Search
Search Results
-
Conjugative type IV secretion systems enable bacterial antagonism that operates independently of plasmid transfer
Bacterial cooperation and antagonism mediated by secretion systems are among the ways in which bacteria interact with one another. Here we report the...
-
Systematic investigation of recipient cell genetic requirements reveals important surface receptors for conjugative transfer of IncI2 plasmids
Bacterial conjugation is a major horizontal gene transfer mechanism. While the functions encoded by many conjugative plasmids have been intensively...
-
Conjugative transfer of streptococcal prophages harboring antibiotic resistance and virulence genes
Prophages play important roles in the transduction of various functional traits, including virulence factors, but remain debatable in harboring and...
-
CRISPR-Cas3 and type I restriction-modification team up against blaKPC-IncF plasmid transfer in Klebsiella pneumoniae
ObjectiveWe explored whether the Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas and restriction-modification (R-M) systems are...
-
Characterization and Abundance of Plasmid-Dependent Alphatectivirus Bacteriophages
Antimicrobial resistance (AMR) is a major public health threat, exacerbated by the ability of bacteria to rapidly disseminate antimicrobial...
-
A self-transmissible plasmid from a hyperthermophile that facilitates genetic modification of diverse Archaea
Conjugative plasmids are self-transmissible mobile genetic elements that transfer DNA between host cells via type IV secretion systems (T4SS). While...
-
Oxytetracycline and heavy metals promote the migration of resistance genes in the intestinal microbiome by plasmid transfer
Horizontal gene transfer (HGT) has been considered the most important pathway to introduce antibiotic resistance genes (ARGs), which seriously...
-
Evaporation-induced hydrodynamics control plasmid transfer during surface-associated microbial growth
Droplet evaporation is a general process in unsaturated environments that results in micro-scale hydrodynamic flows which in turn determine the...
-
Detection and classification of the integrative conjugative elements of Lactococcus lactis
Lactococcus lactis is widely applied by the dairy industry for the fermentation of milk into products such as cheese. Adaptation of L. lactis to the...
-
Molecular Genetic and Functional Analysis of the Rap-Phr Signal System of the Plasmid pBS72 of Bacillus subtilis Isolates
Abstract —The functional characteristics of the Rap‒Phr quorum sensing signal system of the plasmid pBS72 were investigated. Phylogenetic relationship...
-
Gene Transfer
In addition to vertical gene transfer between generations, microbes often transfer their genes horizontally. Horizontal gene transfer contributes...
-
Highly efficient gene transfer in the mouse gut microbiota is enabled by the Incl2 conjugative plasmid TP114
The gut microbiota is a suspected hotspot for bacterial conjugation due to its high density and diversity of microorganisms. However, the...
-
IS6 family insertion sequences promote optrA dissemination between plasmids varying in transfer abilities
AbstractPlasmids are the primary vectors for intercellular transfer of the oxazolidinone and phenicol cross-resistance gene optrA , while insertion...
-
Cooperative antibiotic resistance facilitates horizontal gene transfer
The rise of β-lactam resistance among pathogenic bacteria, due to the horizontal transfer of plasmid-encoded β-lactamases, is a current global health...
-
Droplet size and surface hydrophobicity enhance bacterial plasmid transfer rates in microscopic surface wetness
Conjugal plasmids constitute a major engine for horizontal gene transfer in bacteria, and are key drivers of the spread of antibiotic resistance,...
-
Within-patient evolution of plasmid-mediated antimicrobial resistance
Antimicrobial resistance (AMR) in bacteria is a major threat to public health; one of the key elements in the spread and evolution of AMR in clinical...
-
Evaporation-induced hydrodynamics promote conjugation-mediated plasmid transfer in microbial populations
Conjugative plasmids bestow important traits to microbial communities, such as virulence, antibiotic resistance, pollutant biotransformation, and...
-
Nonnutritive sweeteners can promote the dissemination of antibiotic resistance through conjugative gene transfer
Antimicrobial resistance (AMR) poses a worldwide threat to human health and biosecurity. The spread of antibiotic resistance genes (ARGs) via...
-
A native conjugative plasmid confers potential selective advantages to plant growth-promoting Bacillus velezensis strain GH1-13
The conjugative plasmid (pBV71) possibly confers a selective advantage to Bacillus velezensis strain GH1-13, although a selective marker gene is yet...
-
Hyper-stimulation of Pyrococcus furiosus CRISPR DNA uptake by a self-transmissible plasmid
Pyrococcus furiosus is a hyperthermophilic archaeon with three effector CRISPR complexes (types I-A, I-B, and III-B) that each employ crRNAs derived...
