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Gap Junction Protein Connexin-43 in a Rat Dorsal Root Ganglion
AbstractThe study aimed at investigating the dynamics of the distribution and localization of the gap junction protein connexin-43 (Cx43) in rat...
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Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models
Friedreich ataxia (FA) is a rare, recessive neuro-cardiodegenerative disease caused by deficiency of the mitochondrial protein frataxin....
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Diabetes-induced electrophysiological alterations on neurosomes in ganglia of peripheral nervous system
Diabetes mellitus (DM) leads to medical complications, the epidemiologically most important of which is diabetic peripheral neuropathy (DPN)....
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Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis
BackgroundThe activated microglia have been reported as pillar factors in neuropathic pain (NP) pathology, but the molecules driving pain-inducible...
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Role of HCN channels in the functions of basal ganglia and Parkinson’s disease
Parkinson's disease (PD) is a motor disorder resulting from dopaminergic neuron degeneration in the substantia nigra caused by age, genetics, and...
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AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury
Regeneration after injury occurs in axons that lie in the peripheral nervous system but fails in the central nervous system, thereby limiting...
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Sensory neurons from dorsal root ganglia regulate endothelial cell function in extracellular matrix remodelling
BackgroundRecent physiological and experimental data highlight the role of the sensory nervous system in bone repair, but its precise role on...
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The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons
BackgroundAnnexin A1 (ANXA1) exerts anti-nociceptive effect through ANXA1 receptor formyl peptide receptor 2 (FPR2/ALX (receptor for lipoxin A4),...
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Spectral responses across a dorsal–ventral array of dermal sensilla in the medicinal leech
How do animals use visual systems to extract specific features of a visual scene and respond appropriately? The medicinal leech, Hirudo verbana , is a...
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Disengaging spinal afferent nerve communication with the brain in live mice
Our understanding of how abdominal organs (like the gut) communicate with the brain, via sensory nerves, has been limited by a lack of techniques to...
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Dorsal and ventral striatal functional connectivity shifts play a potential role in internet gaming disorder
Animal models suggest transitions from non-addictive to addictive behavioral engagement are associated with ventral-to-dorsal striatal shifts....
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Patch Clamp Analysis of Opioid-Induced Kir3 Currents in Mouse Peripheral Sensory Neurons Following Nerve Injury
Patch clamp is an electrophysiological technique that allows to analyze the activity of ion channels in neuronsNeurons. In this chapter, we provide a...
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Neuropathic pain development following nerve injury is mediated by SOX11-ARID1A-SOCS3 transcriptional regulation in the spinal cord
BackgroundNeuropathic pain, a complex condition originating from nervous system damage, remains a significant clinical challenge due to limited...
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Current Views on Perineurial Cells: Unique Origin, Structure, Functions
AbstractThis review aims to consolidate current views on the cells of one of the peripheral nerve sheath layers, perineurium. The relevance of the...
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Aging is associated with sex-specific alteration in the expression of genes encoding for neuroestradiol synthesis and signaling proteins in the mouse trigeminal somatosensory input
Pain perception is influenced by sex and aging, with previous studies indicating the involvement of aromatase, the estradiol synthase enzyme, in...
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Interactions of Eosinophils with Nerves
Eosinophils affect nerve structure and function in organs such as lungs and skin, which contributes to disease pathogenesis. We have developed...
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Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube
BackgroundThe dorsal domain of the neural tube is an excellent model to investigate the generation of complexity during embryonic development. It is...
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Methods and Applications of Campenot Trichamber Neuronal Cultures for the Study of Neuroinvasive Viruses
The development of compartmentalized neuron culture systems has been invaluable in the study of neuroinvasive viruses, including the alpha...
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Possible Involvement of Microglia in Establishing a Connection between the Central and Peripheral Nervous System
AbstractIn the present study, we studied localization and distribution of microgliocytes in the embryonic rat spinal cord (SC) during the...
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Ultrastructure of a swimming-type larva of Barentsia gracilis (Entoprocta, Coloniales)
The study of the microscopic anatomy of the larvae of Entoprocta is interesting in the context of determining the phylogenetic position of this...
