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Evolutionary Structure Conservation and Covariance Scores
Effective homology search for non-coding RNAs is frequently not possible via sequence similarity alone. Current methods leverage evolutionary...
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Modified Nucleotides and RNA Structure Prediction
Nucleotide modifications are occurrent in all types of RNA and play an important role in RNA structure formation and stability. Modified bases not...
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Classified Dynamic Programming in RNA Structure Analysis
Analysis of the folding space of RNA generally suffers from its exponential size. With classified Dynamic Programming algorithms, it is possible to...
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Probing the RNA Structure-Dependent RNA Regulations and Functions
RNAs form complex structures in vivo to perform diverse functions. These RNA structures dynamically change in response to internal cellular...
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Probing Techniques of Secondary and Tertiary RNA Structure and a Case Study for RNA G-Quadruplexes
Like proteins, an RNA is only functional when it is folded into its native conformation and adopts a specific secondary and tertiary structure....
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Modified Nucleosides as RNA Components. Structure, Biological Role and Drug Design
More than 100 modified nucleosides with different structures and functions are known as components of nucleic acids. Carbohydrate-modified...
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Characterization of the mitochondrial genomes of the Mexican endemic bats Corynorhinus mexicanus and Corynorhinus leonpaniaguae (Chiroptera: Vespertilionidae)
BackgroundThe genus Corynorhinus is composed of four recognized species: C. rafinesquii , C. townsendii , C. mexicanus , and C. leonpaniaguae , the...
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Discovery of a tRNA-like base sequence in the coronavirus genome and possible mechanism of action
BackgroundThe question of whether the coronavirus genome contain as-yetununderstood genetic component.
Purpose (Objective)Elucidate the novel...
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RNA structure: implications in viral infections and neurodegenerative diseases
RNA is an intermediary between DNA and protein, a catalyzer of biochemical reactions, and a regulator of genes and transcripts. RNA structures are...
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De novo assembly of the complete mitochondrial genome of Mycetophylax simplex Emery, 1888 through organelle targeting revels no substantial expansion of gene spacers, but rather some slightly shorter genes
Mitochondria play a key role in cell biology and have their own genome, residing in a highly oxidative environment that induces faster changes than...
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Characterization of complete mitochondrial genomes of five noctuoid moths (Lepidoptera: Noctuoidea) and their phylogenetic implications
In this study, the complete mitochondrial genomes of five noctuoid moth species, namely, Paectes cristatrix , Hemichloridia euprepia , Trigonodes...
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Biosynthesis and function of 1-methyladenosine in transfer RNA
Determining the function of single nucleotide modifications in tRNA has been elusive because so many tRNA modification enzymes are not essential for...
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Characterization of the complete mitochondrial genome of Ergasilus anchoratus Markevich, 1946 (Ergasilidae) and phylogeny of Copepoda
The mitochondrial (mt) genome can provide data for phylogenetic analyses and evolutionary biology. Herein, we sequenced and annotated the complete mt...
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RNA Structure Prediction
One of the significant forms of molecules present in living cells is ribonucleic acid (RNA). RNA structural elements moderate various biological...
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Comparative mitochondrial genome analysis of three leafhopper species of the genus Abrus Dai & Zhang (Hemiptera: Cicadellidae: Deltocephalinae) from China with phylogenetic implication
BackgroundThe phylogenetic position and classification of Athysanini are poorly defined, as it includes a large group of polyphyletic genera that...
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Littoraria flava (Gastropoda: Littorinidae) mitogenome: phylogenetic considerations within the Caenogastropoda and evidence of microscale local adaptation
Littorinids, such as Littoraria flava , are attractive models for local adaptation studies in the rocky shore intertidal zone. The wide heterogeneity...
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The first complete mitochondrial genome sequences for Ulidiidae and phylogenetic analysis of Diptera
BackgroundTetanops sintenisi is a pest that mainly damages the root of quinoa ( Chenopodium quinoa ) and it is first discovered in China in 2018.
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The mitochondrial genome of Heterosentis pseudobagri (Wang & Zhang, 1987) Pichelin & Cribb, 1999 reveals novel aspects of tRNA genes evolution in Acanthocephala
BackgroundAcanthocephala is a clade of obligate endoparasites whose mitochondrial genomes (mitogenomes) and evolution remain relatively poorly...
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Mitogenome of Knodus borki (Cypriniformes: Characidae): genomic characterization and phylogenetic analysis
BackgroundThe taxonomic status of Knodu in the family Characidae is not yet clear. This study aimed to address this by sequencing and annotating Knodu...
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Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
BackgroundThe presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding...
