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Fighting pathogenic yeasts with plant defensins and anti-fungal proteins from fungi
AbstractFungal infections represent a significant health risk worldwide. Opportunistic infections caused by yeasts, particularly by Candida spp. and...
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Subterranean termites raise the alarm when their anti-fungal weapon falters
Termicin is an anti-fungal defensin that is disseminated from termite salivary glands. The peptide appears to be critical for the elimination with...
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Boxwood phyllosphere fungal and bacterial communities and their differential responses to film-forming anti-desiccants
BackgroundAnti-desiccant is a class of agrochemicals widely used to protect plants from water stresses, rapid temperature variations, heat and...
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Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity
Fungal polysaccharides can exert immunomodulating activity by triggering pattern recognition receptors (PRRs) on innate immune cells such as...
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Mycotoxin levels and characterization of natural anti-fungal phytochemicals in pearl millet (Pennisetum glaucum) from Nigeria’s six agroecological zones
This study reports levels of multiple mycotoxins across Nigeria’s six agro-ecological zones and corresponding levels of natural anti-fungal...
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Advances in anti-fungal therapies
Anti-fungal therapies remain sub-optimal, and resistant pathogens are increasing. New therapies are desperately needed, especially options that are...
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Anti-fungal Effects and Mechanisms of Action of Wasp Venom-Derived Peptide Mastoparan-VT1 Against Candida albicans
Candida albicans , an opportunistic yeast pathogen, is equipped with a plethora of virulence attributes such as yeast-to-hyphae transition, secreted...
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A 5′ tRNA-Ala-derived small RNA regulates anti-fungal defense in plants
Apart from their primordial role in protein synthesis, tRNAs can be cleaved to produce tRNA-derived small RNAs (tsRNAs). The biological functions of...
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Phytochemical analysis and anti-infective potential of fungal endophytes isolated from Nigella sativa seeds
Endophytic fungi, particularly from higher plants have proven to be a rich source of antimicrobial secondary metabolites. The purpose of this study...
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Anti-fungal bioactive terpenoids in the bioenergy crop switchgrass (Panicum virgatum) may contribute to ecotype-specific microbiome composition
Plant derived bioactive small molecules have attracted attention of scientists across fundamental and applied scientific disciplines. We seek to...
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Twenty Years in EUCAST Anti-Fungal Susceptibility Testing: Progress & Remaining Challenges
Since its inception in 2002, the EUCAST Antifungal Susceptibility Testing Subcommittee (AFST) has developed and refined susceptibility testing...
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Anti-fungal properties and mechanisms of melittin
AbstractMany fungal diseases remain poorly addressed by public health authorities, despite posing a substantial threat to humans, animals, and...
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Fruitful decade of fungal metabolites as anti-diabetic agents from 2010 to 2019: emphasis on α-glucosidase inhibitors
In recent years the prevalence of diabetes has increased globally and by 2040 the number of diabetic people has been estimated to increase to 642...
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Anti-fungal effects of novel N-(tert-butyl)-2-(pyridin-2-yl)imidazo[1,2-a]pyridin-3-amine derivative and it’s in-vitro, in-silico, and mode of action against Candida spp.
Imidazoles are a category of azole antifungals that encompass compounds such as ketoconazole, miconazole, esomeprazole, and clotrimazole. In...
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Bacillus subtilis biofilm matrix components target seed oil bodies to promote growth and anti-fungal resistance in melon
Beneficial microorganisms are used to stimulate the germination of seeds; however, their growth-promoting mechanisms remain largely unexplored. Bacillu...
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Anti-fungal, anti-oxidant and phytochemical analysis of Plumbago zeylanica L.
Free radicals play a major role in development of many human diseases like cancer etc. In the present investigation Plumbago zeylanica (Pz) was used...
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Fungal metabolites as anti-diabetic agents: emphasis on PTP1B inhibitors
In the last decade the prevalence of diabetes has escalated globally and it is estimated that the number of diabetic people will increase to 642...
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Evaluation of the Anti-biofilm Efficacy of Kyotorphin Derivatives and Biosafety Assessment: In Vitro and In Vivo Investigations Targeting Bacterial and Fungal Pathogens
Kyotorphin (KTP) dipeptide ( l -Tyrosine- l -Arginine) and their derivatives possess a multitude of functions, qualifying them as "multifunctional...
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Streptomyces griseus Versus Trichoderma viride Chitinase as an Anti-inflammatory and Antifungal Agent Against Human Pathogenic Fungi
Fungal pathogens cause over a billion human infections annually, leading to more than 1.6 million deaths each year. The scarcity of available...
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Selection of green carrier solvent for the effective creation of bio-inspired liquid formulation and anti-fungal potency evaluation
Existing pesticide formulation solvents generate volatile organic compounds (VOCs), are combustible, and are classed as hazardous air pollutants...