals. In this study, the in vitro activities of methanolic extracts of R...
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A case report of a rapid development of fetal anasarca in a canine pregnancy at term
A 5-year-old healthy pluriparous pregnant Flat-coated Retriever bitch was monitored by ultrasound on post-ovulation days 30 and 57: no deviation from...
