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Persistent organic pollutants and mercury in a colony of Antarctic seabirds: higher concentrations in 1998, 2001, and 2003 compared to 2014 to 2016
Over decades, persistent organic pollutants (POPs) and trace metals like mercury (Hg) have reached the remotest areas of the world such as Antarctica...
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Modulatory role of RNA helicases in MBNL-dependent alternative splicing regulation
Muscleblind-like splicing regulators (MBNLs) activate or repress the inclusion of alternative splicing (AS) events, enabling the developmental...
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DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex
DExD/H-box helicase (DDX) 5 belongs to the DExD/H-box helicase family. DDX family members play differential roles in the regulation of innate...
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PAR regulation of photoprotection in Phaeodactylum tricornutum (Bacillariophyceae): Roles of doses and irradiances
Photosynthetic diatoms are exposed to a rapid and unexpected variations in light intensity that can modulate the contents of photosynthetic pigments...
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The DDX39B/FUT3/TGFβR-I axis promotes tumor metastasis and EMT in colorectal cancer
DDX39B is a member of the DEAD box (DDX) RNA helicase family required for nearly all cellular RNA metabolic processes. The exact role and potential...
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Photosynthetic Pigments in Diatoms
In this review, we present current knowledge of diatom photosynthetic pigments, along with some fresh insights into their physicochemical properties,... -
Production of Diadinoxanthin in an Intensive Culture of the Diatomaceous Alga Cylindrotheca closterium (Ehrenb.) Reimann et Lewin. and Its Proapoptotic Activity
AbstractThe production of diadinoxanthin and its cytostatic activity in an intensive culture of C. closterium has been estimated via molecular...
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Diversity of MLE Helicase Functions in the Regulation of Gene Expression in Higher Eukaryotes
AbstractThe Drosophila melanogaster Maleless (MLE) protein is a conserved helicase involved in a wide range of gene expression regulation processes....
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When DNA-damage responses meet innate and adaptive immunity
When cells proliferate, stress on DNA replication or exposure to endogenous or external insults frequently results in DNA damage. DNA-Damage Response...
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Screening and functional verification of drought resistance-related genes in castor bean seeds
Drought is one of the natural stresses that greatly impact plants. Castor bean ( Ricinus communis L.) is an oil crop with high economic value. Drought...
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Influence of exogenous phytohormone supplementation on the pigment and fatty acid content of three marine diatoms
Diatoms are ubiquitous photosynthetic microorganisms with great potential for biotechnological applications. However, their commercialisation is...
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Interferon-induced transmembrane protein-1 competitively blocks Ephrin receptor A2-mediated Epstein–Barr virus entry into epithelial cells
Epstein–Barr virus (EBV) can infect both B cells and epithelial cells (ECs), causing diseases such as mononucleosis and cancer. It enters ECs via...
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Role of Nanoparticles in Remediation of Contaminated Soil
The global population is increasing day by day promoting industrialization. Various pollutants like pesticides, heavy metals, hydrocarbons,... -
A novel role for KIFC1-MYH9 interaction in triple-negative breast cancer aggressiveness and racial disparity
African American (AA) women are twice as likely to develop triple-negative breast cancer (TNBC) as women of European descent. Additionally, AA women...
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DExD/H-box helicases: multifunctional regulators in antiviral innate immunity
DExD/H-box helicases play critical roles in multiple cellular processes, including transcription, cellular RNA metabolism, translation, and...
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Time-resolved Small-RNA Sequencing Identifies MicroRNAs Critical for Formation of Embryonic Stem Cells from the Inner Cell Mass of Mouse Embryos
AbstractCells of the inner cell mass (ICM) acquire a unique ability for unlimited self-renewal during transition into embryonic stem cells (ESCs) in...
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Impact of N6-methyladenosine (m6A) modification on immunity
N6-methyl-adenosine (m 6 A) is the most prevalent modification on mRNAs and long noncoding RNAs (lnRNAs) in higher eukaryotes. Modulation of m 6 A relies...
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Phase separation of Ddx3xb helicase regulates maternal-to-zygotic transition in zebrafish
Vertebrate embryogenesis involves a conserved and fundamental process, called the maternal-to-zygotic transition (MZT), which marks the switch from a...
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DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath
The axonemal dynein arms (outer (ODA) and inner dynein arms (IDAs)) are multiprotein structures organized by light, intermediate, light intermediate...