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Directed proton transfer from Fo to F1 extends the multifaceted proton functions in ATP synthase
The role of protons in ATP synthase is typically considered to be energy storage in the form of an electrochemical potential, as well as an operating...
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Mitochondrial proton leak in cardiac aging
Age-associated diseases are becoming progressively more prevalent, reflecting the increased lifespan of the world’s population. However, the...
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Incomplete tricarboxylic acid cycle and proton gradient in Pandoravirus massiliensis: is it still a virus?
The discovery of Acanthamoeba polyphaga Mimivirus, the first isolated giant virus of amoeba, challenged the historical hallmarks defining a virus....
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Tools for analyzing protonation states and for tracing proton transfer pathways with examples from the Rb. sphaeroides photosynthetic reaction centers
Protons participate in many reactions. In proteins, protons need paths to move in and out of buried active sites. The vectorial movement of protons...
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Regulation of a vacuolar proton-pum** P-ATPase MdPH5 by MdMYB73 and its role in malate accumulation and vacuolar acidification
As the main organic acid in fruits, malate is produced in the cytoplasm and is then transported into the vacuole. It accumulates by vacuolar proton...
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Introduction of a Sodium-Binding Motif into Subunits a and c of Bacillus sp. PS3 Proton F-ATPase Does Not Result in Sodium Specificity of the Enzyme
AbstractIn bacteria, F-type ATPase (F-ATPase) plays a key role in bioenergetics and couples ATP synthesis/hydrolysis with the transport of ions (H + ...
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Proton-gated anion transport governs macropinosome shrinkage
Intracellular organelles change their size during trafficking and maturation. This requires the transport of ions and water across their membranes....
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Comparison of proton transfer paths to the QA and QB sites of the Rb. sphaeroides photosynthetic reaction centers
The photosynthetic bacterial reaction centers from purple non-sulfur bacteria use light energy to drive the transfer of electrons from cytochrome c ...
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The evolution of plant proton pump regulation via the R domain may have facilitated plant terrestrialization
Plasma membrane (PM) H + -ATPases are the electrogenic proton pumps that export H + from plant and fungal cells to acidify the surroundings and generate...
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Interaction of zinc and IAA alleviate aluminum-induced damage on photosystems via promoting proton motive force and reducing proton gradient in alfalfa
BackgroundIn acidic soils, aluminum (Al) competing with Zn results in Zn deficiency in plants. Zn is essential for auxin biosynthesis. Zn-mediated...
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Voltage-gated proton channels from fungi highlight role of peripheral regions in channel activation
Here, we report the identification and characterization of the first proton channels from fungi. The fungal proteins are related to animal...
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The effect of DC electric field on the elongation growth, proton extrusion and membrane potential of Zea mays L. coleoptile cells; a laboratory study
BackgroundIn this study, we investigated the effect of an electric field, with an intensity similar to that of the Earth’s field, on plant cells...
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Investigation of the Mechanism of Membrane Potential Generation by Heme-Copper Respiratory Oxidases in a Real Time Mode
AbstractHeme-copper respiratory oxidases are highly efficient molecular machines. These membrane enzymes catalyze the final step of cellular...
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Parameters for Induction Curves of Prompt and Delayed Fluorescence and Redox State of PSI–P700 for Birch and Linden Leaves in Various Urban Environments
AbstractThe photosynthetic characteristics of linden leaves ( Tilia cordata L.) and birches ( Betula verrukosa L.) growing near the city highways of...
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Generation and Fate of ROS in Mitochondria
Mitochondria, the powerhouse of the cell, perform the function of cellular respiration. The tricarboxylic acid cycle (TCA) and electron transport... -
Structure and mechanism of the proton-driven motor that powers type 9 secretion and gliding motility
Three classes of ion-driven protein motors have been identified to date: ATP synthase, the bacterial flagellar motor and a proton-driven motor that...
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Electroactive Microorganisms Involved in Power Generation in a Microbial Fuel Cell
Bio-electrocatalysts (microbes) are the most important components of microbial fuel cells (MFCs). Microbes act as a biocatalyst to generate... -
Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F1–Fo coupling
Mitochondrial adenosine triphosphate (ATP) synthase uses the proton gradient across the inner mitochondrial membrane to synthesize ATP. Structural...
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From cells to power cells: harnessing bacterial electron transport for microbial fuel cells (MFCs)
Microbial fuel cells (MFCs), which use bacterial electron transport mechanisms to generate energy, have become a viable technology for renewable...