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Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments
Ligaments are collagenous connective tissues that connect bones. Injury of knee ligaments, namely anterior cruciate ligament (ACL) and medial...
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GeneXpert Ultra in Urine Samples for Diagnosis of Extra-Pulmonary Tuberculosis
Extra-pulmonary tuberculosis (EPTB) continues to be difficult to diagnose. Novel biomarkers in biological specimens offer promise. Detection of Mycobac...
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Extra-nuclear histones: origin, significance and perspectives
Histones are classically known to organize the eukaryotic DNA into chromatin. They are one of the key players in regulating transcriptionally...
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From freezing to functioning: cellular strategies of cold-adapted bacteria for surviving in extreme environments
The ability of cold-adapted bacteria to survive in extreme cold and diverse temperatures is due to their unique attributes like cell membrane...
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Exposure of Arsenic Associated with Cellular Turnover and Apoptosis Profile in the Bone Marrow of Mice Including Stem/Progenitor Population
Arsenic toxicity is a current global concern due to its devastating toxic effects on human health. Over several millions of people are exposed to...
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PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway
Acute lung injury (ALI) is a common clinical syndrome, which often results in pulmonary edema and respiratory distress. It has been recently reported...
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Oxygen toxicity: cellular mechanisms in normobaric hyperoxia
In clinical settings, oxygen therapy is administered to preterm neonates and to adults with acute and chronic conditions such as COVID-19, pulmonary...
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Evaluation of Molecular Interactions and Cellular Dynamics at the Maternal-Fetal Interface During Placental Morphogenesis
Molecular events at the maternal-fetal interface establish successful pregnancies. Identifying and characterizing the heterogeneous cell population...
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Uterine lumen fluid is metabolically semi-autonomous
Uterine lumen fluid (ULF) is central to successful pregnancy establishment and maintenance, and impacts offspring wellbeing into adulthood. The...
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High throughput 3D gel-based neural organotypic model for cellular assays using fluorescence biosensors
Three-dimensional (3D) organotypic models that capture native-like physiological features of tissues are being pursued as clinically predictive...
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Transmembrane potential, an indicator in situ reporting cellular senescence and stress response in plant tissues
BackgroundPlant cells usually sustain a stable membrane potential due to influx and/or efflux of charged ions across plasma membrane. With the growth...
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Mitochondrial disease, mitophagy, and cellular distress in methylmalonic acidemia
Mitochondria—the intracellular powerhouse in which nutrients are converted into energy in the form of ATP or heat—are highly dynamic,...
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Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development
Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose apical-basal polarity and loosen cell–cell junctions to...
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Oral-specific microenvironments regulate cell behavior and anticancer drug sensitivity of tongue squamous cell carcinoma
Squamous cell carcinoma (SCC) is the most major malignant tumor of the tongue. The tongue exists at the air–liquid interface and is covered with...
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Cloves (Syzygium aromaticum) fluid gel on healing of pododermatitis in rabbits
Wounds are damaging to quality life of confined animals, causing dysfunction in spinal, members injuries, and reduction in productive performance....
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Cellular Memory
The identity of cells in an organism is largely defined by their specific transcriptional profile. During cell division, these profiles need to be...
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Influence of the Supercritical Fluid Extraction (SFE) on Food Bioactives
This chapter provides a view of the effects of supercritical fluid extraction on food bioactives. First, a review of essential concepts on...
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The effects of real and simulated microgravity on cellular mitochondrial function
Astronauts returning from space shuttle missions or the International Space Station have been diagnosed with various health problems such as bone...
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Cellular Assay to Study β-Arrestin Recruitment by the Cannabinoid Receptors 1 and 2
Cannabinoid receptor 1 (CB1R) and cannabinoid receptor 2 (CB2R) are G protein-coupled receptors (GPCRs) that activate a variety of pathways upon...
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Impact of Helicobacter pylori infection on fluid duodenal microbial community structure and microbial metabolic pathways
BackgroundThe bioactivities of commensal duodenal microbiota greatly influence the biofunction of hosts. We investigated the role of Helicobacter...
