Search
Search Results
-
Effects of tryptophan and phenylalanine on tryptophol production in Saccharomyces cerevisiae revealed by transcriptomic and metabolomic analyses
Tryptophol (TOL) is a metabolic derivative of tryptophan (Trp) and shows pleiotropic effects in humans, plants and microbes. In this study, the...
-
Cell death induced by mycotoxin fumonisin B1 is accompanied by oxidative stress and transcriptional modulation in Arabidopsis cell culture
Key messageFumonisin B 1 induces rapid programmed cell death in Arabidopsis cells, oxidative and nitrosative bursts, and differentially modulates...
-
Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs
BackgroundMidbrain dopaminergic (DA) progenitors derived from human pluripotent stem cells are considered to be a promising treatment for Parkinson’s...
-
Investigating the role of the transcriptional regulator Ure2 on the metabolism of Saccharomyces cerevisiae: a multi-omics approach
AbstractUre2 regulates nitrogen catabolite repression in Saccharomyces cerevisiae . Deletion of URE2 induces a physiological state mimicking the...
-
Comparative transcriptome analyses reveal two distinct transcriptional modules associated with pollen shedding time in pine
BackgroundSeasonal flowering time is an ecologically and economically important trait in temperate trees. Previous studies have shown that...
-
Origination and selection of ABCDE and AGL6 subfamily MADS-box genes in gymnosperms and angiosperms
BackgroundThe morphological diversity of flower organs is closely related to functional divergence within the MADS-box gene family. Bryophytes and...
-
The birth, evolution and death of metabolic gene clusters in fungi
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways involved in ecologically specialized or accessory functions....
-
Nitrogen Assimilation Pathways in Budding Yeasts
The element nitrogen is an essential macronutrient for all living organisms. Like other microorganisms, budding yeasts (phylum Ascomycota, subphylum...
-
Identification of the fitness determinants of budding yeast on a natural substrate
The budding yeasts are prime models in genomics and cell biology, but the ecological factors that determine their success in non-human-associated...
-
Molecular diversity and biogeography of Philippine foliose Bangiales (Rhodophyta)
Species circumscription based on phenotypes has frequently masked the actual species diversity in foliose Bangiales. Application of DNA sequence...
-
Metabolic differentiation of surface and invasive cells of yeast colony biofilms revealed by gene expression profiling
BackgroundYeast infections are often connected with formation of biofilms that are extremely difficult to eradicate. An excellent model system for...
-
Arabidopsis DAL1 and DAL2, two RING finger proteins homologous to Drosophila DIAP1, are involved in regulation of programmed cell death
Programmed cell death (PCD) is a precise, genetically controlled cellular process with important roles in plant growth, development, and response to...
-
Functional Genomics of Seed Development in Cereals
Seeds are the product of sexual reproduction in flowering plants. The seeds of cereals are the main source of staple food, animal feed and the raw...
-
Ectopic expression of a truncated Pinus radiata AGAMOUS homolog (PrAG1) causes alteration of inflorescence architecture and male sterility in Nicotiana tabacum
Plant MADS-box genes of the AG/PLE subfamily control the identity of sexual organs. An AG -homologous gene ( PrAG1 ) was characterized in the Pinus...
-
Functional Genomics of Flowering Time in Trees
Genomics of floral induction and flower development in trees is much more complex than in annual/biennial herbaceous plants. Detailed genetic models...
-
Effects of nitrogen catabolite repression and di-ammonium phosphate addition during wine fermentation by a commercial strain of S. cerevisiae
Two deletion mutants expected to be defective in nitrogen catabolite repression (NCR) were constructed in a commercial wine yeast background M2: a ure2 ...
-
A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress
BackgroundIn aerobically grown cells, iron homeostasis and oxidative stress are tightly linked processes implicated in a growing number of diseases....
-
Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames)
BackgroundBacillus anthracis is the causative agent of anthrax and a potential bioterrorism threat. Here we report the biochemical and structural...
-
Operons
Operons (clusters of co-regulated genes with related functions) are common features of bacterial genomes. More recently, functional gene clustering...
-
Comparing the transcriptomes of wine yeast strains: toward understanding the interaction between environment and transcriptome during fermentation
System-wide “omics” approaches have been widely applied to study a limited number of laboratory strains of Saccharomyces cerevisiae . More recently,...
