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Online Detection of Catecholamine Release from the Perfused Rat Adrenal Gland
Retrogradely perfused adrenal glands have historically served for establishing many of our current knowledge on the stimulus-secretion coupling...
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Glucose enhances catecholamine-stimulated lipolysis via increased glycerol-3-phosphate synthesis in 3T3-L1 adipocytes and rat adipose tissue
BackgroundDuring lipolysis, triglyceride (TG) are hydrolyzed into a glycerol and fatty acids in adipocyte. A significant portion of the fatty acids...
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The Reaction of CD68+, CD45RO+, and Catecholamine-Containing Spleen Cells to the Development of a Colon Tumor in Offspring of Splenectomized Female Rats
Abstract—A high prevalence of immunodeficiency states has been a global challenge in recent decades. There are numerous factors that lead to immune...
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Near-infrared catecholamine nanosensors for high spatiotemporal dopamine imaging
Dopamine neuromodulation of neural synapses is a process implicated in a number of critical brain functions and diseases. Development of protocols to...
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Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues
Dopamine is an important neurotransmitter that regulates numerous essential functions, including cognition and voluntary movement. As such, it serves...
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Role of Free Catecholamine in Thiol-Ene Crosslinking for Hyaluronic Acid Hydrogels with High Loading Efficiency of Anticancer Drugs
Background:Hyaluronic acid (HA) is a widely used polysaccharide in biomedical field because of its excellent biocompatibility. Its chemical structure...
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Real Time Recording of Perifused Chromaffin Cells
Amperometry is an electrochemical method based on the oxidation or reduction of molecules. Many secretion products, including catecholamines, contain...
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Determination of Catecholamines in a Small Volume (25 μL) of Plasma from Conscious Mouse Tail Vein
The determination of plasma catecholamine levels is commonly used as a measure of the sympathetic nervous system’s response to stress and is highly...
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Methodologies for Detecting Quantal Exocytosis in Adrenal Chromaffin Cells Through Diamond-Based MEAs
Diamond-based multiarray sensors are suitable to detect in real-time exocytosis and action potentials from cultured, spontaneously firing chromaffin...
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The Saga of Catecholamine and GABA Through Prospecting Stress Tolerance in Plants
Plants are subjected to various abiotic stress factors. They respond to these circumstances or in long term response, they change their metabolic...
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MiR-150 blunts cardiac dysfunction in mice with cardiomyocyte loss of β1-adrenergic receptor/β-arrestin signaling and controls a unique transcriptome
The β 1 -adrenergic receptor (β 1 AR) is found primarily in hearts (mainly in cardiomyocytes [CMs]) and β-arrestin-mediated β 1 AR signaling elicits...
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Neurotransmitter Biomarkers
Schizophrenia spectrum disorders (SSD) are characterized as a multidimensional and severe mental illness, involving abnormalities at various levels,...
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A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ
Berberine (BBR) exerts specific therapeutic effects on various diseases such as diabetes, obesity, and other inflammation-associated diseases....
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Calcium Imaging and Amperometric Recording in Cultured Chromaffin Cells and Adrenal Slices from Normotensive, Wistar Kyoto Rats and Spontaneously Hypertensive Rats
The spontaneously hypertensive rat (SHR) is a model widely used to investigate the causal mechanisms of essential hypertension. The enhanced...
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Review Article on Molecular Mechanism of Regulation of Hypertension by Macro-elements (Na, K, Ca and Mg), Micro-elements/Trace Metals (Zn and Cu) and Toxic Elements (Pb and As)
Hypertension (HT) is a medical condition arising due to increase in blood pressure (BP) prevalent worldwide. The balanced dietary intakes of...
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SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy
Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 ( SMN1 ) gene cause multiorgan and metabolic defects in patients...
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Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice
Sympathetic neurons activate thermogenic adipocytes through release of catecholamine; however, the regulation of sympathetic innervation by...
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Regulatory gene network for coffee-like color morph of TYRP1 mutant of oujiang color common carp
BackgroundNeither a TYRP1-mediated highly conserved genetic network underlying skin color towards optimum defense nor the pathological tendency of...
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Cognitive science theory-driven pharmacology elucidates the neurobiological basis of perception-motor integration
An efficient integration of sensory and motor processes is crucial to goal-directed behavior. Despite this high relevance, and although cognitive...
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Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress
BackgroundDuring myocardial damage, the sex hormone estrogen and CD73, the main enzyme that converts AMP into adenosine, are cardioprotective...
