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Gut resistome linked to sexual preference and HIV infection
BackgroundPeople living with HIV (PLWH) are at increased risk of acquisition of multidrug resistant organisms due to higher rates of predisposing...
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Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures
Centenarians are an excellent model to study the relationship between the gut microbiome and longevity. To characterize the gut microbiome signatures...
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Uric acid, high density lipoprotein cholesterol levels and their ratio are related to microbial enterotypes and serum metabolites in females with a blood stasis constitution
BackgroundBlood stasis constitution in traditional Chinese medicine (TCM) is believed to render individuals more susceptible to metabolic diseases....
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Progression of swine fecal microbiota during early stages of life and its association with performance: a longitudinal study
BackgroundIt is vital to understand healthy gut microbiota composition throughout early life stages when environments are changing, and immunity is...
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Missing microbes in infants and children in the COVID-19 pandemic: a study of 1,126 participants in Bei**g, China
The COVID-19 pandemic has caused many fatalities worldwide and continues to affect the health of the recovered patients in the form of long-COVID. In...
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Multi-omics reveals that the host-microbiome metabolism crosstalk of differential rumen bacterial enterotypes can regulate the milk protein synthesis of dairy cows
BackgroundDairy cows’ lactation performance is the outcome of the crosstalk between ruminal microbial metabolism and host metabolism. However, it is...
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Temporal dynamics of the fecal microbiome in female pigs from early life through estrus, parturition, and weaning of the first litter of piglets
BackgroundAge-associated changes in the gastrointestinal microbiome of young pigs have been robustly described; however, the temporal dynamics of the...
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Deterministic transition of enterotypes shapes the infant gut microbiome at an early age
BackgroundThe succession of the gut microbiota during the first few years plays a vital role in human development. We elucidate the characteristics...
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The hallmarks of dietary intervention-resilient gut microbiome
Maintaining equilibrium of the gut microbiome is crucial for human health. Diet represents an important and generally accessible natural channel of...
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Long-term life history predicts current gut microbiome in a population-based cohort study
Extensive scientific and clinical microbiome studies have explored contemporary variation and dynamics of the gut microbiome in human health and...
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ENIGMA: an enterotype-like unigram mixture model for microbial association analysis
BackgroundOne of the major challenges in microbial studies is detecting associations between microbial communities and a specific disease. A...
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Chinese gut microbiota and its associations with staple food type, ethnicity, and urbanization
The gut microbiota could affect human health and disease. Although disease-associated microbiota alteration has been extensively investigated in the...
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Short term supplementation with cranberry extract modulates gut microbiota in human and displays a bifidogenic effect
Cranberry is associated with multiple health benefits, which are mostly attributed to its high content of (poly)phenols, particularly flavan-3-ols....
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Microbiome and Human Health: From Dysbiosis to Therapeutic Interventions
Human body is a complex system housing multiple biomes such as virome, microbiome, and eukaryome which governs human health. Unicellular archaea,...
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Diagnosis of Crohn’s disease and ulcerative colitis using the microbiome
BackgroundInflammatory bowel disease (IBD) is a multifactorial chronic inflammatory disease resulting from dysregulation of the mucosal immune...
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Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment
The human gut microbiome has been associated with several metabolic disorders including type 2 diabetes mellitus. Understanding metabolic changes in...
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Commensal Gastrointestinal Microbiota as a Complex Interactive Consortia
The commensal microbial population of the gastrointestinal tract is crucial to host health and wellbeing, not only because the microbes degrade...
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Age influences the temporal dynamics of microbiome and antimicrobial resistance genes among fecal bacteria in a cohort of production pigs
BackgroundThe pig gastrointestinal tract hosts a diverse microbiome, which can serve to select and maintain a reservoir of antimicrobial resistance...
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Optimizing ex vivo culture conditions to study human gut microbiome
The inter-individual variations of gut microbiome contribute to the different responses toward drug therapy among populations, develo** a reliable...
