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Biotechnological production of ectoine: current status and prospects
Ectoine is an important natural secondary metabolite in halophilic microorganisms. It protects cells against environmental stressors, such as...
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Usage of ectoine as a cryoprotectant for cryopreservation of lactic acid bacteria
Streptococcus thermophilus , the only Streptococcus species considered “Generally Recognized Safe”, has been used widely in the food industry. This...
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DNA scaffold assisted ectoine production in Escherichia coli
DNA scaffold that enhances the spatial proximity of enzymes and the local concentration of intermediates, is promising tools in optimizing...
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Metabolic engineering for improving ectoine production in Escherichia coli
Previously, we have developed an Escherichia coli strain MWZ003/pFT28- ectABC - EclysC* - aspDH - ppc3 in which the titer of ectoine reached 30.37 g/L with...
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Comparative genomic analysis of Halomonas campaniensis wild-type and ultraviolet radiation-mutated strains reveal genomic differences associated with increased ectoine production
Ectoine is a natural amino acid derivative and one of the most widely used compatible solutes produced by Halomonas species that affects both...
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γ-Aminobutyric acid (GABA) and ectoine (ECT) impacts with and without AMF on antioxidants, gas exchange attributes and nutrients of cotton cultivated in salt affected soil
Salinity stress is one of the major hurdles in agriculture which adversely affects crop production. It can cause osmotic imbalance, ion toxicity that...
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Ectoine Effect on Mechanical Properties of Vesicles in Aqueous Solution
The mechanical properties of the vesicles incorporated with ectoine were studied using atomic force microscope (AFM). The vesicles were prepared with...
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Whole genome sequencing of the halophilic Halomonas qaidamensis XH36, a novel species strain with high ectoine production
Here, we report the whole genome of a novel halophilic Halomonas species strain XH36 with high ectoine production potential. The genome was...
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Study of osmoadaptation mechanisms of halophilic Halomonas alkaliphila XH26 under salt stress by transcriptome and ectoine analysis
Halophilic bacteria such as the genus Halomonas are promising candidates in diverse industrial, agricultural and biomedical applications. Here, we...
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Metabolic engineering of Escherichia coli for efficient ectoine production
Ectoine is a high-value stabilizer and protective agent with various applications in enzyme industry, cosmetics, and biomedicine. In this study,...
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Promoter engineering for high ectoine production in a lower saline medium by Halomonas hydrothermalis Y2
ObjectivesFor the stress from fermenters, downstream processing equipment, and wastewater treatment to be alleviated, lowering salt-dependence in the...
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Develo** Liquid Rhizobium Inoculants with Enhanced Long-Term Survival, Storage Stability, and Plant Growth Promotion Using Ectoine Additive
AbstractLiquid microbial inoculants have recently received great attention due to their vital roles for sustainable agricultural practices. However,...
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Contribution of mechanosensitive channels to osmoadaptation and ectoine excretion in Halomonas elongata
For osmoadaptation the halophilic bacterium Halomonas elongata synthesizes as its main compatible solute the aspartate derivative ectoine. H. elongata ...
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Optimizing ectoine biosynthesis using response surface methodology and osmoprotectant applications
PurposeNumerous applications of compatible salts (osmolytes) as ectoine in food and pharmaceutical industries have been intensively increased...
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Metabolic Pathway Construction and Optimization of Escherichia coli for High-Level Ectoine Production
Ectoine is widely produced by various bacteria as a natural cell protectant against environment stress, e.g., osmotic and temperature stress. Its...
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Genome mining and physiological analyses uncover adaptation strategies and biotechnological potential of Virgibacillus dokdonensis T4.6 isolated from high-salt shrimp paste
Virgibacillus spp. stand out as a potent starter culture for accelerating the fermention of fish sauces and shrimp pastes. However, the underlying...
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Identification of novel halophilic/halotolerant bacterial species producing compatible solutes
Ectoine and hydroxyectoine are compatible solutes with enormous potential for use in the medical and cosmetic industries. Considering the excellent...
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Rational engineering of Halomonas salifodinae to enhance hydroxyectoine production under lower-salt conditions
AbstractHydroxyectoine is an important compatible solute that holds potential for development into a high-value chemical with broad applications....
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Machine learning methods for predicting the key metabolic parameters of Halomonas elongata DSM 2581 T
AbstractEctoine is generally produced by the fermentation process of Halomonas elongata DSM 2581 T , which is one of the primary industrial ectoine...
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Isolation, Identification, and Survival Strategy of the Halotolerant Strain Dietzia maris MX2 from the Yakshinskoe Mineral Salts Deposit
AbstractHalophilic and halotolerant microorganisms have a high biotechnological potential. They are producers of biologically active substances,...
