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Reaction–Diffusion Systems
Many models and simulation algorithms of intracellular kinetics are usually based on the premise that diffusion is so fast that the concentrations of... -
Single Microcolony Diffusion Analysis in Pseudomonas aeruginosa Biofilms
Diffusion phenomena play an important role during various stages of biofilm development. Hence, quantification of the diffusion coefficient of... -
Equivariant score-based generative diffusion framework for 3D molecules
BackgroundMolecular biology is crucial for drug discovery, protein design, and human health. Due to the vastness of the drug-like chemical space,...
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Protein translational diffusion as a way to detect intermolecular interactions
In this work, we analyze the information on the protein intermolecular interactions obtained from macromolecular diffusion. We have shown that the...
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Vesicle and reaction-diffusion hybrid modeling with STEPS
Vesicles carry out many essential functions within cells through the processes of endocytosis, exocytosis, and passive and active transport. This...
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An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity
The molecular mechanisms by which the endosomal sorting complexes required for transport (ESCRT) proteins contribute to the integrity of the nuclear...
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Evaluation of Automated Disk Diffusion Antimicrobial Susceptibility Testing Using Radian® In-Line Carousel
Antimicrobial susceptibility testing (AST) by disk diffusion provides an accurate image of bacterial growth, enabling the detection of culture...
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q-Diffusion leverages the full dimensionality of gene coexpression in single-cell transcriptomics
Unlocking the full dimensionality of single-cell RNA sequencing data (scRNAseq) is the next frontier to a richer, fuller understanding of cell...
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Measuring Molecular Diffusion in Self-Organizing Xenopus Extracts by Fluorescence Correlation Spectroscopy
The cytoplasm is densely packed with macromolecules and organelles, displaying viscoelastic properties at various scales. How biochemical reactions... -
Diffusion-driven fed-batch fermentation in perforated ring flasks
PurposeSimultaneous membrane-based feeding and monitoring of the oxygen transfer rate shall be introduced to the newly established perforated ring...
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Randomness, Diffusion, and Probability
Biological systems are not static, uniform, or deterministic, but rather dynamic, heterogeneous, and probabilistic. To understand and model such... -
Optimal dispersal and diffusion-enhanced robustness in two-patch metapopulations: origin’s saddle-source nature matters
A two-patch logistic metapopulation model is investigated both analytically and numerically focusing on the impact of dispersal on population...
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Analysis of plant cuticles and their interactions with agrochemical surfactants using a 3D printed diffusion chamber
BackgroundDecades of research is available on their effects of single component surfactant on active ingredient diffusion across plant cuticular...
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Host Cell Proteins with Cross Diffusion
A model is developed for the production of two proteins within a host cell that diffuse outward through the cell membrane with cross diffusion added... -
On the role of calcium diffusion and its rapid buffering in intraflagellar signaling
We have considered the realistic mechanism of rapid Ca 2+ (calcium ion) buffering within the wave of calcium ions progressing along the flagellar...
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Investigating Diffusion Dynamics and Interactions with Scanning Fluorescence Correlation Spectroscopy (sFCS)
Activation of immune cells and formation of immunological synapses (IS) rely critically on the reorganization of the plasma membrane. These highly... -
Roots of Cynodon dactylon increase gas permeability and gas diffusion coefficient of highly compacted soils
AimsThis study experimentally investigated the short-term (about 6 months) effects of roots of Cynodon dactylon on the gas permeability and gas...
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End-to-end protein–ligand complex structure generation with diffusion-based generative models
BackgroundThree-dimensional structures of protein–ligand complexes provide valuable insights into their interactions and are crucial for molecular...
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Retrospective rationalization of disparities between the concentration dependence of diffusion coefficients obtained by boundary spreading and dynamic light scattering
This study establishes the existence of substantial agreement between published results from traditional boundary spreading measurements (including...
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Earthworms and Arbuscular Mycorrhizal Fungi Alleviated Salt Stress in Maize Seedlings by Regulating the Root Endodermis Diffusion Barrier
Under salt stress, the root system is the first barrier in plant resistance. Endodermal suberin in plant roots can act as a diffusion barrier to...