Search
Search Results
-
Synthesis of Some Benzimidazole-Thiophene Hybrids as Potential Urease and Lipase Inhibitors
AbstractIn this study, some benzimidazole-thiophene hybrid compounds containing isatin and salicyl moieties were synthesized and investigated for...
-
Synthesis, antimicrobial activity and molecular docking study of benzyl functionalized benzimidazole silver(I) complexes
In this study, a series of N- functionalized benzimidazole silver(I) complexes were prepared and characterized by FT-IR, 1 H, 13 C{ 1 H} NMR spectroscopy,...
-
Design and synthesis of benzimidazole derivatives as apoptosis-inducing agents by targeting Bcl-2 protein
Bcl-2, an anti-apoptotic protein, is a well-known and appealing cancer therapy target. Novel series of benzimidazole derivatives were synthesized and...
-
Novel Urea Substituted Benzimidazole Derivatives as Anthelmintics: In Silico and In Vitro Approaches
AbstractObjective: Different 5-substituted benzimidazole-2-yl urea derivatives were designed and synthesized to evaluate their anthelmintic...
-
Design, synthesis, molecular docking, and dynamic studies of novel thiazole derivatives incorporating benzimidazole moiety and assessment as antibacterial agents
A general and sustainable approach for the synthesis of benzimidazole-thiazole compounds via an efficient, one-pot, domino, pseudo-four-component...
-
Acetylcholine Inhibitory Study of Novel Thio Linked Coumarin-Benzimidazole Derivatives: Design, Synthesis, Computational, and In Silico Molecular Docking Studies
AbstractObjective: This article focused on the synthesis and characterization of heterocyclic compounds containing two heteroatoms, as well as...
-
Benzimidazole-linked pyrazolo[1,5-a]pyrimidine conjugates: synthesis and detail evaluation as potential anticancer agents
AbstractA library of benzimidazole briged pyrazolo[1,5- a ]pyrimidine ( 6a-q ) was designed, synthesized and subjected for evaluation for cytotoxic...
-
Benzimidazole Derivative NS1619 Inhibits Functioning of Mitochondria Isolated from Mouse Skeletal Muscle
Abstract—The activator of the large-conductance Ca 2+ -activated K + channel (BK Ca ) NS1619 is known to have a pleiotropic action and is able to affect...
-
In silico investigation of falcipain-2 inhibition by hybrid benzimidazole-thiosemicarbazone antiplasmodial agents: A molecular docking, molecular dynamics simulation, and kinetics study
The emergence of artemisinin-resistant variants of Plasmodium falciparum necessitates the urgent search for novel antimalarial drugs. In this regard,...
-
Microbial degradation of the benzimidazole fungicide carbendazim by Bacillus velezensis HY-3479
Carbendazim (methyl benzimidazol-2-ylcarbamate: MBC) is a fungicide of the benzimidazole group that is widely used in the cultivation of pepper,...
-
Occurrence of Cercospora beticola Sacc populations resistant to benzimidazole, demethylation-inhibiting, and quinone outside inhibitors fungicides in Morocco
The sugar beet crop is essential for the production of refined sugar in Morocco. It is cultivated in four large areas (Gharb, Tadla, Doukalla, and...
-
Synthesis and Docking Studies of Novel Benzimidazole Derivatives Containing Thiophene and Triazole Rings as Potential Urease Inhibitors
AbstractA new series of 5,6-dichloro-benzimidazoles containing thiophene ring derivatives of thiosemicarbazides and triazoles were designed,...
-
Synthesis, characterization, photophysical, lipophilicity, and in vitro fluorescence studies of mono-, di-, and trinuclear Ru(II) polypyridyl complexes of pyridinyl benzimidazole derivatives
The synthesis, characterization, and photophysical properties of mononuclear ruthenium(II) complexes [Ru(bpy) 2 (py-BIm-Bz)](ClO 4 ) 2 ( 1 ) and [Ru(phen) 2 (py-BIm-Bz)](ClO...
-
Cu(I)-Promoted Regioselective Synthesis of Some New Benzimidazole-1,2,3-Triazole Frameworks as In Vitro Anticancer Agents
AbstractThe regioselective synthesis of twelve new benzimidazole-1,2,3-triazole hybrids through the Cu(I)-catalyzed 1,3-dipolar cycloaddition...
-
Synthesis of fish scale derived hydroxyapatite silica propyl bis aminoethoxy ethane cuprous complex (HASPBAEECC) as a novel hybrid nano-catalyst for highly efficient synthesis of new benzimidazole-1,2,3-triazole hybrid analogues as antifungal agents
AbstractThe preparation, characterization and application of hydroxyapatite silica propyl bis aminoethoxy ethane cuprous complex (HASPBAEECC) as a...
-
Phototoxicity of cyclometallated Ir(III) complexes bearing a thio-bis-benzimidazole ligand, and its monodentate analogue, as potential PDT photosensitisers in cancer cell killing
AbstractTwo novel cyclometallated iridium(III) complexes have been prepared with one bidentate or two monodentate imidazole-based ligands, 1 and 2 ,...
-
Design, synthesis of benzimidazole tethered 3,4-dihydro-2H-benzo[e] [1, 3] oxazines as anticancer agents
A series of novel 3-(1H-benzo[d]imidazol-2-yl)-3,4-dihydro-2H-benzo[e][1,3] oxazine analogues synthesized through a two-step synthetic protocol. The...
-
Pharmacological Properties of 2-Aminobenzimidazole Halides and Imidazo[1,2-a]Benzimidazole Derivatives
AbstractHalides of 2-aminobenzimidazolium and derivatives of 9-substituted 2-(4-fluorophenyl)imidazo[1,2- a ]benzimidazoles have been studied for ten...
-
Distribution of benzimidazole-resistant strains of the onion gray-mold neck rot pathogens, Botrytis aclada and Botrytis allii, in Hokkaido, Japan
Botrytis aclada and Botrytis allii , associated with onion gray-mold neck rot and isolated in Hokkaido, were tested for sensitivity to benzimidazole....
-
Characterization and sensitivity of Botrytis cinerea to benzimidazole and succinate dehydrogenase inhibitors fungicides, and illustration of the resistance profile
Botrytis cinerea is one of the most destructive ascomycete pathogens affecting crops worldwide and causing severe yield losses. Broad-spectrum...
