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Age-dependent sex differences in cardiometabolic risk factors
Cardiometabolic diseases (CMDs) are a major cause of mortality worldwide, yet men and women present remarkable differences in disease prognosis,...
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Iodine Status and Its Influencing Factors in Hospitalized and Healthy Preschool-Age Children
Iodine is a trace element necessary for synthesizing thyroid hormones. It is especially crucial for the neurodevelopment and intellectual development...
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In vivo cyclic overexpression of Yamanaka factors restricted to neurons reverses age-associated phenotypes and enhances memory performance
In recent years, there has been success in partially reprogramming peripheral organ cells using cyclic Yamanaka transcription factor (YF) expression,...
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Key factors to establish the ovalbumin-induced atopic dermatitis minipig model: age and body weight
BackgroundGiven its similar structure and immune response to the human skin, porcine is a good model for dermal studies. Here, we sensitized...
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Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors
The relevance of the human oral microbiome to our understanding of human health has grown in recent years as microbiome studies continue to develop....
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Components of Brown Trout Age-Class Density Dynamics
Brown trout population dynamics are driven by endogenous and exogenous factors acting together or interacting. Endogenous mechanisms include...
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The AP2 transcription factors TOE1/TOE2 convey Arabidopsis age information to ethylene signaling in plant de novo root regeneration
Main conclusionWe reveal that transcription factors TOE1 and TOE2 directly inhibit the transcription of EIN3.
AbstractEthylene triggers leaf...
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Biological maturity and relative age effects in German age-group swimming
Relative age effects (RAE) refer to a skewed distribution with an overrepresentation of athletes born close to the selection date. The prevalence of...
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Factors Affecting Fish Migration
Multiple environmental and endogenous elements work together to cause fish migrations. Abiotic and biotic environmental conditions, such as seasonal...
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Factors Affecting the Composition of the Human Microbiome
The microbiome has recently been considered an important component of the host, and its crucial role in maintaining host health is being unveiled. It...
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Associations of plasma proteomics and age-related outcomes with brain age in a diverse cohort
Machine learning models are increasingly being used to estimate “brain age” from neuroimaging data. The gap between chronological age and the...
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Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases
Aging happens to all of us as we live. Thanks to the improved living standard and discovery of life-saving medicines, our life expectancy has...
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Soil-Forming Factors
The expression of a soil results from five factors operating collectively: climate, organisms, relief, parent material, and time. The factors...
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Age-Area Relationships in American Marsupials: A Macroevolutionary Approach
The range size of a species changes through its persistence and this change may assume complex ways. Understanding such range dynamics may shed light...
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Genetic parameter changes and age−age correlations in Pinus koraiensis growth over 40-year progeny testing
BackgroundEarly selection in tree breeding could be achieved by addressing the longevity of tree improvement activities. Genetic parameter changes...
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A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age
An increase in systemic inflammation (inflammaging) is one of the hallmarks of aging. Epigenetic (DNA methylation) clocks can quantify the degree of...
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Serum MicroRNAs Profiling in Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a progressive, degenerative disease of the retina which ultimately results in the irreversible loss of...
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Age-related effects on a hierarchical structure of canine cognition
The current study investigates whether there are statistically independent age-related influences on the canine cognitive structure and how...
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The genetic architecture of biological age in nine human organ systems
Investigating the genetic underpinnings of human aging is essential for unraveling the etiology of and develo** actionable therapies for chronic...
