Search
Search Results
-
Mathematical Models of Chiral Symmetry-breaking – A Review of General Theories, and Adiabatic Approximations of the APED System
We review the literature surrounding chiral symmetry-breaking in chemical systems, with a focus on understanding the mathematical models underlying...
-
Symmetry Breaking by Consecutive Amplification: Efficient Paths to Homochirality
To understand chiral symmetry breaking on the molecular level, we developed a method to efficiently investigate reaction kinetics of single...
-
Chiral Symmetry Breaking in Large Peptide Systems
Chiral symmetry breaking in far from equilibrium systems with large number of amino acids and peptides, like a prebiotic Earth, was considered. It...
-
Spontaneous Emergence of Transient Chirality in Closed, Reversible Frank-like Deterministic Models
To explore abiotic theories related to the origin of biomolecular homochirality, we analyze two entirely reversible kinetic models composed of an...
-
Asymmetric Autocatalysis as an Efficient Link Between the Origin of Homochirality and Highly Enantioenriched Compounds
Biological homochirality of essential components such as L -amino acids and D -sugars is prerequisite for the emergence, evolution and the maintenance...
-
Evolutionary Approach to Biological Homochirality
We study a very simple linear evolutionary model based on distribution of protocells by total enantiomeric excess and without any mutual inhibition...
-
Molecular Self-Assembly as a Trigger of Life Origin and Development
The origin and reason for the homochirality of living cells go with the problem of a relatively narrow spectrum of the actual biological monomers...
-
Biological Homochirality and the Search for Extraterrestrial Biosignatures
Most amino acids and sugar molecules occur in mirror, or chiral, images of each other, knowns as enantiomers. However, life on Earth is mostly...
-
Chiral Symmetry Breaking in Peptide Systems During Formation of Life on Earth
Chiral symmetry breaking in complex chemical systems with a large number of amino acids and a large number of similar reactions was considered. It...
-
From Dissipative Structures to Biological Evolution: A Thermodynamic Perspective
In the second half of the twentieth century, it was recognized that systems far from thermodynamic equilibrium can spontaneously self-organize into...
-
On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review
By paraphrasing one of Kipling’s most amazing short stories ( How the Leopard Got His Spots ), this article could be entitled “How Sugars Became...
-
Recent advances in the application of [2 + 2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products
Cyclobutanes are distributed widely in a large class of natural products featuring diverse pharmaceutical activities and intricate structural...
-
Circular Dichroism
In our analysis of how an electromagnetic radiation field interacts with electrons, we have, to this point, considered only the oscillating electric...
-
Mechanisms Underlying Variations in the Dentition Asymmetry of Asian Snail-Eating Snakes
The Bilateria are generally characterized by lateral symmetry of external morphology. A remarkable exception is the mandibular teeth of Asian...
-
Magnetic Circular Dichroism in Archean Stratospheric Oxygen: Enantiomeric Excess of Amino Acids Produced in Volcanic Plumes
While there is consensus that Archean atmosphere was anoxic with O 2 pressure, p (O 2 ) <10 -6 PAL (present atmospheric level) at sea-level, evidence...
-
Chiral Monomers Ensure Orientational Specificity of Monomer Binding During Polymer Self-Replication
Biomolecular homochirality is universally observed in living systems but the molecular and evolutionary dynamics that led to its emergence are...
-
Characterization of Peptide-Based Nanomaterials
In this chapter, we will thoroughly discuss characterization techniques used to elucidate the exact structure and define properties of peptide-based...
-
Quadruplex World
The RNA world hypothesis relies on the double-helix complementarity principle for both replication and catalytic activity of RNA. However, the de...
-
Mechanical regulation of early vertebrate embryogenesis
Embryonic cells grow in environments that provide a plethora of physical cues, including mechanical forces that shape the development of the entire...
