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A zero-inflated model for spatiotemporal count data with extra zeros: application to 1950–2015 tornado data in Kansas
In many tornado climate studies, the number of tornado touchdowns is often the primary outcome of interest. These outcome measures are usually...
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Normalizing need not be the norm: count-based math for analyzing single-cell data
Counting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell...
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Development of resilience indicator traits based on daily step count data for dairy cattle breeding
BackgroundResilient animals are minimally affected by disturbances, such as diseases and heat stress, and quickly recover. Daily activity data can...
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Gene count normalization in single-cell imaging-based spatially resolved transcriptomics
BackgroundRecent advances in imaging-based spatially resolved transcriptomics (im-SRT) technologies now enable high-throughput profiling of targeted...
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GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership
Parts-based representations, such as non-negative matrix factorization and topic modeling, have been used to identify structure from single-cell...
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Randomized quantile residuals for diagnosing zero-inflated generalized linear mixed models with applications to microbiome count data
BackgroundFor differential abundance analysis, zero-inflated generalized linear models, typically zero-inflated NB models, have been increasingly...
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Bayesian and Classical Prediction Models for Categorical and Count Data
In this chapter, we explain, under a Bayesian framework, the fundamentals and practical issues for implementing genomic prediction models for...
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Investigation of homocysteine, D-dimer and platelet count levels as potential predictors of thrombosis risk in COVID-19 patients
Thrombosis plays an important role in induction of Coronavirus disease 19 (COVID-19) complications including heart attack and stroke. Reliable...
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High molecular risk variants, severe thrombocytopenia and large unstained cells count affect the outcome in primary myelofibrosis
Apart from the driver mutations, high molecular risk (HMR) variants and other factors have been reported to influence the prognosis of primary...
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Neutrophil, lymphocyte count, and neutrophil to lymphocyte ratio predict multimorbidity and mortality—results from the Baltimore Longitudinal Study on Aging follow-up study
Immunosenescence is the age-related changes in the immune system, namely, progressively higher levels of circulating inflammatory markers,...
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Temporal beta diversity of bird species using the point count method indicates predominance of turnover over nestedness in an Atlantic Forest site
Morning is the ideal period for sampling bird communities in tropical forests, but there is a vocal decline in birds over time. We investigate the...
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Assessing total erythrocyte count as a potential attribute for estimating hemoglobin in Cholistani cattle
The main objective of the study was to confirm whether a specific and constant interrelationship exists between total erythrocyte count (TEC) and...
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Relationship between faecal egg count and health status in Nguni goats reared on semi-arid rangelands
Gastrointestinal parasitism is a major constraint to goat productivity, particularly in resource-limited production systems. The objective of the...
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Effect of the Somatic Cell Count, Taking into Account Their Morphological Differentiation, on Cow Milk’s Component Composition
AbstractThis paper examines the dynamics of milk component’s composition in dependence to the udder health status diagnosed in Holstein and Ayrshire...
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scDesign2: a transparent simulator that generates high-fidelity single-cell gene expression count data with gene correlations captured
A pressing challenge in single-cell transcriptomics is to benchmark experimental protocols and computational methods. A solution is to use...
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Space-efficient representation of genomic k-mer count tables
Motivationk -mer counting is a common task in bioinformatic pipelines, with many dedicated tools available. Many of these tools produce in output k -me...
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Reduced neural progenitor cell count and cortical neurogenesis in guinea pigs congenitally infected with Toxoplasma gondii
Toxoplasma (T.) gondii is an obligate intracellular parasite with a worldwide distribution. Congenital infection can lead to severe pathological...
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AMULET: a novel read count-based method for effective multiplet detection from single nucleus ATAC-seq data
Detecting multiplets in single nucleus (sn)ATAC-seq data is challenging due to data sparsity and limited dynamic range. AMULET (ATAC-seq MULtiplet...
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Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and risk factors associated with high total bacterial count in bulk tank milk from dairy farms in Colombia
The objective of the study was to evaluate the frequency and genetic characteristics of ESBL-producing Escherichia coli and Klebsiella spp. and the...
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Genetic variants associated with platelet count are predictive of human disease and physiological markers
Platelets play an important role in hemostasis and other aspects of vascular biology. We conducted a meta-analysis of platelet count GWAS using data...
