Search
Search Results
-
Applications of Circular Dichroism Spectroscopy in Studying Protein Folding, Stability, and Interaction
Circular dichroism (CD) spectroscopy has been extensively used to determine the structure and folding of proteins. It provides valuable information...
-
Applications of biaryl cyclization in the synthesis of cyclic enkephalin analogs with a highly restricted flexibility
A series of 10 cyclic, biaryl analogs of enkephalin, with Tyr or Phe residues at positions 1 and 4, were synthesized according to the Miyaura...
-
Cadmium Reduction in Spring Wheat: Root Exudate Composition Affects Cd Partitioning Between Roots and Shoots
Cadmium (Cd) in cereals is one of the major sources of Cd intake by human diets, and solutions to reduce Cd concentrations in wheat still need to be...
-
Cadmium and copper-induced metabolic and proteomic changes in the root tip during early maize growth
In this study, the metabolic adjustments performed by maize ( Zea mays L.) seminal roots exposed to 25 µM Cd 2+ or 25 µM Cu 2+ at pre-emergence are...
-
Release of frustration drives corneal amyloid disaggregation by brain chaperone
TGFBI-related corneal dystrophy (CD) is characterized by the accumulation of insoluble protein deposits in the corneal tissues, eventually leading to...
-
Three new phthalide derivatives from culture broth of Dentipellis fragilis and their cytotoxic activities
Three new phthalide derivatives ( 1 ‒ 3 ) together with two known compounds, erinaceolactone B ( 4 ) and hericerin III ( 5 ), were isolated from the culture...
-
Recombinant production of human antimicrobial peptide LL- 37 and its secondary structure
Antimicrobial peptides, including the human cathelicidin LL-37, offer a possible solution to the global problem of bacterial resistance to...
-
A novel aureothin diepoxide derivative from Streptomyces sp. NIIST-D31 strain
A novel vicinal diepoxide of alloaureothin was isolated from Streptomyces sp. NIIST-D31 strain along with three carboxamides, p -aminobenzoic acid and...
-
Development of a System for Biosynthesis, Isolation and Purification of the Holoform of Recombinant Human Neuroglobin and Its Characteristics
Abstract—An efficient system for the biosynthesis, isolation and purification of recombinant human neuroglobin has been developed and optimized,...
-
Citrinadin C, a new cytotoxic pentacyclic alkaloid from marine-derived fungus Penicillium citrinum
A new cytotoxic pentacyclic alkaloid, citrinadin C ( 1 ), together with four known compounds ( 2 – 5 ), were isolated from deep-sea-derived fungus Penicilliu...
-
Linear polyketides produced by co-culture of Penicillium crustosum and Penicillium fellutanum
Two new polyketides, penifellutins A ( 1 ) and B ( 2 ), possessing a 22 carbon linear skeleton, were isolated from a co-culture of the deep-sea-derived...
-
Differences in Exudates Between Strains of Chlorella sorokiniana Affect the Interaction with the Microalga Growth-Promoting Bacteria Azospirillum brasilense
The microalga Chlorella sorokiniana and the microalgae growth-promoting bacteria (MGPB) Azospirillum brasilense have a mutualistic interaction that...
-
A new metabolite, mannogeranylnerol, specifically produced at body temperature by Schizophyllum commune, a causative fungus of human mycosis
Schizophyllum commune is a causative fungus of human mycosis. Its metabolites produced at 27 °C were compared with those produced at 37 °C, to obtain...
-
(R/S)-lactate/2-hydroxybutyrate dehydrogenases in and biosynthesis of block copolyesters by Ralstonia eutropha
AbstractBacterial polyhydroxyalkanoates (PHAs) are promising bio-based biodegradable polyesters. It was recently reported that novel PHA block...
-
Biochemical Characterization of the Integrin Interactome
More than 250 proteins are associated with the formation of integrin adhesion complexes involving a vast number of complex interactions between them....
-
Biomolecular docking interactions, cytotoxicity and antioxidant property evaluations with novel Mn(II), Ni(II), Cd(II) and Pb(II) Schiff base ligand complexes: Synthesis and characterization
The development of Schiff base-centered medical chemistry in conjunction with the use of less-expensive transition metals with high pharmacological...
-
Aldsulfin, a novel unusual anti-mannheimiosis epithiodiketopiperazine antibiotic produced by Lasiodiplodia pseudotheobromae FKI-4499
An anti-mannheimiosis agent, aldsulfin, was isolated from a culture broth of the fungus Lasiodiplodia pseudotheobromae FKI-4499, together with a...
-
Mechanism of MyD88S mediated signal termination
BackgroundA universal adaptor protein, MyD88, orchestrates the innate immune response by propagating signals from toll-like receptors (TLRs) and...
-
Sealutomicins, new enediyne antibiotics from the deep-sea actinomycete Nonomuraea sp. MM565M-173N2
A Nonomuraea sp. strain MM565M-173N2 was isolated from deep-sea sediment off the Sanriku coast, and new antibiotics were evaluated against...
-
Adoption of A–Z Junctions in RNAs by Binding of Zα Domains
While DNA and RNA helices often adopt the canonical B- or A-conformation, the fluid conformational landscape of nucleic acids allows for many higher...