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Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases
N6-methyladenosine (m 6 A) modification, catalyzed by methyltransferase complexes (MTCs), plays many roles in multifaceted biological activities. As...
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DGH-GO: dissecting the genetic heterogeneity of complex diseases using gene ontology
BackgroundComplex diseases such as neurodevelopmental disorders (NDDs) exhibit multiple etiologies. The multi-etiological nature of complex-diseases...
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Deep migration learning-based recognition of diseases and insect pests in Yunnan tea under complex environments
BackgroundThe occurrence, development, and outbreak of tea diseases and pests pose a significant challenge to the quality and yield of tea,...
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Genetic regulation of m6A RNA methylation and its contribution in human complex diseases
N 6 -methyladenosine (m 6 A) has been established as the most prevalent chemical modification in message RNA (mRNA), playing an essential role in...
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Identifying critical transitions in complex diseases
Mortality and the burden of diseases worldwide continue to reach substantial numbers with societal development and urbanization. In the face of...
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Diseases of Sage
Sage (Salvia officinalis), also known as common, garden, or Spanish sage, is a perennial, shrubby, culinary herb. It is used as a flavoring, for its...
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Systems Biology and Human Diseases
Systems biology is concerned with the analysis and modelling of complex biological systems using computational and mathematical tools. This deals...
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Large-Scale Gene Expression in Monogenic and Complex Genetic Diseases
This chapter will focus on large-scale gene expression in monogenic and complex genetic diseases with an emphasis on immunological diseases....
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Diseases of Chickpea
Chickpeas are one of the most economically important legumes and a rich source of carbohydrates, proteins, vitamins, minerals, and fiber. Chickpea is...
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Cardioproteomics: Insights on Cardiovascular Diseases
Cardiovascular diseases (CVDs) remain a global health challenge and are the leading cause of deaths worldwide. Proteomics has emerged as a valuable...
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Diseases of Pea
Pea (Pisum sativum) is an ancient crop, domesticated in the Fertile Crescent, which has been spread across the temperate regions of the globe. There...
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Secrets and lies of host–microbial interactions: MHC restriction and trans-regulation of T cell trafficking conceal the role of microbial agents on the edge between health and multifactorial/complex diseases
Here we critically discuss data supporting the view that microbial agents (pathogens, pathobionts or commensals alike) play a relevant role in the...
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Diseases of Seed Spices
Diseases caused by fungal pathogens are important biotic constraints in the production of seed spices in India. A few bacteria and viruses also cause...
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Diseases of Rosemary
Rosemary (Rosmarinus officinalis) is a shrubby, perennial culinary herb which can also be grown as a landscape plant. It is used as a flavoring and...
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Complex Disease Prediction Using Systems Biology Approach
Imagine a mirror maze this complex breakthrough can be analogous to what many researchers face when trying to decipher the intricacy and...
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Diseases of Mint
Mint, the genus Mentha, is comprised of 18 species and 11 hybrids (Mentha: an overview of its classification and relationships. In: Lawrence BM (d.)...
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Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases
Accumulating evidence suggests that endothelial cells can be useful therapeutic targets. One of the potential targets is an endothelial cell-specific...
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Diseases of Sweetpotato
Sweetpotato is the sixth most important food crop globally. Whereas in developed countries like Canada, Europe, and the United States, it is...
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Systems Biology Consortium for Infectious Diseases
Infectious diseases continue to be major health concerns worldwide. In the twenty-first century, more people are at risk of life-threatening acute...
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Diseases of Parsley
Parsley (Petroselinum crispum) is an important culinary ingredient and garnish (dried or fresh leaves) used worldwide. Parsley profitability can be...