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Unique alcohol dehydrogenases involved in algal sugar utilization by marine bacteria
AbstractMarine algae produce complex polysaccharides, which can be degraded by marine heterotrophic bacteria utilizing carbohydrate-active enzymes....
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Flavin-Dependent Dehydrogenases and Oxidases: Comparison of Structural Functional Properties (A Review)
AbstractFlavin-dependent dehydrogenases and oxidases are enzymes that play an important role in living organisms and are widely used in practice....
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Bioinorganic insights of the PQQ-dependent alcohol dehydrogenases
AbstractAmong the several alcohol dehydrogenases, PQQ-dependent enzymes are mainly found in the α , β , and γ -proteobacteria. These proteins are...
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Genome-wide identification and functional characterization of borneol dehydrogenases in Wurfbainia villosa
Main conclusionGenome-wide screening of short-chain dehydrogenases/reductases (SDR) family reveals functional diversification of borneol...
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Phylogenetic and functional diversity of aldehyde-alcohol dehydrogenases in microalgae
Key messageThe study shows the biochemical and enzymatic divergence between the two aldehyde-alcohol dehydrogenases of the alga Polytomella sp.,...
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Regulation of the Activity of Decarboxylating Malate Dehydrogenases in Corn Leaves during an Adaptive Response to Salt Stress
AbstractThe effect of salt stress on the activity of decarboxylating malate dehydrogenases in maize leaves during the adaptive response of cellular...
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A pH-dependent shift of redox cofactor specificity in a benzyl alcohol dehydrogenase of aromatoleum aromaticum EbN1
AbstractWe characterise a reversible bacterial zinc-containing benzyl alcohol dehydrogenase (BaDH) accepting either NAD + or NADP + as a redox...
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Alcohol dehydrogenase system acts as the sole pathway for methanol oxidation in Desulfofundulus kuznetsovii strain TPOSR
Desulfofundulus kuznetsovii is a thermophilic, spore-forming sulphate-reducing bacterium in the family Peptococcaceae . In this study, we describe a...
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Functional analysis of acyl-CoA dehydrogenases and their application to C22 steroid production
AbstractAcyl-CoA dehydrogenase (ChsE) is involved in the steroid side-chain degradation process. However, their function in vivo remains unclear. In...
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Evaluation of the Efficiency of Functional Reversal of Fatty Acid Β-Oxidation in Escherichia coli upon the Action of Various Native Acyl-CoA Dehydrogenases
AbstractUsing Escherichia coli strain MG1655 lacI Q , ∆ ackA-pta , ∆ poxB , ∆ ldhA , ∆ adhE , ∆ fadE , P L ‑SD φ10 - atoB , P trc- ideal-4 -SD φ10 - fadB , P L -SD φ10 - tesB , ∆ yciA...
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Progress of 3-ketosteroid Δ1-dehydrogenases for steroid production
3-ketosteroid Δ 1 -dehydrogenases (Δ 1 -KstDs) are FAD-dependent and substrate-inducing enzymes, which catalyze the introduction of double bonds between...
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Coculture engineering for efficient production of vanillyl alcohol in Escherichia coli
Vanillyl alcohol is a precursor of vanillin, which is one of the most widely used flavor compounds. Currently, vanillyl alcohol biosynthesis still...
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The application of bacteria-derived dehydrogenases and oxidases in the synthesis of gold nanoparticles
AbstractIn this work the green synthesis of gold nanoparticles (Au-NPs) using the oxidoreductive enzymes Myriococcum thermophilum cellobiose...
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Computational identification of potential bioactive compounds from Triphala against alcoholic liver injury by targeting alcohol dehydrogenase
Alcoholic liver injury resulting from excessive alcohol consumption is a significant social concern. Alcohol dehydrogenase (ADH) plays a critical...
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Effects of multi-species probiotic supplementation on alcohol metabolism in rats
Probiotics are known to protect against liver damage induced by the alcohol and acetaldehyde accumulation associated with alcohol intake. However,...
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Efficient synthesis of bepotastine and cloperastine intermediates using engineered alcohol dehydrogenase with a hydrophobic pocket
( S )-4-Chlorophenylpyridylmethanol and ( R )-4-chlorobenzhydrol are key pharmaceutical intermediates for the synthesis of bepotastine and cloperastine,...
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Pecularities and applications of aryl-alcohol oxidases from fungi
AbstractAryl-alcohol oxidases (AAOs) are FAD-containing enzymes that oxidize a broad range of aromatic as well as aliphatic allylic alcohols to...
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Ethylene glycol metabolism in the poly(ethylene terephthalate)-degrading bacterium Ideonella sakaiensis
AbstractPoly(ethylene terephthalate) (PET)-degrading bacterium Ideonella sakaiensis produces hydrolytic enzymes that convert PET, via...
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Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes
We describe a system that allows for biocatalyzed in vivo synthesis of α-hydroxy ketones from racemic epoxide starting material by in vivo...
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Association between alcohol consumption and oesophageal microbiota in oesophageal squamous cell carcinoma
BackgroundMicrobiota has been reported to play a role in cancer patients. Nevertheless, little is known about the association between alcohol...